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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Trimium Transcaps 15s is used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD). It relaxes the airway muscles and widen the airways. Thus, makes breathing easier for asthma and COPD patients. It may cause side effects such as fungal infection in the mouth, vomiting, nausea, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, Musculoskeletal (bone, muscle, or joint) pain, increased heart rate, and trembling.
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Manufacturer/Marketer

Lupin Ltd

Consume Type

INHALATION

Return Policy

Not Returnable

Expires on or after

Jan-27

About Trimium Transcaps 15s

Trimium Transcaps 15s belongs to the class 'respiratory stimulants', which are primarily used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Trimium Transcaps 15s is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

Your doctor will recommend how often you take Trimium Transcaps 15s based on your medical condition. Some people may experience side effects like a fungal infection in the mouth, vomiting, nausea, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, Musculoskeletal (bone, muscle, or joint) pain, increased heart rate, and trembling. Most of these side effects of Trimium Transcaps 15s do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, stop the medicine and consult your doctor.

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Trimium Transcaps 15s, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Trimium Transcaps 15s. Trimium Transcaps 15s is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Trimium Transcaps 15s as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, tuberculosis inform your doctor before taking Trimium Transcaps 15s. Trimium Transcaps 15s should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.

Uses of Trimium Transcaps 15s

Treatment of Asthma and Chronic obstructive pulmonary disease (COPD).

Medicinal Benefits

Trimium Transcaps 15s is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

Directions for Use

Inhaler/Transhaler: Shake the inhaler well and check the label for directions before using. While you breathe the medication from the mouth, press down the inhaler once to release the medicine and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as advised by your doctor. Rinse your mouth with water and spit it out after using.Rotacaps/Transcaps: It is a capsule with powdered medication which is placed in rotahaler/transhaler, a plastic inhalation device that releases the medication when you breathe. It is for inhalation only. Do not swallow the capsule. The capsule should be placed at the base of the rotahaler/transhaler, and completely twist the mouthpiece until you hear a click sound. Then, breathe in through the mouthpiece deeply and hold your breath for 10 seconds. Remove the device and breathe out normally.Respules/Transpules: Respule/Transpule is a small plastic container that contains a solution. Twist off the top of the respule/transpule and squeeze the solution into the nebuliser. This solution is made into a fine mist to breathe in. Inhale the medicine through the nebuliser's mouthpiece.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trimium Transcaps 15s

  • Fungal infection in the mouth
  • Vomiting
  • Nausea
  • Headache
  • Sore throat, hoarse voice
  • Upper respiratory tract infection
  • Flu, cough
  • Musculoskeletal pain (bone, muscle or joint)
  • Increased heart rate
  • Increased intraocular pressure (pressure inside the eye is higher than normal)
  • Shaking or trembling

Drug Warnings

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Trimium Transcaps 15s, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Trimium Transcaps 15s. Trimium Transcaps 15s is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Trimium Transcaps 15s as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), epilepsy, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, tuberculosis inform your doctor before taking Trimium Transcaps 15s. Trimium Transcaps 15s should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.

Drug Interactions

Drug-Drug Interaction: Trimium Transcaps 15s may interact with bronchodilators (albuterol), steroids (prednisone), diuretics (furosemide, amiloride), pain killers (aspirin), antibiotics (azithromycin), antidepressants (duloxetine), heart-related medicines (metoprolol), antifungals (itraconazole, voriconazole, posaconazole, ketoconazole), HIV/AIDS drugs (ritonavir), mono-amino oxidase inhibitors (phenelzine),

Drug-Food Interaction: Trimium Transcaps 15s may interact with grapefruit and grapefruit juice. Therefore, avoid grapefruit or its juice with Trimium Transcaps 15s as it may lead to severe adverse effects.

Drug-Disease Interaction: If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), epilepsy, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, prostatic hyperplasia or bladder neck obstruction, tuberculosis, inform your doctor before taking Trimium Transcaps 15s.

Drug-Drug Interactions Checker List

  • ALBUTEROL
  • PREDNISONE
  • FUROSEMIDE
  • AMILORIDE
  • ASPIRIN
  • AZITHROMYCIN
  • DULOXETINE
  • METOPROLOL
  • KETOCONAZOLE
  • RITONAVIR
  • PHENELZINE
  • POSACONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon, and lime juice as it may worsen asthma symptoms.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
  • Quit smoking as it may reduce the effectiveness of the Trimium Transcaps 15s and irritate the lungs worsening breathing problems.
  • Learning breathing exercises will help you move more air in and out of your lungs.
  • Limit alcohol intake.

Special Advise

  • You are advised to rinse your mouth with water after each dose of Trimium Transcaps 15s because it not only removes the taste of medicine inhaled but also helps to avoid fungal infections (oral thrush) in the mouth and throat. After rinsing your mouth thoroughly, you may drink water, milk, or any liquids.
  • Your doctor may advise regular monitoring of potassium, as the use of Trimium Transcaps 15s may affect the body's potassium levels.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises, and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).

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Alcohol

Caution

The interaction of Trimium Transcaps 15s with alcohol is unknown. Please consult a doctor before consuming alcohol with Trimium Transcaps 15s.

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Pregnancy

Caution

The safety of Trimium Transcaps 15s in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Trimium Transcaps 15s is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Trimium Transcaps 15s usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Trimium Transcaps 15s with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Trimium Transcaps 15s in patients with Kidney problems, please consult your doctor.

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Children

Caution

Safe for children below 12 years(Content)Trimium Transcaps 15s is not recommended for children below 6 years as the safety and effectiveness were not established. However, please consult a doctor before giving Trimium Transcaps 15s to children.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - TRI1299

Author Details

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FAQs

Trimium Transcaps 15s is used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD).
Yes, Trimium Transcaps 15s may cause fungal infection in the mouth (oral thrush) is a common side effect. It is not necessary for everyone taking Trimium Transcaps 15s to experience this side effect. However, to avoid such side effects, brush your teeth or rinse your mouth with water after using Trimium Transcaps 15s every time.
You are not recommended to stop taking Trimium Transcaps 15s without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Trimium Transcaps 15s for as long as your doctor has prescribed it.
People with heart problems (including high blood pressure, chest pain, fast heartbeat, fits (seizures), thyroid problems, diabetes, immune system problem, weak bones or osteoporosis, eye problems (glaucoma, cataracts), and liver problems should consult a doctor before using Trimium Transcaps 15s.
Yes, Trimium Transcaps 15s causes dry mouth/ dry throat as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake, and sugarless candy may help to relieve dry mouth/dry throat.
Trimium Transcaps 15s should be used with caution in osteoporosis (low bone density resulting in weak and brittle bones) patients as it may worsen the condition. Therefore, inform your doctor if you have osteoporosis before taking Trimium Transcaps 15s so that the dose may be adjusted or an alternate medicine may be prescribed.

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