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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:32 PM IST
Tamoxifen Citrate 20 mg Tablet is used to treat breast cancer. It contains Tamoxifen which works by blocking the effects of oestrogen that is required for the cancer cells to grow. In some cases, this medicine may cause side effects such as hot flashes, headache, tiredness, nausea, and numbness or tingling sensation. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

TAMOXIFEN-20MG

Manufacturer/Marketer

Fresenius Kabi India Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Tamoxifen Citrate 20 mg Tablet

Tamoxifen Citrate 20 mg Tablet belongs to the class of 'anti-neoplastic agents', primarily used to treat breast cancer. It is also used to treat infertility caused by a failure in the ovulation (produce and release) process in women. Breast cancer is a type of cancer in the breast cells stimulated by a female sex hormone called oestrogen.

Tamoxifen Citrate 20 mg Tablet contains Tamoxifen, which belongs to the class of 'anti oestrogens. Some types of breast cancers need oestrogen (female sex hormone) to grow. Tamoxifen Citrate 20 mg Tablet blocks the effects of this oestrogen, thus helping in treating breast cancer. Tamoxifen Citrate 20 mg Tablet is also used to reduce the risk of occurrence of breast cancer in women due to age and personal and family medical history.

Use Tamoxifen Citrate 20 mg Tablet as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Tamoxifen Citrate 20 mg Tablet include hot flashes, headache, muscle aches, leg cramps, tiredness, nausea, thinning of hair and numbness or tingling sensation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not take or stop this medicine if the doctor did not advise you to do so. Before starting Tamoxifen Citrate 20 mg Tablet , let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, high cholesterol levels, high blood pressure, diabetes, history of stroke or blood clot, receiving chemotherapy, and cataracts. Tamoxifen Citrate 20 mg Tablet is not indicated for use in pregnant and breastfeeding women. Tamoxifen Citrate 20 mg Tablet may make you feel tired; hence, drive when you are alert only. It is not recommended to consume alcohol along with Tamoxifen Citrate 20 mg Tablet . Tamoxifen Citrate 20 mg Tablet is not recommended for children below two years of age.

Uses of Tamoxifen Citrate 20 mg Tablet

Treatment of Breast cancer.

Medicinal Benefits

Tamoxifen Citrate 20 mg Tablet contains Tamoxifen, which is an anti-oestrogen drug. It treats breast cancer that has spread to other parts of the body in men and women. Tamoxifen Citrate 20 mg Tablet is also used to treat breast cancer in women who are earlier treated with surgery, radiation, and chemotherapy. It effectively treats infertility caused by failure in the ovulation (produce and release) process in women. Some types of breast cancers need oestrogen (female sex hormone) to grow. Tamoxifen Citrate 20 mg Tablet blocks the effects of this oestrogen, thus helps in treating breast cancer. Tamoxifen Citrate 20 mg Tablet is also used to reduce the risk of occurrence of breast cancer in women due to age, personal and family medical history.

Directions for Use

Swallow the medicine as a whole with a glass of water. You can take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tamoxifen Citrate 20 mg Tablet

  • Hot flashes

  • Headache

  • Muscle aches

  • Tiredness

  • Leg cramps

  • Nausea

  • Thinning of hair

  • Numbness or tingling sensation

Drug Warnings

Inform your doctor if you have any allergic reactions to Tamoxifen Citrate 20 mg Tablet or other medications. Before starting Tamoxifen Citrate 20 mg Tablet , let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, high cholesterol levels, high blood pressure, diabetes, history of stroke or blood clot, receiving chemotherapy, and cataracts. Tamoxifen Citrate 20 mg Tablet can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, Tamoxifen Citrate 20 mg Tablet is not indicated for use in pregnancy and breastfeeding women. If you are using Tamoxifen Citrate 20 mg Tablet , make sure to use reliable contraception forms to prevent pregnancy during the course. Tamoxifen Citrate 20 mg Tablet can make you feel tired and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with Tamoxifen Citrate 20 mg Tablet . Tamoxifen Citrate 20 mg Tablet is not recommended for children younger than two years of age.

Drug Interactions

Drug-Drug Interaction: Tamoxifen Citrate 20 mg Tablet may interact with other drugs treating breast cancer (letrozole, anastrozole, exemestane), blood thinners (warfarin), anti-cancer drugs, antibiotics (rifampin), antidepressants (fluoxetine, paroxetine), fits medicines (carbamazepine, phenobarbital, phenytoin, primidone), anti-ulcer drugs (cimetidine), smoking cessation aids (bupropion), heart-related drugs (quinidine), and drugs treating hyperparathyroidism/overactive parathyroid gland (cinacalcet).

Drug-Food Interaction: Grapefruit and its juice may interact with Tamoxifen Citrate 20 mg Tablet .

Drug-Disease Interaction: Tamoxifen Citrate 20 mg Tablet should be used with caution in cases of liver or kidney diseases, heart diseases, high cholesterol levels, high blood pressure, diabetes, history of stroke or blood clot, receiving chemotherapy, and cataracts.

Drug-Drug Interactions Checker List

  • LETROZOLE
  • ANASTROZOLE
  • EXEMESTANE
  • WARFARIN
  • RIFAMPIN
  • FLUOXETINE
  • PAROXETINE
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CIMETIDINE
  • BUPROPION
  • QUINIDINE
  • CINACALCET

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.

  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.

  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.

  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.

  • Eat at regular intervals.

  • Keep your weight under control with BMI of 19.5-24.9.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Special Advise

  • Your doctor may advise regular physical exams and mammograms.

  • Self-examine your breasts to check for any lumps monthly while using Tamoxifen Citrate 20 mg Tablet .

  • Your doctor may also advise liver function tests to monitor your liver health.

  • Tamoxifen may interfere with specific tests like thyroid tests. Hence, it is important to inform your doctor or laboratory staff that you use Tamoxifen Citrate 20 mg Tablet before undergoing any medical examinations.

Disease/Condition Glossary

Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes, a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm. 

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Alcohol

Unsafe

It is unsafe to consume alcohol while using Tamoxifen Citrate 20 mg Tablet . Please consult your doctor for more information.

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Pregnancy

Unsafe

Tamoxifen Citrate 20 mg Tablet is a pregnancy category D drug. It is unsafe to use Tamoxifen Citrate 20 mg Tablet in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using Tamoxifen Citrate 20 mg Tablet .

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Breast Feeding

Unsafe

Tamoxifen Citrate 20 mg Tablet is not recommended to use during breastfeeding since it may be unsafe for the breastfed infant. Please seek medical advice if you are a nursing mother before starting Tamoxifen Citrate 20 mg Tablet .

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Driving

Unsafe

Tamoxifen Citrate 20 mg Tablet causes tiredness and may affect your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Tamoxifen Citrate 20 mg Tablet .

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment before starting Tamoxifen Citrate 20 mg Tablet .

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Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting Tamoxifen Citrate 20 mg Tablet .

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Children

Caution

Tamoxifen Citrate 20 mg Tablet is not recommended in children younger than two years of age.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi AG? , Else-Kröner-Straße 1 ? , 61352 Bad Homburg , Germany
Other Info - TAM0007

Author Details

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FAQs

Tamoxifen Citrate 20 mg Tablet is primarily used to treat breast cancer. It is also used to treat infertility caused by a failure in the ovulation (produce and release) process in women.
Tamoxifen Citrate 20 mg Tablet contains Tamoxifen, an anti-neoplastic agent. It blocks the effects of the female sex hormone called oestrogen. This process of inhibiting the hormone's action can decrease cancer cells' growth in breast cancer.
Tamoxifen Citrate 20 mg Tablet should be used with caution and under doctor's supervision only if you have any medical history of liver or kidney diseases, heart diseases, high cholesterol levels, high blood pressure, diabetes, history of stroke or blood clot, receiving chemotherapy, and cataracts. Let your doctor know if you have any other medical concerns before using Tamoxifen Citrate 20 mg Tablet .
During treatment with Tamoxifen Citrate 20 mg Tablet , it is essential to look for any signs of a stroke (slurred speech, sudden weakness or numbness, severe headache), signs of a blood clot in the lung (chest pain, sudden coughing, wheezing, rapid breathing, coughing up blood), and signs of a blood clot in one or both legs (pain, swelling, warmth, redness). If you further notice any symptoms that are not manageable or unusual, please seek prompt medical advice.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
Swallow the medicine as a whole with a glass of water. You can take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it. The dose of Tamoxifen Citrate 20 mg Tablet will be suggested by your doctor based on your condition.
Take the missed dose as soon as you remember. If it's almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one. If you are unsure about what to do, consult your pharmacist for guidance.
Do not stop taking Tamoxifen Citrate 20 mg Tablet as it may increase the risk or progression of the cancer. It is advised to complete the course prescribed by your doctor. However, if you face any difficulty while taking Tamoxifen Citrate 20 mg Tablet consult your doctor immediately.
The common side effects of Tamoxifen Citrate 20 mg Tablet include hot flashes, headache, muscle aches, leg cramps, tiredness, nausea, thinning of hair and numbness or tingling sensation. Not everyone experiences these side effects, and they can vary from person to person. If the side effects persist or worsen, please consult your doctor.

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