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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:06 PM IST
Tigesine 50mg Injection is used to treat bacterial infections. It contains Tigecycline which works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

TIGECYCLINE-50MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Tigesine 50mg Injection

Tigesine 50mg Injection belongs to the class of 'antibiotics,' primarily used to treat bacterial infections like abdominal infections, community-acquired pneumonia (lung infection), and complicated skin and skin structure infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Tigesine 50mg Injection does not work for viral infections, such as common cold and flu.

Tigesine 50mg Injection contains 'Tigecycline' that belongs to the class of 'glycylcyclines'. It works by preventing the synthesis of bacterial proteins, which are the primary cursors for carrying out bacteria's vital functions. This process further inhibits bacterial growth. 

Tigesine 50mg Injection will be administered by a healthcare professional; do not self-administer it. Your doctor will decide the dose and duration of Tigesine 50mg Injection based on your medical condition. Like all medicines, Tigesine 50mg Injection also causes side effects, although not everybody gets them. Common side effects of Tigesine 50mg Injection include nausea, vomiting, diarrhoea, headache, and abnormal liver function tests. If any of these effects persist or worsen, seek medical advice promptly.

Brief your medical history to the doctor if you are allergic to Tigesine 50mg Injection or any of its components. Let your doctor know if you have any kidney or liver diseases, colitis (inflammation of the inner lining of the colon), and pancreatitis (inflammation of the pancreas). Tigesine 50mg Injection is not recommended during pregnancy due to its harmful effects on the baby. It is advised to consult your doctor if you are breastfeeding before taking Tigesine 50mg Injection. Tigesine 50mg Injection can make you feel dizzy; hence drive or operate machinery only when you are alert. Tigesine 50mg Injection is not recommended in children below eight years of age. 

Uses of Tigesine 50mg Injection

Treatment of Bacterial infections.

Medicinal Benefits

Tigesine 50mg Injection contains 'Tigecycline,' a broad-spectrum glycylcycline antibiotic that treats bacterial infections, such as abdominal infections, community-acquired pneumonia (lung infection), and complicated skin and skin structure infections. It works by preventing the synthesis of bacterial proteins, which are the primary cursors for carrying out bacteria's vital functions. Tigecycline is bacteriostatic and inhibits bacterial reproduction.

Directions for Use

Tigesine 50mg Injection will be administered by a healthcare professional; do not self-administer it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tigesine 50mg Injection

  • Nausea 
  • Vomiting 
  • Diarrhoea 
  • Headache
  • Abnormal liver function tests 

Drug Warnings

Let your doctor know if you have any kidney or liver diseases, colitis (inflammation of the inner lining of the colon), and pancreatitis. Clostridium difficile-associated diarrhoea (CDAD) is reported during usage of antibiotics like Tigesine 50mg Injection. Therefore, please undergo an examination to rule out the chances of CDAD if you experience diarrhoea following Tigecycline therapy. Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since Tigesine 50mg Injection may affect vaccines' activity. Tigesine 50mg Injection may induce photosensitivity and makes your skin more sensitive to the sun; hence apply sunscreen when you step out. Tigesine 50mg Injection is not recommended during pregnancy due to its harmful effects on the baby. Please seek medical advice if you are breastfeeding before taking Tigesine 50mg Injection. Tigesine 50mg Injection causes dizziness; hence drive or operate machinery only when you are alert. Tigesine 50mg Injection is not recommended in children below eight years of age. 

Drug Interactions

Drug-Drug Interaction: Tigesine 50mg Injection may interact with anticoagulants (warfarin) and decrease the efficacy of oral contraceptives. 

Drug-Food Interaction: Avoid alcohol intake while using Tigesine 50mg Injection.

Drug-Disease Interaction: Before taking Tigesine 50mg Injection, let your doctor know if you have any kidney or liver diseases, colitis and pancreatitis.

Drug-Drug Interactions Checker List

  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Include more fibre enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. 
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Tigesine 50mg Injection properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Tigesine 50mg Injection. 
  • Avoid intake of alcoholic beverages with Tigesine 50mg Injection as it can make you dehydrated and affect your sleep. This can make it more challenging for your body to aid the Tigesine 50mg Injection in fighting off infections.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Do not walk barefoot at places like gym showers to prevent bacterial infections. 

Special Advise

  • Inform your doctor and laboratory staff in advance that you take Tigesine 50mg Injection if you are undergoing any medical examinations. Tigesine 50mg Injection can cause abnormal liver function test results.
  • Renal, liver function and blood tests are advised during prolonged therapy to rule out any toxicity caused due to overdose of Tigesine 50mg Injection. 
  • Clostridium difficile associated diarrhoea (CDAD) is reported during the usage of antibiotics like Tigecycline. Please see your doctor if you experience prolonged diarrhoea.

Disease/Condition Glossary

Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod and spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever and tiredness. 

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Alcohol

Caution

Avoid taking alcohol while using Tigesine 50mg Injection since it may worsen the side effects.

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Pregnancy

Unsafe

Tigesine 50mg Injection is not recommended during pregnancy due to its harmful effects on the baby, including toxic effects on skeletal formation. Please consult your doctor before taking Tigesine 50mg Injection if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Tigesine 50mg Injection is excreted into breast milk. Please consult your doctor before taking Tigesine 50mg Injection if you are breastfeeding.

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Driving

Caution

You may experience dizziness as one of the side effects of Tigesine 50mg Injection. In such cases, do not drive or operate machinery until you feel better.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Tigesine 50mg Injection. Tigesine 50mg Injection should be used caution in cases of severe liver disease.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Tigesine 50mg Injection. Dose adjustment may be required.

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Children

Caution

Tigesine 50mg Injection is not recommended for children younger than eight years old.

Country of origin

India
Other Info - TI63879

FAQs

Tigesine 50mg Injection is used to treat bacterial infections like abdominal infections, community-acquired pneumonia (lung infection), and complicated skin and skin structure infections.
Tigesine 50mg Injection contains Tigecycline, a broad-spectrum antibiotic that treats various bacterial infections. It works by inhibiting bacterial protein synthesis, which further inhibits bacterial growth.
Tigesine 50mg Injection can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start Tigesine 50mg Injection if you are undergoing any vaccinations.
Tigesine 50mg Injection can make your skin more sensitive to the harmful effects of sunlight. Hence it is advised to use sunscreen and wear protective clothing while using Tigesine 50mg Injection. It is also recommended to avoid tanning booths and sunlamps.
Diarrhoea can be a side-effect of Tigesine 50mg Injection. Drink enough fluids and eat fibre rich food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.
Tigesine 50mg Injection will be administered by a healthcare professional; do not self-administer.
Yes, Tigesine 50mg Injection contains Tigecycline which belongs to the glycylcycline class of antibiotics.
Tigesine 50mg Injection is used to treat bacterial infections; it is not known if it is effective for covid-19. Please consult the doctor if you have any concerns.
Tigesine 50mg Injection starts working within 30-60 minutes. However, it might take a few days to notice its full effects.
Tigesine 50mg Injection may cause side effects like nausea, vomiting, diarrhoea, headache, and abnormal liver function tests. If any of these effects persist or worsen, seek medical advice promptly.

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