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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Taftrio Tablet is an antiretroviral medicine used in the treatment of HIV. It contains Bictegravir, Emtricitabine and Tenofovir. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. This medicine helps reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV.

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Manufacturer/Marketer

Hetero Healthcare Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-26

for this medicine

About Taftrio Tablet

Taftrio Tablet is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS).

Taftrio Tablet contains Bictegravir, Emtricitabine and Tenofovir as key ingredients. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction.

Taftrio Tablet may cause side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, fatigue, diarrhoea, myalgia (muscle pain), skin rash and other allergic reactions. If these side effects persist, please consult your doctor. Taftrio Tablet should be taken as advised by your doctor.

Taftrio Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with Hepatitis B infection and severe hepatic impairment. Before taking this medicine, inform your doctor if you have liver/kidney disease, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If you are pregnant and breastfeeding, let your doctor know before taking Taftrio Tablet . Taftrio Tablet should be used in children only if recommended by the doctor.

Uses of Taftrio Tablet

Treatment of Human Immunodeficiency Virus (HIV) Infection

Medicinal Benefits

Taftrio Tablet is a combination of Bictegravir, Emtricitabine and Tenofovir. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. Taftrio Tablet helps reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Directions for Use

Take Taftrio Tablet as advised by your doctor. It can be taken with or without food. Swallow as a whole with a glass of water. Do not chew, crush, or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Taftrio Tablet

  • Nausea
  • Abdominal pain
  • Vomiting
  • Joint ache
  • Fatigue
  • Loss of appetite
  • Myalgia
  • Skin rash
  • Diarrhoea
  • Headache
  • Dizziness

Drug Warnings

Taftrio Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with severe hepatic impairment, hepatitis B infection and a combination of other HIV medicines. Inform your doctor about your medical history and the medicines you take to prevent possible interactions. Taftrio Tablet is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. If the patient develops any signs or symptoms of hepatitis, increased transaminase, rash, or hypersensitivity reactions, Taftrio Tablet should be discontinued immediately. This medicine may cause dizziness; hence, avoid driving or operating machines while taking Taftrio Tablet . Before taking this medicine, inform your doctor if you have liver/kidney diseases, hypersensitivity reactions, Stevens-Johnson syndrome, cirrhosis, or hepatic fibrosis. If pregnant and breastfeeding, inform your doctor before taking Taftrio Tablet . Taftrio Tablet should be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. Taftrio Tablet treats the infection but does not cure or prevent it.

Drug Interactions

Drug-Drug Interactions: Taftrio Tablet may interact with contraceptives (ethyl estradiol, norethindrone), anti-viral drugs (adefovir dipivoxil, atazanavir, lamivudine), anti-Tb drug (rifampicin), ulcer medicine (sucralfate), antibiotics (azithromycin, clarithromycin, rifabutin), immunosuppressants (cyclosporine), anti-epileptics (phenobarbital or phenytoin), antacids, iron supplements and vitamins.

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have moderate to severe hepatic impairment, Stevens-Johnson syndrome, cirrhosis, hepatic fibrosis, and other skin disorders before starting treatment with Taftrio Tablet .

Drug-Drug Interactions Checker List

  • ADEFOVIR
  • ATAZANAVIR
  • RIFAMPICIN
  • SUCRALFATE
  • CLARITHROMYCIN
  • CYCLOSPORIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.  
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.

Special Advise

  • Get an HIV test done at least every three months.
  • Taftrio Tablet may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Taftrio Tablet should be carefully monitored throughout the treatment.
  • Periodic liver function and CBC tests are recommended while taking Taftrio Tablet .

Disease/Condition Glossary

HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. Taftrio Tablet helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Taftrio Tablet . Alcohol intake might increase the risk of stomach or intestine bleeding.

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Pregnancy

Caution

If you are pregnant or suspect you may be pregnant, inform your doctor before taking Taftrio Tablet . Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.

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Breast Feeding

Unsafe

Taftrio Tablet is excreted in milk. If you have HIV or are taking Taftrio Tablet , you should not breastfeed your baby.

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Driving

Unsafe

Avoid driving vehicles or operating machines after taking Taftrio Tablet as it may cause fatigue.

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Liver

Caution

Taftrio Tablet can result in serious, sometimes fatal, liver damage. Inform your doctor if you have or have had a liver illness, particularly hepatitis B or C. Your doctor will most likely advise you not to take Taftrio Tablet .

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Kidney

Caution

Before using Taftrio Tablet , inform your doctor if you have or have ever had kidney disease, particularly if you are on dialysis treatment.

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Children

Consult your doctor

Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.

Country of origin

India

Manufacturer/Marketer address

7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad - 500 018. Telangana, India
Other Info - TAF0029

FAQs

Taftrio Tablet is used to treat HIV Infection.
Taftrio Tablet works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction.
No, completing the treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.
Taftrio Tablet doesnot cure HIV infection. However, it helps to control the disease and prevent opportunistic infections. Taftrio Tablet is used in combination with other anti-retroviral medicines.

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