Topisal-3% Lotion is a combination of two medicines that are primarily used to treat eczema and psoriasis. Eczema is a condition in which skin patches become inflamed, itchy, cracked, and rough. Some types of eczema can also lead to blisters (a small bubble on the skin that is filled with serum and is caused by friction, burning, or other damage). Psoriasis is a skin disorder in which skin cells multiply up to 10 times faster than normal which leads to the build-up of skin into bumpy (uneven) red patches covered with white scales. These can grow anywhere, but most commonly they appear on the scalp, elbows, knees and lower back.

Topisal-3% Lotion comprises clobetasol and salicylic acid. Clobetasol is a steroid that works by blocking the production of certain chemical messengers (prostaglandins) that are responsible for making the skin red, swollen, and itchy. Salicylic Acid is a keratolytic medicine (that softens, separates, and causes desquamation (peeling) of the cornified epithelium or horny layer of skin) which breaks down the clumps of keratin, removes dead skin cells, and helps in softening of the skin. It also helps in the absorption of Clobetasol into the skin.

Topisal-3% Lotion should be used in the dose and duration as advised by the doctor. It is advised to check the label for directions before use. It is for external use only. Make sure to wash your hands before and after using this medicine. Topisal-3% Lotion is generally safe to use. Some may experience side effects such as peeling of the skin, thinning of the skin, burning, itching, irritation, and redness at the application site. Please consult your doctor if you experience a worsening of any side effect.

Do not stop using Topisal-3% Lotion without consulting your doctor. Please inform your doctor if you are pregnant or are suffering from any other disease. Topisal-3% Lotion is safe to use in breastfeeding mothers. Inform your doctor if you are allergic to Topisal-3% Lotion.

When you take Topisal-3% Lotion, it works by blocking the production of certain chemical messengers (prostaglandins) that are responsible for making the skin red, swollen, and itchy. It softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin and breaks down the clumps of keratin, removes dead skin cells and helps in the softening of the skin.

• Peeling of the skin
• Thinning of the skin
• Burning, itching, irritation, and redness at the application site

Topisal-3% Lotion should be used with caution for a long time as long-term usage can pose the risk of adrenal gland problems. It is advised to discontinue this medicine if you experience symptoms like blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness.

Drug-Drug Interaction: Topisal-3% Lotion is shown to interact with various drugs. Some of them include HIV medicines such as ritonavir), medicines used to treat fungal infections such as itraconazole, medicines used for heart attacks such as aspirin, a medicine used for allergy, antidepressant such as Cymbalta. These drugs may affect the working of Topisal-3% Lotion and may alter its efficacy.

Drug-Food Interaction: If you are taking any homoeopathic, ayurvedic, Unani or any OTC items let your doctor know about this. These medicines may interact with Topisal-3% Lotion and affect its working.

Drug-Disease Interaction: Diseases that may have interactions with Topisal-3% Lotion include diabetes, diaper rash, infections and ocular toxicities.

• RITONAVIR
• ITRACONAZOLE
• ASPIRIN
• CYMBALTA

• Use mild soap while taking baths and prefer warm baths.
• Avoid harsh products on your skin.
• Do not scratch or pick your skin to avoid getting the affected area infected.
• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

Topisal-3% Lotion is not advised to use with other topical corticosteroid-containing medicines, such as betamethasone, hydrocortisone, or triamcinolone as it may lead to unpleasant side effects. It is not advised to use cosmetic products in the affected area. Inform your doctor if you are taking aspirin.

Eczema: It is a condition in which skin patches become inflamed, itchy, cracked, and rough. Some types of eczema can also lead to blisters (a small bubble on the skin that is filled with serum and is caused by friction, burning, or other damage).

Psoriasis: It is a skin disorder in which skin cells multiply up to 10 times faster than normal which leads to the buildup of skin into bumpy (uneven) red patches covered with white scales. These can grow anywhere, but most commonly they appear on the scalp, elbows, knees, and lower back.