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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Syntran SB 130 Capsule is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ITRACONAZOLE-130MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Syntran SB 130 Capsule

Syntran SB 130 Capsule is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Syntran SB 130 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Take Syntran SB 130 Capsule as prescribed. Your doctor will advise you on how often you take Syntran SB 130 Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Syntran SB 130 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Syntran SB 130 Capsule or any other medicines, please tell your doctor. Syntran SB 130 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Syntran SB 130 Capsule . Do not take Syntran SB 130 Capsule if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Syntran SB 130 Capsule . Avoid taking fentanyl (a strong opioid narcotic medicine) with Syntran SB 130 Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Syntran SB 130 Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Syntran SB 130 Capsule

Treatment of Fungal infections

Medicinal Benefits

Syntran SB 130 Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Syntran SB 130 Capsule inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby weakening and damaging the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

Side Effects of Syntran SB 130 Capsule

  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Cough
  • Cold
  • Throat pain
  • Back pain
  • Stomach pain

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Syntran SB 130 Capsule with cola.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to Syntran SB 130 Capsule or any other medicines, please tell your doctor. Syntran SB 130 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Syntran SB 130 Capsule . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Syntran SB 130 Capsule , as it may cause severe breathing problems and can even lead to death. Do not take Syntran SB 130 Capsule if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Syntran SB 130 Capsule and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Syntran SB 130 Capsule .

Therapeutic Class

ANTIFUNGALS

Drug-Drug Interactions

verifiedApollotooltip
ItraconazoleAvanafil
Critical
ItraconazoleIsavuconazole
Critical

Drug-Food Interactions

verifiedApollotooltip
ITRACONAZOLE-130MGGrapefruit and Grapefruit Juice
Moderate

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

What if I have taken an overdose of Syntran SB 130 Capsule

Do not take more than the prescribed dose of Syntran SB 130 Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid consumption of alcohol with Syntran SB 130 Capsule as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Syntran SB 130 Capsule is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Syntran SB 130 Capsule .

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Breast Feeding

Caution

Syntran SB 130 Capsule is excreted in human milk and may harm the baby. Therefore, Syntran SB 130 Capsule is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Caution

Syntran SB 130 Capsule may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Syntran SB 130 Capsule .

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Liver

Caution

Take Syntran SB 130 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Syntran SB 130 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Syntran SB 130 Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai - 400 026.
Other Info - SYN0342

Author Details

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FAQs

Syntran SB 130 Capsule is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.
You are not recommended to take Syntran SB 130 Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Syntran SB 130 Capsule with other medicines.
No, Syntran SB 130 Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Syntran SB 130 Capsule and after 2 months of stopping treatment with Syntran SB 130 Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Syntran SB 130 Capsule .
Syntran SB 130 Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Syntran SB 130 Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Syntran SB 130 Capsule and consult a doctor immediately.
You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Syntran SB 130 Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Syntran SB 130 Capsule because antacids decrease the absorption and blood levels of Syntran SB 130 Capsule . However, please consult a doctor before taking other medicines with Syntran SB 130 Capsule .
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
You are not recommended to stop taking Syntran SB 130 Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Syntran SB 130 Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Syntran SB 130 Capsule , please consult your doctor.
Inform your doctor if you are sexually active and discuss effective contraception methods. Syntran SB 130 Capsule may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Syntran SB 130 Capsule .
Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Syntran SB 130 Capsule may interact with other medicines. Also, let your doctor know if you are stopping any medicine.
Syntran SB 130 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.
Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.
The side effects of Syntran SB 130 Capsule include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.
If you have taken overdose of Syntran SB 130 Capsule , please consult your doctor immediately.
Store Syntran SB 130 Capsule at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

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