Stresnil 0.25 mg Tablet is used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder. Insomnia is a sleeping disorder in which a person finds difficulty falling asleep or staying asleep. Due to anxiety and panic disorder, a person cannot sleep due to disturbances in their circadian cycle and hormonal imbalances in the brain, like melatonin. 

Stresnil 0.25 mg Tablet is a combination of two medicines, Alprazolam and Melatonin, which help a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime. 

Take Stresnil 0.25 mg Tablet with or without food and swallow whole with a glass of water. Do not break, crush, or chew it. Your doctor will advise you how often you take Stresnil 0.25 mg Tablet based on your medical condition. The most common side effects of Stresnil 0.25 mg Tablet include drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Most of these side effects of Stresnil 0.25 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Tell your doctor if you have an ongoing medical condition, including depression, diabetes, an autoimmune disorder, or high blood pressure. If you are known to be allergic to Stresnil 0.25 mg Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before taking Stresnil 0.25 mg Tablet . Stresnil 0.25 mg Tablet should be used with caution in elderly patients as there is an increased risk of adverse reactions such as dizziness, muscle weakness, and drowsiness.

Stresnil 0.25 mg Tablet belongs to a class of sedatives and hypnotics, primarily used to treat insomnia (difficulty in falling asleep or staying asleep). Stresnil 0.25 mg Tablet is a combination of two medicines: 'Alprazolam' and  'Melatonin', which helps a person fall asleep faster and stay asleep during the night, which has been disturbed due to anxiety or panic disorder. Stresnil 0.25 mg Tablet helps relax the brain's exciting chemicals (GABA), allowing a person to sleep easily and stay asleep during the whole night without any disturbance.  

• Tiredness
• Dizziness
• Headache
• Drowsiness
• Stomach pain
• Depressed mood

Before your doctor prescribes your Stresnil 0.25 mg Tablet , you should tell your doctor if you have allergies or not. With it, also tell if you are pregnant or breastfeeding as the use of this medication is restricted to be used in pregnancy and breastfeeding. Elderly people are more responsive to the side effects of the drug, so they should tell every product, including the herbal ones to their doctor so that doctor can decide the dosage for them. Inform your doctor about myasthenia gravis (muscle weakness), drug addiction, chronic pulmonary insufficiency, narrow-angle glaucoma, and kidney/liver problem before taking Stresnil 0.25 mg Tablet . Do not take Stresnil 0.25 mg Tablet with opioids as it may cause breathing problems, drowsiness and coma.

Drug-Drug Interactions: Stresnil 0.25 mg Tablet may interact with anti-depressants (fluoxetine, fluvoxamine, nefazodone), antibiotics (erythromycin, rapamycin), antifungals (ketoconazole), anti-HIV drugs (delavirdine), pain killers (morphine, codeine, dihydrocodeine, buprenorphine). 

Drug-Food Interactions: Foods, including grapefruit juice, may worsen the side effects of the medicine (such as sleepiness or slowed breathing). Avoid taking such foods that can affect the action of Stresnil 0.25 mg Tablet .

Drug-Disease Interactions: The possible disease interaction include acute alcohol intoxication, closed-angle glaucoma, drug dependence, kidney/liver disease, respiratory depression, seizures, depression, obesity, and paradoxical reactions

• FLUOXETINE
• NEFAZODONE
• ERYTHROMYCIN
• RIFABUTIN
• KETOCONAZOLE
• MORPHINE
• CODEINE
• DIHYDROCODEINE
• BUPRENORPHINE

• Keeping a fixed time to go to bed and wake up consistently every day helps maintain a better sleeping and waking plan.

• Engage yourself in workouts, dancing, and walking that help promote calmness in the body so that you can enjoy a good night's sleep.

• Taking naps in a day can make it harder to fall asleep at night, so one should try to limit a nap to no more than half an hour and don't nap after 2 p.m. 

• Limit caffeine and alcohol consumption as it will not let you sleep and causes frequent urination.

• Avoid large, heavy meals before bed. One can have a light snack that helps to avoid heartburn.

• Avoid consumption of alcohol as it may increase drowsiness.

• Take less liquid before bedtime so that you won't have to urinate as often. One must keep their worries and planning aside and enjoy a warm bath or a massage before bedtime. It will help in having a good night's relaxing sleep.

• Do not take Stresnil 0.25 mg Tablet for a prolonged time as it may lead to mental or physical dependence on Stresnil 0.25 mg Tablet .

Insomnia: It is a sleep disorder that affects many people in the world. Persons dealing with insomnia don't feel energetic or refreshed after waking up from a long night's sleep. It is of two types: Acute and chronic insomnia. Acute insomnia may last from one night to a few weeks and occurs due to stress or life changes. Chronic insomnia may last from more than 3 nights per week to more than 3 months, making a person either wake up the whole night or have trouble falling asleep. Causes of insomnia include stress, physical pain, any traumatic event, psychological issues including depression, diabetes, side effects of certain medications, and many more. Signs and symptoms of insomnia include fatigue, irritability, trouble concentrating on tasks, and mood changes.