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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Tresiba 100U/ml Flextouch 3 ml is used for the treatment of type 1 and type 2 diabetes mellitus in both children (above 1 year of age) and adults. It contain Insulin degludec, which is a fast-acting insulin that works rapidly to normalize blood sugar levels by helping the sugar move from the blood into other tissues of the body. It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver. It may cause common side effects such as hypokalaemia (low potassium), hypoglycemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin) which may occur at the injection site.
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Manufacturer/Marketer

Novo Nordisk India Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Tresiba 100U/ml Flextouch 3 ml

Tresiba 100U/ml Flextouch 3 ml belongs to a group of medication called 'anti-diabetic' primarily used for the treatment of type 1 and type 2 diabetes mellitus in both children (above 1 year of age) and adults. Diabetes is a disease where your body does not produce enough insulin to control the level of your blood sugar. Treatment with Tresiba 100U/ml Flextouch 3 ml helps to prevent complications from your diabetes.

Tresiba 100U/ml Flextouch 3 ml contains insulin degludec which is a fast-acting insulin that works rapidly to normalize blood sugar levels by helping the sugar move from the blood into other tissues of the body. It typically begins working after 60 minutes and is a long-acting insulin preparation (lasts for more than 24 hours). It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver.

In patients with type 1 diabetes, Tresiba 100U/ml Flextouch 3 ml must be used with another type of insulin (like with short-acting insulin). On the other hand, in patients with type 2 diabetes, Tresiba 100U/ml Flextouch 3 ml can be used with another type of insulin or with oral antidiabetic medicines. The common side effects of Tresiba 100U/ml Flextouch 3 ml are hypokalaemia (low potassium), hypoglycemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin) which may occur at the injection site. Most of these side effects of Tresiba 100U/ml Flextouch 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Tresiba 100U/ml Flextouch 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Tresiba 100U/ml Flextouch 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Tresiba 100U/ml Flextouch 3 ml, you should take a healthy diet, do regular exercise, and maintain weight as advised by your doctor. Tresiba 100U/ml Flextouch 3 ml is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might get lost. Do not store in the freezer of the fridge.

Uses of Tresiba 100U/ml Flextouch 3 ml

Treatment of Type 1 diabetes mellitus, Type 2 diabetes mellitus.

Medicinal Benefits

Tresiba 100U/ml Flextouch 3 ml works by ensuring rapid and consistent sugar control. Tresiba 100U/ml Flextouch 3 ml is a long-acting synthetic form of insulin that helps lower blood sugar levels by replacing the insulin that is produced by the body naturally. This drug also helps in moving sugar from the blood into different parts of the body so that body can effectively use the sugar in producing energy. Prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver. Tresiba 100U/ml Flextouch 3 ml helps in improving the glycaemic control which in turn decreases the risk of progression of complications of diabetes like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer, and others. Besides this, Tresiba 100U/ml Flextouch 3 ml can be safely prescribed to the diabetic mother in the pregnancy as well as lactation stage.

Directions for Use

Tresiba 100U/ml Flextouch 3 ml is for subcutaneous (under the skin) use only. However, in rare cases, it can be given via infusion intravenously under medical supervision. Wash your hands properly and adjust the dose as advised by the doctor. Clean the injection site and inject the dose subcutaneously into the abdomen area. Safely discard the needle. Your doctor will advise you on how long you need to take Tresiba 100U/ml Flextouch 3 ml based on your medical condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tresiba 100U/ml Flextouch 3 ml

  • Hypokalaemia (low potassium)
  • Hypoglycemia (low blood sugar level)
  • Local injection site reactions
  • Lipodystrophy (fat deposition under the skin)
  • Rash
  • Pruritus (itchy skin)

Drug Warnings

Tresiba 100U/ml Flextouch 3 ml is for subcutaneous (under the skin) use only. However, in rare cases, it can be given via infusion intravenously under medical supervision. If you are changing the insulin brand or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first hyperglycemia symptoms (high blood sugar level) may include excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite, and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain, and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may either increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Tresiba 100U/ml Flextouch 3 ml may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma, and even death. Do not take Tresiba 100U/ml Flextouch 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug Interactions

Drug-Drug Interaction: Tresiba 100U/ml Flextouch 3 ml may have an interaction with drugs that may increase the risk of antiarrhythmic (disopyramide), hemorheological agents (pentoxifylline), antidiabetic (pramlintide), bleeding disorder drugs (octreotide), antipsychotic (propoxyphene, phenothiazines), female sex hormones (progestogen, oestrogen), thyroid hormones (levothyroxine), anti-asthmatics (albuterol, epinephrine, terbutaline), an antidepressant (fluoxetine, lithium), lipid-lowering pills (reserpine, niacin, clonidine, fenofibrate, guanethidine), pain killers (aspirin), antibiotics (isoniazid), blood sugar enhancing pills (glucagon), male hormone testosterone analogue (danazol), antibiotic (pentamidine).

Drug-Food Interaction: Tresiba 100U/ml Flextouch 3 ml may interact with an ayurvedic, homoeopathy, Unani, herbal supplements or OTC items. Tell your doctor if you are using these products. Try to avoid alcoholic beverages with Tresiba 100U/ml Flextouch 3 ml as it may increase or decrease your blood sugar level.

Drug-Disease Interaction: Tresiba 100U/ml Flextouch 3 ml should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).

Drug-Drug Interactions Checker List

  • LEVOTHYROXINE SODIUM
  • METOPROLOL
  • FUROSEMIDE
  • ASPIRIN

Habit Forming

No

Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and for some time after the physical activity.

  • Exercise may also speed up the effect of an insulin dose, especially if the exercise involves the area of the injection site (for example, the leg should not be used for injection just prior to running). 

  • Discuss with your doctor how you should adjust your insulin regimen to accommodate exercise. 

  • Avoid eating sugar food and prefer food cooked food low in calories.

  • When traveling across more than 2 time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

Special Advise

  • Your doctor may tell you to have a regular potassium level as prolonged administration causes a life-threatening condition of hypokalemia (low potassium). 
  • Do not mix Tresiba 100U/ml Flextouch 3 ml with other insulin form or dilute it.
  • Store Tresiba 100U/ml Flextouch 3 ml between 2-8 degree celsius temperature only. 

Disease/Condition Glossary

Type 1 diabetes mellitus: In type 1 diabetes mellitus, our body does not make insulin (the hormone which helps to decrease sugar levels in the blood) to control blood sugar levels.

Type 2 diabetes mellitus: In type 2 diabetes mellitus, either the body stops producing enough insulin, or there is resistance to the action of insulin. As a result, insulin is produced in sufficient amounts but is unable to act on the tissues of the organs.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Tresiba 100U/ml Flextouch 3 ml to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

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Pregnancy

Safe if prescribed

Tresiba 100U/ml Flextouch 3 ml can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery.

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Breast Feeding

Safe if prescribed

Tresiba 100U/ml Flextouch 3 ml can be given safely to nursing mothers but only under the supervision of a physician.

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Driving

Unsafe

Drive with caution, Tresiba 100U/ml Flextouch 3 ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

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Liver

Caution

Tresiba 100U/ml Flextouch 3 ml to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Tresiba 100U/ml Flextouch 3 ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Tresiba 100U/ml Flextouch 3 ml can be given safely to children more than 1-year-old; dose has to be prescribed by a child specialist.

Country of origin

India

Manufacturer/Marketer address

Plot No.32, 47-50, EPIP Area, Whitefield, Bangalore - 560 066
Other Info - TRE0144

Author Details

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FAQs

Tresiba 100U/ml Flextouch 3 ml is used for the treatment of type 1 and type 2 diabetes mellitus in both children (above 1 year of age) and adults.
Tresiba 100U/ml Flextouch 3 ml is only a part of a complete diabetes control program that includes regular blood sugar testing, diet, exercise, weight control, and special medical care. So follow all the instructions given by the doctor.
It is advised to tell all the medicines that you are using like pioglitazone or rosiglitazone as taking other diabetes medicines may increase the risk of serious heart problems.
Tresiba 100U/ml Flextouch 3 ml typically begins working after 60 minutes and will last for more than 24 hours.
Tresiba 100U/ml Flextouch 3 ml can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Tresiba 100U/ml Flextouch 3 ml can be given to you or not depending on your present condition. Tresiba 100U/ml Flextouch 3 ml should be avoided in patients who are allergic to Tresiba 100U/ml Flextouch 3 ml or other forms of insulin, patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycemia), and low potassium level (hypokalaemia).
Try to avoid intake of alcoholic beverages with Tresiba 100U/ml Flextouch 3 ml as it may increase or decrease your blood sugar level.
Cold sweat; cool pale skin; headache; rapid heartbeat; feeling sick; feeling very hungry; temporary vision changes; drowsiness; unusual tiredness and weakness; nervousness or tremor; feeling anxious; feeling confused; difficulty in concentrating are some of the common signs of the low blood sugar level in an individual.
If you experience low blood sugar, eat glucose tablets, or another high sugar snack (e.g. sweets, biscuits, fruit juice). Measure your blood sugar if possible and rest. Always carry glucose tablets or high sugar snacks with you. You should give a call to any of your family members if you are feeling dizziness or drowsiness.
Local allergic reactions (pain, redness, hives, inflammation, bruising, swelling, and itching) at the injection site may occur. These usually disappear after a few weeks of taking your insulin. If they do not disappear, or if they spread throughout your body, talk to your doctor immediately.
You can inject Tresiba 100U/ml Flextouch 3 ml in your upper arm, thigh, or stomach area. Do not inject Tresiba 100U/ml Flextouch 3 ml into your vein or muscle. Try to change (rotate) the injection site with each dose to avoid skin irritation in the same injection site.
If you have opened the insulin pen once, it must be stored at room temperature (25-degree Celsius) and may be used for up to 56 days after its first use.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
Tresiba 100U/ml Flextouch 3 ml should not be discontinued without a doctor's consultation as stopping Tresiba 100U/ml Flextouch 3 ml may cause severe hypoglycaemia (low blood sugar) and ketoacidosis (buildup of acid in the blood). Consult the doctor if you feel uncomfortable after taking Tresiba 100U/ml Flextouch 3 ml.
The injection site should be changed to prevent skin changes like lumps under the skin. Tresiba 100U/ml Flextouch 3 ml may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Tresiba 100U/ml Flextouch 3 ml is a long-acting human insulin analogue produced by rDNA process in Saccharomyces cerevisiae followed by chemical modification.
No, insulin glargine and Tresiba 100U/ml Flextouch 3 ml are not the same. Tresiba 100U/ml Flextouch 3 ml contains insulin degludec which has a longer half-life compared to insulin glargine. Insulin degludec and insulin glargine provide similar glycemic control, but insulin degludec also lowers the risk of low blood sugar.
Tresiba 100U/ml Flextouch 3 ml contains insulin degludec. Insulin degludec and insulin detemir were found to be equally effective in managing blood sugar levels.
Avoid sharing Tresiba 100U/ml Flextouch 3 ml, insulin syringe or needle with other patients. Do not miss meals and regularly monitor blood sugar levels. Avoid driving or operating machinery until you know how this medicine affects you. Do not consume alcohol or use prescription or over-the-counter medicines that contain alcohol.
Yes, Tresiba 100U/ml Flextouch 3 ml can be used alone to treat diabetes. However, Tresiba 100U/ml Flextouch 3 ml can be used with other diabetic medicines if prescribed by the doctor.
Yes, Tresiba 100U/ml Flextouch 3 ml is a long-acting basal human insulin analogue that is used to improve glycaemic control in patients with diabetes mellitus.
Yes, Tresiba 100U/ml Flextouch 3 ml can cause weight gain due to the anabolic effects of insulin. Eating healthy food and exercising regularly may help manage weight gain.
Tresiba 100U/ml Flextouch 3 ml does not raise blood sugar. However, hyperglycaemia has been reported with repeated insulin injections into areas of localised cutaneous amyloidosis (clumps of abnormal proteins called amyloids build up in the skin). Also, changes in insulin regimen may cause high/low blood sugar levels.
Side effects of Tresiba 100U/ml Flextouch 3 ml include hypoglycaemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itching skin) which may occur at the injection site. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

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