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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

TELBIHEP TABLET is an antiviral medicine used to treat chronic Hepatitis B infection. It contains Telbivudine, which belongs to the class of nucleoside analogues. It works by blocking the activity of the hepatitis B virus DNA Polymerase enzyme in the liver cells. This causes DNA termination and reduces the amount of hepatitis B virus in the body. It is not recommended for children below 16 years of age as efficacy and safety have not been established.

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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About TELBIHEP TABLET

TELBIHEP TABLET is an antiviral medicine used to treat viral infections. TELBIHEP TABLET is used in the treatment of chronic Hepatitis B infection in patients with evidence of viral replication. It is a serious infection caused by the Hepatitis B virus. It is a contagious infection that spreads from person to person and affects the liver. TELBIHEP TABLET is only used in treating the infection. It does not cure or prevent further liver complications.

TELBIHEP TABLET contains Telbivudine, a nucleoside analogue. It works by blocking the activity of the hepatitis B virus DNA Polymerase enzyme in liver cells. This causes DNA termination and reduces the amount of hepatitis B virus in the body.

TELBIHEP TABLET may cause certain side effects such as headache, abdominal pain, nausea, diarrhoea, dizziness, vomiting, cough, abdominal pain, fever, myalgia, back pain and fatigue. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. It should be taken with or after food to avoid any stomach upset. Use it as suggested by your doctor. Your doctor will decide the dose of the medicine based on your health condition.

TELBIHEP TABLET should be avoided if you are allergic to it. Caution should be exercised in conditions like liver cirrhosis, liver cancer, or kidney problems. TELBIHEP TABLET may cause lactic acidosis, severe hepatomegaly with steatosis, myopathy, and peripheral neuropathy in some patients. Stopping the treatment with TELBIHEP TABLET may lead to acute exacerbations of Hepatitis B infection. Hence, careful monitoring should be done during and after the treatment. If you are pregnant or breastfeeding, inform your doctor before starting treatment with this medicine. TELBIHEP TABLET is not recommended for children below 16 years of age as efficacy and safety have not been established.

Uses of TELBIHEP TABLET

TELBIHEP TABLET is used in the treatment of hepatitis B virus infection

Medicinal Benefits

TELBIHEP TABLET contains Telbivudine, which belongs to the class of nucleotide analogues. It works by blocking the activity of the hepatitis B virus DNA Polymerase enzyme in the liver cells, which is essential for the virus to grow. This causes DNA termination and, therefore, reduces the amount of hepatitis B virus in the body. This medicine only treats the HBV infection but does not cure it or prevent further liver complications.

Directions for Use

Tablet/Capsule: TELBIHEP TABLET is a prescription medicine. It should be taken only if prescribed by your doctor. It should be taken with or after food to avoid stomach upset. Swallow the medicine as a whole with a glass of water. Do not chew, break, or crush the medicine.Oral Solution: Take TELBIHEP TABLET as prescribed by your doctor. Measure the required amount of medicine into the measuring cup and then swallow it. It is advised to close the cap of the bottle tightly after each use.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TELBIHEP TABLET

  • Headache
  • Abdominal pain
  • Nausea
  • Diarrhoea
  • Vomiting
  • Tiredness
  • Trouble sleeping
  • Fatigue
  • Back pain
  • Dizziness
  • Cough
  • Myalgia
  • Fever
  • Sore throat

Drug Warnings

Avoid taking TELBIHEP TABLET and inform your doctor if you are allergic to it. Keep your doctor informed about your complete medical history to rule out any serious side effects. If you are pregnant or breastfeeding, inform your doctor before starting treatment with this medicine. Caution should be exercised in patients having underlying conditions like liver cirrhosis, HIV infection, liver cancer, or kidney problems before starting the treatment. TELBIHEP TABLET may cause lactic acidosis, severe hepatomegaly with steatosis, myopathy, peripheral neuropathy and acute exacerbations of Hepatitis B, HIV infection, lactic acidosis and severe hepatomegaly with steatosis, as it may cause serious side effects. It is advised not to stop taking TELBIHEP TABLET abruptly, as it can cause a recurrence of severe acute exacerbations of hepatitis or may also lead to cirrhosis. TELBIHEP TABLET is not recommended for children below 16 years of age as efficacy and safety have not been established. TELBIHEP TABLET should not be taken along with pegylated interferon alfa-2a as it can cause peripheral neuropathy. Hence, informing your doctor about your complete medication history before taking this medicine is advised.

Drug Interactions

Drug-Drug Interactions: TELBIHEP TABLET may interact with immunomodulators (interferon alpha-2a), antibiotics (vancomycin), vitamins, minerals, etc.

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have any history of liver or kidney disease, cirrhosis, and liver cancer.

Drug-Drug Interactions Checker List

  • INTERFERON ALFA
  • VANCOMYCIN
  • AMPHOTERICIN B

Habit Forming

No

Diet & Lifestyle Advise

  • Eat more vegetables, fruits, and whole grains such as brown rice, oats, quinoa, and barley.
  • Include healthy fats like avocados, olive oil, and nuts.
  • Drink plenty of water for better processing of food by the body.
  • Avoid sugary foods such as cake, cookies, packaged baked goods, and soda. Also, avoid heavy-salt foods.
  • Avoid foods containing saturated fats such as fried foods, fatty cuts of meat, sour cream, and butter.
  • Try to eat low-fat or non-fat dairy products to minimize damage to the liver.

Special Advise

  • Sudden withdrawal of TELBIHEP TABLET should be avoided as it can cause severe acute exacerbations of hepatitis or other serious side effects.
  • Frequent monitoring of liver and kidney function tests are required while on treatment with TELBIHEP TABLET to monitor liver and kidney functions.
  • Patients should be observed carefully for any changes in the liver function test even after the completion of the treatment course.

Disease/Condition Glossary

Hepatitis B Virus Infection: It is a serious contagious infection caused by the Hepatitis B virus affecting the liver. It can be an acute (an infected person may be sick for only a few days) or chronic infection (it develops slowly but progresses to a serious lifelong infection). This infection spreads from person to person through blood contact (being pricked with a contaminated needle, using a razor), intimate contact with the infected person, direct contact with infected blood, or contact with any other personal items with leftovers of infected fluid or even from mother to baby during birth. TELBIHEP TABLET is used to treat HBV infection.

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Alcohol

Unsafe

Alcohol intake might increase the risk of side effects. Hence, avoid alcohol consumption while on treatment with TELBIHEP TABLET.

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Pregnancy

Caution

Limited data is available on the effect of TELBIHEP TABLET in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking TELBIHEP TABLET. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data are available on the effect of TELBIHEP TABLET on breastfeeding. Hence, if you are a nursing mother, inform your doctor before taking TELBIHEP TABLET. Your doctor may suggest you stop breastfeeding while taking TELBIHEP TABLET.

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Driving

Unsafe

TELBIHEP TABLET may cause dizziness as a side effect. Hence, do not drive or operate heavy machinery until you are not alert or during the treatment.

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Liver

Caution

TELBIHEP TABLET has not been studied in patients with decompensated liver disease or liver transplant recipients. Hence, if you have liver problems, inform your doctor before using TELBIHEP TABLET.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking TELBIHEP TABLET. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

TELBIHEP TABLET is not recommended for use in children, as efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - TEL0334

FAQs

TELBIHEP TABLET is used to treat Hepatitis B Virus infection.
TELBIHEP TABLET contains Telbivudine, which works by blocking the activity of the hepatitis B virus DNA Polymerase enzyme in the liver cells. This causes DNA termination and reduces the amount of hepatitis B virus in the body.
Stopping treatment with TELBIHEP TABLET may worsen Hepatitis B infection. Close monitoring is necessary even after completion of the treatment course. Consult your doctor if you have concerns.
TELBIHEP TABLET can be taken with or after food as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not chew, break, or crush it.
Yes, TELBIHEP TABLET is effective if used as per dose and duration advised by the doctor. Do not exceed the recommended dose. Continue using TELBIHEP TABLET for the prescribed duration. Follow your doctor’s instructions.
Drug resistance is the reduction in effectiveness of a medication by disease-causing organisms, such as bacteria, viruses, or fungi. TELBIHEP TABLET can cause drug resistance, but it's relatively uncommon. Resistance is more likely to occur if TELBIHEP TABLET is not taken exactly as prescribed, such as missing doses or not completing the full course of treatment. To minimize the risk of developing resistance, follow your doctor's instructions carefully and take TELBIHEP TABLET exactly as prescribed by your doctor.
The duration of treatment with TELBIHEP TABLET can vary depending on individual and the patient's response to TELBIHEP TABLET. Therefore, continue using TELBIHEP TABLET as prescribed by your doctor. Do not skip any dose.
If you forget to take a dose of TELBIHEP TABLET, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dose. Do not double the dose to make up for the missed one.
In HBV patients who are diagnosed with HIV, TELBIHEP TABLET is not recommended until and unless these patients start taking medicines for HIV management. Therefore, please consult your doctor for effective treatment.
No, there is no cure for hepatitis B. TELBIHEP TABLET does not cure hepatitis B but helps to improve liver condition. However, if you have any concerns, discuss with your doctor.
The common side effects of TELBIHEP TABLET are headache, abdominal pain, nausea, diarrhoea, dizziness, vomiting, cough, abdominal pain, fever, myalgia (muscle pain or soreness), back pain and fatigue. If any of these side effects persist or worsen, please consult your doctor.

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