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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 22, 2024 | 7:36 PM IST
Topme-XL 50mg Tablet is used to treat high blood pressure, chest pain, heart attack and irregular heartbeat. It may also be used to treat overactive thyroid and prevent migraine attacks. It contains Metoprolol tartrate which works by relaxing the blood vessels decreasing the workload on the heart. This medicine may sometimes cause side effects such as headache, dizziness, unusual tiredness, nausea, and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Johnlee Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Topme-XL 50mg Tablet

Topme-XL 50mg Tablet belongs to a group of medicines called “Antihypertensive” used alone or together with other drugs to treat high blood pressure (hypertension), symptoms caused by an overactive thyroid gland, heart-related chest pain (angina), heart rhythm disorder (arrhythmia). Besides this, it also helps in relieving symptoms of migraine-related headaches. High blood pressure adds to the workload of the heart and arteries. Hypertension or high blood pressure is a long-term force of the blood against the arteries that may lead to various heart diseases. It can damage the blood vessels (arteries) of the brain, heart, and kidneys if it continues for a long time, resulting in a stroke, heart failure or kidney failure. Lowering blood pressure reduces the risk of stroke, heart attack and heart-related chest pain (angina).

Topme-XL 50mg Tablet plays a vital role in relaxing blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier for pumping more blood around the body. This lowers your blood pressure and reduces the risk of having a stroke, a heart attack, other heart problems or kidney problems in the future. Topme-XL 50mg Tablet needs to be taken regularly to be effective.

You are advised to take this medicine for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects, such as tiredness, dizziness, stomach pain, nightmares, irregular heart rate and skin rash. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. However, you are advised to talk to your doctor if you experience these side effects persistently.

Don't stop taking this medicine without talking to your doctor first. Stopping abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. Topme-XL 50mg Tablet should not be used to avoid heart attacks. You should not use Topme-XL 50mg Tablet if you have heart rhythm problems, diabetes, kidney disease or failure, COPD (Chronic Obstructive Pulmonary Disease). Avoid driving and operating heavy machinery as it may cause dizziness and drowsiness. Orthostatic hypotension (sudden lowering of blood pressure n standing) might occur so patients using Topme-XL 50mg Tablet should get up with caution. Before taking Topme-XL 50mg Tablet, inform your doctor if you are going to have surgery or an anaesthetic.

Uses of Topme-XL 50mg Tablet

Treatment of Hypertension (high blood pressure), Angina (heart-related chest pain), Arrhythmia (heart rhythm disorder), Heart failure, Stroke, Migraine.

Medicinal Benefits

Topme-XL 50mg Tablet contains Metoprolol tartrate that works by blocking beta receptors, namely beta 1 and beta 2. Topme-XL 50mg Tablet blocks beta 1 receptor located in the heart cells that lower heart rate and decreases the heart's blood pumping frequency decreasing raised blood pressure. On the other hand, Topme-XL 50mg Tablet also blocks beta 2 receptors located in the lungs (bronchioles) and blood vessels of skeletal muscle narrowing it. This, in turn, lowers your overall body's blood pressure and helps in reducing the risk of having a stroke, heart problems, or kidney problems in the future. A Topme-XL 50mg Tablet also improves heart-related chest pain (angina) and may increase a person's stamina to exercise with angina. It also blocks the effects of epinephrine, which causes the heart to beat slower. Additionally, Topme-XL 50mg Tablet reduces symptoms of essential tremor (fits), and prevent migraine. Topme-XL 50mg Tablet can reduce symptoms of too much thyroid hormone (thyrotoxicosis) and can be taken together with thyroid-related medicines to treat an overactive thyroid.

Side Effects of Topme-XL 50mg Tablet

  • Tiredness
  • Dizziness
  • Headache
  • Stomach pain
  • Anxiety
  • Irregular heart rate

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Topme-XL 50mg Tablet if you are allergic (hypersensitive) to Topme-XL 50mg Tablet or any ingredients present in it. Please consult your doctor before taking Topme-XL 50mg Tablet if you are pregnant or planning to conceive, and breastfeeding. It should not be given to children. Don't stop taking Topme-XL 50mg Tablet without talking to your doctor first. Stopping Topme-XL 50mg Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. Before taking Topme-XL 50mg Tablet, inform your doctor if you have diabetes mellitus, liver cirrhosis, myasthenia gravis, psoriasis, or if you have a slow heart rate or blood vessel disorder. Do not take Topme-XL 50mg Tablet with medicines like monoamine oxidase inhibitors (MAOIs) for depression, other blood pressure-lowering medicines such as nifedipine, verapamil, diltiazem disopyramide or quinidine (to treat irregular heartbeat). Inform your doctor about all your current ongoing medications before taking Topme-XL 50mg Tablet. Do not consume alcohol while on this medication.

Therapeutic Class

ANTI- HYPERTENSIVES

Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.

  • Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

What if I have taken an overdose of Topme-XL 50mg Tablet

Take Topme-XL 50mg Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include bradycardia (slow heart rate), hypotension (low blood pressure), bronchospasm (tightening of airway muscles), and cardiac failure. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Unsafe

Drinking alcohol may increase tiredness, lower blood pressure causing dizziness or drowsiness. So avoid its intake with Topme-XL 50mg Tablet.

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Pregnancy

Caution

Topme-XL 50mg Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Topme-XL 50mg Tablet is not recommended if you are breast-feeding women unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Unsafe

You may experience dizziness, tiredness, or blurred vision while taking Topme-XL 50mg Tablet. So, it is not recommended to drive, use machinery, or perform other tasks.

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Liver

Caution

Topme-XL 50mg Tablet is not recommended in patients with liver disease or failure. Your doctor may prescribe Topme-XL 50mg Tablet depending on your condition.

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Kidney

Caution

Topme-XL 50mg Tablet is not recommended in patients with kidney disease or failure. Your doctor may prescribe Topme-XL 50mg Tablet depending on your condition.

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Children

Unsafe

The safety and efficacy of Topme-XL 50mg Tablet in children have not been established.

Country of origin

India
Other Info - TO50154

Author Details

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FAQs

Topme-XL 50mg Tablet is used to treat High blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction)
Topme-XL 50mg Tablet contains 'metoprolol tartrate ' that reduces blood pressure by allowing the blood to flow more smoothly. It belongs to a class of medications known as beta-blockers. It works by inhibiting the action of natural chemicals such as epinephrine in the body. This effect helps to reduce the blood pressure, heart rate and strain on the heart.
Use of Topme-XL 50mg Tablet in diabetes may mask tachycardia (fast heart rate) occurring with low blood sugar level, but other symptoms like dizziness and sweating may not be significantly affected. So, if you are diabetic patients always consult a doctor before taking Topme-XL 50mg Tablet.
Your doctor may probably tell you to stop taking Topme-XL 50mg Tablet as it lowers blood pressure (hypotension) when combined with a certain general anaesthetic before surgery. So, please inform your doctor before surgery if you are taking Topme-XL 50mg Tablet.
It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up at any time. If you have any discomfort, please consult your doctor immediately.
Topme-XL 50mg Tablet may increase your blood potassium level. So potassium-rich diet and supplements should be avoided while taking Topme-XL 50mg Tablet to avoid any unpleasant side effects. Talk to your doctor for more information regarding this.
Metoprolol tartrate and metoprolol succinate are both similar in effectiveness for treating high blood pressure and chronic chest pain. However, metoprolol tartrate may be more effective as a treatment for acute heart attacks while metoprolol succinate may be more effective as a treatment for chronic heart failure.
The side effects of Topme-XL 50mg Tablet include stomach pain, dizziness, tiredness, anxiety, headache or irregular heartbeat. If these side effects persist or worsen, please consult your doctor.
Yes, Topme-XL 50mg Tablet is a selective beta-blocker, that acts on the heart muscles.
No, Topme-XL 50mg Tablet is not a blood thinner. Topme-XL 50mg Tablet relaxes the blood vessels, and slows down the heart rate. Thereby, it reduces the workload on the heart and makes it easier to pump blood effectively.
The time taken by Topme-XL 50mg Tablet to start working varies from person to person. Usually, it starts working within 15 minutes. However, it may take up to 2 hours to start working in some people. The maximum or full effect is usually achieved within 1 week as it starts acting slowly. In case you do not feel any difference while taking Topme-XL 50mg Tablet, do not worry. It exerts its beneficial effects when taken for a long time.
Topme-XL 50mg Tablet is generally safe if used as prescribed by the doctor. If this medication is stopped suddenly, it may cause harmful effects such as sudden increase in the heart rate and affect its activity, which can be dangerous for heart failure patients and in some cases even result in a heart attack. Therefore, take Topme-XL 50mg Tablet for the prescribed duration and do not stop taking suddenly.
Topme-XL 50mg Tablet belongs to the class of medicines called beta-blockers. Though their effect on sleep differs from person to person, it has been found that these medications are known to change the sleep pattern and disturb sleep in some patients. On the other hand, it has also been observed to promote better sleep in patients with increased anxiety and heart rate by calming down the nerves and heart. If you have any sleep disturbances, please consult your doctor.
No, you are recommended to avoid alcohol consumption after taking Topme-XL 50mg Tablet as alcohol might increase the blood pressure-lowering effect of Topme-XL 50mg Tablet and might cause increased dizziness.

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