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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Tegafi Capsule is an anti-cancer medicines indicated for first-line treatment of metastatic colorectal cancer. It contains Tegafur and Uracil, which work by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer. In some cases, this medication may cause side effects such as diarrhoea, nausea, vomiting, and abdominal pain. This medicine is not recommended for children as safety and effectiveness have not been established.

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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Tegafi Capsule

Tegafi Capsule belongs to the group of anti-cancer medicines indicated with calcium folinate for the first-line treatment of metastatic colorectal cancer. Colorectal cancer is a disease in which the cells in the colon or rectum grow out of control.

Tegafi Capsule contains Tegafur and Uracil, which work by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer.

In some cases, Tegafi Capsule may cause side effects such as diarrhoea, nausea, vomiting, and abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not take Tegafi Capsule if you are pregnant or breastfeeding. This medicine is not recommended for children as safety and effectiveness have not been established. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Tegafi Capsule

Treatment of Colorectal cancer

Medicinal Benefits

Tegafi Capsule belongs to the group of anti-cancer medicines indicated for the first-line treatment of metastatic colorectal cancer with calcium folinate. Tegafi Capsule contains Tegafur and Uracil, which work by interfering with the growth and multiplication of cancer cells. Thus, it helps treat cancer.

Directions for Use

Take the medicine an hour before or after food or as advised by the doctor. Swallow the medicine as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tegafi Capsule

  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Asthenia (weakness)
  • Stomatitis/mucositis (inflammation in mouth)

Drug Warnings

Do not take Tegafi Capsule if you are allergic to any of its components or if you are pregnant or breastfeeding. Consult the doctor immediately if you become pregnant during treatment with Tegafi Capsule . Tegafi Capsule is not recommended for children, paediatrics and adolescents. Inform the doctor if you experience symptoms of infection (fever or sudden unwell feeling), unexplained bleeding or bruising (bleeding gums, nose bleeds, rashes or blood spots on the skin), anaemia (tiredness and breathlessness) or conjunctivitis (sore and inflamed eyes). Let the doctor know if you take other medicines, including supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water to stay hydrated.

Special Advise

Tegafi Capsule may harm the developing baby. Therefore, it is not advisable to become pregnant or father a child during treatment with Tegafi Capsule . Use effective contraception during treatment and for a few months afterwards.

Disease/Condition Glossary

Colorectal cancer: It is a cancer of the colon or rectum. Colorectal cancer is the growth of cells in the lower end of the digestive tract. Most of these cancers begin as polyps (non-cancerous growths). Symptoms may include abdominal discomfort, blood in the stool, and changes in bowel habits like constipation or diarrhoea.

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Alcohol

Consult your doctor

It is not known if alcohol affects Tegafi Capsule . Please consult your doctor.

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Pregnancy

Unsafe

Tegafi Capsule is not recommended during pregnancy as it may cause foetal harm. Women with childbearing potential are advised to avoid becoming pregnant during treatment with Tegafi Capsule .

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Breast Feeding

Unsafe

This medicine may pass into breast milk. Breastfeeding is not recommended during treatment with Tegafi Capsule and for a few months afterwards.

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Driving

Caution

Tegafi Capsule may cause tiredness. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Caution

When Tegafi Capsule is used, patients with mild to moderate hepatic dysfunction should be closely monitored by liver function tests.

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Kidney

Consult your doctor

In patients with renal impairment, Tegafi Capsule has not been used extensively. When using this medicine in such patients, physicians ought to proceed with caution.

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Children

Unsafe

Tegafi Capsule is not recommended for children as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TEG0092

Author Details

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FAQs

Tegafi Capsule is used to treat Colorectal cancer.
Tegafi Capsule works by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer.
Tegafi Capsule may cause diarrhoea in some cases. Drink plenty of fluids if you have diarrhoea. Consult the doctor if you experience severe diarrhoea; your doctor may initiate supportive care or interrupt medication based on your condition. In patients with severe diarrhoea, careful monitoring and fluid and electrolyte replacement are recommended to prevent dehydration.
Tegafi Capsule may reduce the number of white blood cells, which help fight infections. This might increase the risk of infections. Consult the doctor if you experience symptoms of infection, such as a fever, or if you suddenly feel unwell.
Tegafi Capsule may affect your ability to become pregnant or father a child. Prior to the start of the treatment, discuss with your doctor if you have any concerns about fertility.

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