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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
TESTOFIL DEPOT INJECTION 4ML is used for androgen hormone replacement in men. It contains Testosterone, which helps replenish the deficient testosterone levels in adult men. Thereby, it helps in treating deficiency/absence of endogenous testosterone. Testosterone is the anabolic steroid and primary sex hormone in males, which plays an important role in developing male reproductive tissues like the prostate and testes.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About TESTOFIL DEPOT INJECTION 4ML

TESTOFIL DEPOT INJECTION 4ML belongs to a group of medicines called androgens indicated for testosterone replacement therapy in adult men for conditions associated with a deficiency/absence of endogenous testosterone, such as primary hypogonadism and hypogonadotropic hypogonadism. 
 
TESTOFIL DEPOT INJECTION 4ML contains Testosterone, which helps replenish the deficient testosterone levels in adult men. Thereby, TESTOFIL DEPOT INJECTION 4ML helps in treating deficiency/absence of endogenous testosterone. Testosterone is the anabolic steroid and primary sex hormone in males, which plays an important role in developing male reproductive tissues like the prostate and testes.
 
TESTOFIL DEPOT INJECTION 4ML will be administered by a healthcare professional; do not self-administer. In some cases, you may experience side effects such as injection site reactions, polycythemia (high number of red blood cells), headache, and depression. You are advised to talk to your doctor if the side effects persist or worsen.
 
Let your doctor know if you are allergic to any of the components in TESTOFIL DEPOT INJECTION 4ML. Do not use TESTOFIL DEPOT INJECTION 4ML if you are pregnant or breastfeeding. TESTOFIL DEPOT INJECTION 4ML is not recommended for children below 12 years as safety and effectiveness have not been established. Keep your doctor informed about your health conditions and medications to rule out any side effects/interactions.

Uses of TESTOFIL DEPOT INJECTION 4ML

Used for androgen hormone replacement in men

Medicinal Benefits

TESTOFIL DEPOT INJECTION 4ML belongs to a group of medicines called androgens indicated for testosterone replacement therapy in adult men for conditions associated with a deficiency/absence of endogenous testosterone. TESTOFIL DEPOT INJECTION 4ML contains Testosterone, which helps replenish the deficient testosterone levels in adult men. Thereby, TESTOFIL DEPOT INJECTION 4ML helps in treating deficiency/absence of endogenous testosterone. 

Directions for Use

TESTOFIL DEPOT INJECTION 4ML will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TESTOFIL DEPOT INJECTION 4ML

  • Injection site reactions 
  • Polycythemia (high number of red blood cells)
  • Headache
  • Depression

Drug Warnings

Do not take TESTOFIL DEPOT INJECTION 4ML if you are allergic to any of its contents; or if you have prostate cancer or breast cancer. TESTOFIL DEPOT INJECTION 4ML is not intended for use in women. Inform your doctor if you have a high blood cell count or high haemoglobin laboratory value, urinary problems due to an enlarged prostate, heart problems, diabetes, sleep apnoea (breathing problem while sleeping), or liver or kidney problems. TESTOFIL DEPOT INJECTION 4ML is not recommended for children below 12 years as safety and effectiveness have not been established. 

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking anti-diabetic medicines (insulin), anti-hypertensives (propranolol), oral anticoagulants/blood thinners, and corticosteroids.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have prostate cancer, urinary problems due to an enlarged prostate, or heart problems.

Drug-Drug Interactions Checker List

  • PROPRANOLOL

Habit Forming

Yes

Diet & Lifestyle Advise

  • Tuna, egg yolks, fortified cereals, oysters, shell fish, and beans are good sources of Testosterone.

  • Maintain a healthy diet and exercise regularly.

  • Get ample rest and proper sleep.

  • Reduce stress levels by doing yoga or meditation. 

  • Consume foods that are rich in zinc, such as nuts, crab, beans, lobster, and whole grains.

Special Advise

  • Regular monitoring of blood pressure, blood sugar levels, red blood cell count, and haemoglobin levels is advised.

  • Consult your doctor if you notice any signs and symptoms of a blood clot in your leg, such as pain, swelling or redness or signs and symptoms of a blood clot in your lungs, like difficulty breathing or chest pain.

  • Consult your doctor immediately if you have changes in mood or depression.

Disease/Condition Glossary

Testosterone replacement therapy: Testosterone replacement therapy, also known as androgen replacement therapy, is used to treat low levels of testosterone. Testosterone is the anabolic steroid and primary sex hormone in males, which plays an important role in the development of male reproductive tissues like the prostate and testes. Symptoms of low testosterone include reduced sex drive, erectile dysfunction, low/zero sperm count, loss of pubic/armpit hair, shrinking testicles, and hot flushes.

Primary hypogonadism: Primary hypogonadism is a condition in which the gonads (testes in men and ovaries in women) produce insufficient sex hormones. Sex hormones are responsible for secondary sexual characteristics, such as testicular development in men and breast development in women. Autoimmune disorders, genetic disorders, severe infections, pituitary disorders, and inflammatory diseases could be the causes of hypogonadism. Symptoms of hypogonadism include abnormal breast growth, erectile dysfunction, muscle loss, loss of body hair, osteoporosis, low sex drive, infertility, fatigue, hot flushing, and difficulty concentrating.

Hypogonadotropic hypogonadism: It is a form of hypogonadism that occurs due to a problem with the hypothalamus or pituitary gland. It is caused due to lack of the gonadotropin-releasing hormone, follicle-stimulating hormone (FSH), and luteinising hormone (LH). Damage to the pituitary gland, genetic defects, high prolactin levels, severe stress, nutritional problems, and certain medical conditions could be the causes of hypogonadotropic hypogonadism. 

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Alcohol

Consult your doctor

It is unknown if alcohol interacts with TESTOFIL DEPOT INJECTION 4ML. Please consult your doctor.

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Pregnancy

Not applicable

TESTOFIL DEPOT INJECTION 4ML is not indicated for use in women.

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Breast Feeding

Not applicable

TESTOFIL DEPOT INJECTION 4ML is not indicated for use in women.

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Driving

Caution

It is not known if TESTOFIL DEPOT INJECTION 4ML affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Please inform your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please inform your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

TESTOFIL DEPOT INJECTION 4ML is not recommended in children below 12 years as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - TES0033

Author Details

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FAQs

TESTOFIL DEPOT INJECTION 4ML helps in replenishing the deficient testosterone levels in adult men. Thereby helping treat deficiency/absence of endogenous testosterone.
TESTOFIL DEPOT INJECTION 4ML should be used with caution in patients with benign prostatic hyperplasia (BPH) as they are at an increased risk for worsening of signs and symptoms of BPH.
TESTOFIL DEPOT INJECTION 4ML might increase the risk of prostate cancer. It is recommended to evaluate patients for prostate cancer prior to initiating and during the treatment with TESTOFIL DEPOT INJECTION 4ML.
TESTOFIL DEPOT INJECTION 4ML may cause changes in anticoagulant activity. Therefore, frequent monitoring of prothrombin time and International Normalised Ratio (INR) is advised.
TESTOFIL DEPOT INJECTION 4ML may cause venous thromboembolism (formation of a blood clot in the vein), including deep vein thrombosis (blood clot develops in a deep vein) and pulmonary embolism (blockage in the lung artery). Consult your doctor if you experience pain, oedema (swelling), warmth, and erythema (skin redness) in lower proximity or shortness of breath.

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