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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Tobamist Respules 5X5 ml is an aminoglycoside antibiotic used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis. It helps by inhibiting the protein synthesis of the bacterial cell and therby helps fight infection in the lungs. Sometimes, you may experience certain common side effects, such as discolouration of the substance you cough up (sputum), worsening of lung function test results, runny or stuffy nose, sneezing, hoarseness,feeling unwell, muscle pain, etc
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Composition

TOBRAMYCIN-300MG

Manufacturer/Marketer

Cipla Ltd

Consume Type

INHALATION

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Tobamist Respules 5X5 ml

Tobamist Respules 5X5 ml belongs to the class of aminoglycoside antibiotics. Tobamist Respules 5X5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older. Pseudomonas aeruginosa is a type of bacteria that can cause lung or chest infections, especially in people who already have a lung disease (cystic fibrosis) or an issue with their immune system.

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights the infection in your lungs by interfering with protein synthesis in Pseudomonas bacterial cell and helps you breathe better.

Use the Tobamist Respules 5X5 ml as prescribed by your doctor. Sometimes, you may experience certain common side effects, such as runny or stuffy nose, sneezing, voice alteration (hoarseness), discolouration of the substance you cough up (sputum), worsening of lung function test results, feeling unwell, muscle pain and voice alteration with sore throat and difficulty swallowing (laryngitis). Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Tobamist Respules 5X5 ml if you are allergic to any of its components or other aminoglycoside antibiotics. Do not use the Tobamist Respules 5X5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobamist Respules 5X5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Tobamist Respules 5X5 ml is not recommended to be used in children under the age of six.

Uses of Tobamist Respules 5X5 ml

Treatment of Chest infections (Pseudomonas aeruginosa infection)

Medicinal Benefits

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

Directions for Use

Check the label for directions before using the Tobamist Respules 5X5 ml. It is for inhalation only. Do not swallow the respules. Use it in the dose and for the duration advised by your doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tobamist Respules 5X5 ml

  • Runny or stuffy nose, sneezing
  • Voice alteration (hoarseness)
  • Discolouration of the substance you cough up (sputum)
  • Worsening of lung function test results
  • Generally feeling unwell
  • Muscle pain
  • Voice alteration with a sore throat
  • Difficulty swallowing (laryngitis)

Drug Warnings

Do not use Tobamist Respules 5X5 ml if you are allergic to any of the components or other aminoglycoside antibiotics (neomycin, paromomycin, kanamycin). Do not use the Tobamist Respules 5X5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobamist Respules 5X5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six. Before taking the Tobamist Respules 5X5 ml, notify your doctor about your medical history and other medications you are now taking to rule out any potential adverse effects or interactions.

Drug Interactions

Drug-Drug interactions: Tobamist Respules 5X5 ml may interact with bronchodilators (e.g. salbutamol), diuretic medications (e.g. furosemide, ethacrynic acid) and medicines that lower pressure in the head (e.g. intravenous mannitol).

Drug-Food interactions: Relevant interactions could not be found/established.

Drug-Disease interactions: Inform your doctor if you have hearing problems, kidney or liver problems, chest tightness, blood in the sputum, dehydration, muscle disorders, poisoning caused by toxins, hypocalcaemia (levels of calcium in your blood are too low), diarrhoea, vomiting, myoneural disease (neuromuscular disorder) and unusual difficulty breathing with wheezing or coughing.

Drug-Drug Interactions Checker List

  • SALBUTAMOL
  • FUROSEMIDE
  • ETHACRYNIC ACID
  • MANNITOL

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Tobamist Respules 5X5 ml to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Tobamist Respules 5X5 ml.
  • Avoid intake of alcoholic beverages with Tobamist Respules 5X5 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Tobamist Respules 5X5 ml in fighting off infections.

Disease/Condition Glossary

Pseudomonas aeruginosa infection: Pseudomonas aeruginosa is a type of bacteria that can cause lung or chest infections, especially in people who already have a lung disease (cystic fibrosis) or an issue with their immune system.

Cystic fibrosis: Cystic fibrosis is a hereditary disease that affects the digestive system and lungs. In this condition, the body produces a thick, sticky fluid that obstructs the pancreas and clogs the lungs.

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Alcohol

Caution

It is unknown if alcohol affects Tobamist Respules 5X5 ml. However, it is advisable to limit or avoid alcohol as a precautionary measure.

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Pregnancy

Caution

Tobamist Respules 5X5 ml may not be recommended to be used in pregnancy. If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on using Tobamist Respules 5X5 ml in breastfeeding/nursing mothers.

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Driving

Safe if prescribed

Tobamist Respules 5X5 ml may not affect your ability to drive, use, or operate machines.

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Liver

Caution

Limited information about the usage of Tobamist Respules 5X5 ml in patients with liver disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Kidney

Caution

Limited information about the usage of Tobamist Respules 5X5 ml in patients with kidney disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Children

Caution

Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - TOB0011

Author Details

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FAQs

Tobamist Respules 5X5 ml belongs to the class of aminoglycoside antibiotics. Tobamist Respules 5X5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older.
Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.
Please do not stop using Tobamist Respules 5X5 ml until the course prescribed by your doctor has been completed. If you stop taking Tobamist Respules 5X5 ml too soon, your symptoms may recur.
Voice alteration (hoarseness) is the most common side effect of Tobamist Respules 5X5 ml. If you experience any major changes, immediately consult your doctor.
Tobamist Respules 5X5 ml is recommended not to use it for more than the prescribed duration. Please reach out to your doctor if your symptoms do not improve or if it becomes worse.
Tobamist Respules 5X5 ml is only used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients.

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