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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:18 PM IST
Starpress H 50 XL Tablet is used to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure. It contains Metoprolol and Hydrochlorothiazide, which work by relaxing the blood vessels. Thus, it helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. Also, it removes extra water/fluid and certain electrolyte overload from the body. Thereby, it lowers fluid overload, improves blood flow, lowers blood pressure and reduces the future risk of a heart attack and stroke. It may cause side effects such as nausea, fatigue, constipation, diarrhoea, headache, dizziness, increased blood uric acid, slow heart rate, decreased potassium level in the blood, altered blood lipid level, glucose intolerance, increased calcium level in the blood, and decreased magnesium level in blood.
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Synonym

S METOPROLOL+HYDROCHLOROTHIAZIDE

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Starpress H 50 XL Tablet

Starpress H 50 XL Tablet is used to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. Starpress H 50 XL Tablet is a combination medication generally used when a single medicine is unable to control high blood pressure. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.

Starpress H 50 XL Tablet is a combination of two medicines: Metoprolol and Hydrochlorothiazide. Metoprolol belongs to the class of drugs known as β-blockers that work by relaxing the blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Starpress H 50 XL Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke. This medicine needs to be taken regularly to be effective.

Take Starpress H 50 XL Tablet as prescribed by your doctor. Depending on your medical conditions, you are advised to take Starpress H 50 XL Tablet for as long as your doctor has prescribed it for you. You may experience nausea, fatigue, constipation, diarrhoea, headache, dizziness, increased blood uric acid, slow heart rate, decreased potassium level in the blood, altered blood lipid level, glucose intolerance, increased calcium level in the blood, and decreased magnesium level in blood. Most of these side effects of Starpress H 50 XL Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have had an allergic reaction to Starpress H 50 XL Tablet , have liver disease, kidney disease, asthma, heart failure, a heart valve problem, or have a history of a heart attack. Pregnant and breastfeeding women should consult their doctor before taking Starpress H 50 XL Tablet . Orthostatic hypotension (sudden lowering of blood pressure) might occur, so patients taking Starpress H 50 XL Tablet should get up with caution. A prolonged intake of Starpress H 50 XL Tablet may decrease your blood potassium levels. So, it is better to ask your doctor about foods high in potassium, like bananas or orange juice. Regular monitoring of blood pressure, kidney function, and electrolytes (sodium, potassium, calcium, etc.) is recommended while taking Starpress H 50 XL Tablet . Also, a healthy diet and regular exercise are necessary to keep blood pressure under control.

Uses of Starpress H 50 XL Tablet

Treatment of Hypertension (high blood pressure)

Medicinal Benefits

Starpress H 50 XL Tablet contains a combination of medicines: Metoprolol (beta-blockers) and Hydrochlorothiazide (thiazide diuretic or water pill). Metoprolol plays a vital role in relaxing our blood vessels by blocking the action of certain natural substances in our bodies. It helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Collectively, both help reduce blood pressure and the chance of a stroke, heart attack, and oedema (fluid overload).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Starpress H 50 XL Tablet

  • Nausea
  • Fatigue
  • Headache
  • Dizziness
  • Diarrhoea
  • Stuffy nose, sore throat
  • Slow heart rate
  • Increased blood uric acid
  • Decreased potassium/ magnesium level in the blood
  • Increased calcium level in the blood
  • Altered blood lipid level
  • Glucose intolerance

Drug Warnings

Don't stop taking Starpress H 50 XL Tablet without talking to your doctor first. Stopping Starpress H 50 XL Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Starpress H 50 XL Tablet if you have allergic to Starpress H 50 XL Tablet , have low blood pressure (less than 90 mm of Hg), very slow heartbeat, serious lung condition (like asthma), serious heart condition (sick sinus syndrome), or any heart blockage. Do not use Starpress H 50 XL Tablet if you are pregnant, planning for pregnancy, breastfeeding, or unable to urinate (anuria). It should not be given to the children as safety and effectiveness have not been established. Before taking Starpress H 50 XL Tablet you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), eye problem (glaucoma), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder like overactive thyroid (hyperthyroidism), adrenal gland cancer, or severe blood circulation problem (Raynaud’s syndrome). You should monitor your blood pressure regularly to make sure the Starpress H 50 XL Tablet is working efficiently. Besides this, prolonged intake of Starpress H 50 XL Tablet can lead to lowering of blood pressure (hypotension). So, daily monitoring of blood pressure is advisable.

Drug Interactions

Drug-Drug Interactions: Starpress H 50 XL Tablet may interact with other blood pressure-lowering pills or beta-blockers (acebutolol, atenolol, bisoprolol, carteolol, esmolol, nadolol,) other blood pressure-related medicines (lisinopril, enalapril, diltiazem, prazosin, terazosin, ramipril, atorvastatin), diuretics (furosemide, chlorothiazide, chlorthalidone, indapamide, metolazone), asthma medications (theophylline, aminophylline), pain killers (ibuprofen, aspirin), antifungals (terbinafine), anticancer (aldesleukin), blood thinner (dipyridamole), antibiotics (rifampicin), antivirals (ritonavir), antihistamines used to treat hay fever (diphenhydramine), medicines used to treat irregular heartbeat (amiodarone, propafenone, quinidine, disopyramide, procainamide, digoxin, lidocaine), anti-epilepsy medications (carbamazepine, phenobarbital), immune-suppressing drugs (cyclosporine).

Drug-Food Interactions: Starpress H 50 XL Tablet severely interacts with grapefruit and protein-enriched foods. Using Starpress H 50 XL Tablet with ayurvedic, homoeopathy, Unani, herbal supplements, or other OTC items may decrease the effects of Starpress H 50 XL Tablet . Hence, it is better to maintain at least 2 hours gap between the administration of Starpress H 50 XL Tablet and these products.

Drug-Disease Interactions: Starpress H 50 XL Tablet should not be given to people with diabetes, thyroid disease, asthma, cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure, gout, low serum potassium (hypokalemia), patients with nil urine output (anuria).

Drug-Drug Interactions Checker List

  • ACEBUTOLOL
  • ATENOLOL
  • BISOPROLOL
  • CARTEOLOL
  • ESMOLOL
  • NADOLOL
  • LISINOPRIL
  • ENALAPRIL
  • DILTIAZEM
  • PRAZOSIN
  • TERAZOSIN
  • RAMIPRIL
  • ATORVASTATIN
  • FUROSEMIDE
  • CHLOROTHIAZIDE
  • CHLORTHALIDONE
  • INDAPAMIDE
  • METOLAZONE
  • THEOPHYLLINE
  • AMINOPHYLLINE
  • IBUPROFEN
  • ASPIRIN
  • TERBINAFINE
  • ALDESLEUKIN
  • DIPYRIDAMOLE
  • RIFAMPICIN
  • RITONAVIR
  • DIPHENHYDRAMINE
  • AMIODARONE
  • PROPAFENONE
  • QUINIDINE
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • FLECAINIDE
  • DIGOXIN
  • LIDOCAINE
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE

Habit Forming

No

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.

  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.

  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.

  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.

  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.

  • Avoid the consumption of too much salt or salty food.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Regular physical activity or exercise like walking improves your blood flow.

  • When possible, elevate your legs or the swollen area on a chair or pillows.

  • Avoid standing or sitting for extended periods of time.

  • Avoid chronic stress as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force our heart uses to pump blood to all body parts. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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Alcohol

Caution

Drinking alcohol may increase tiredness, lower blood pressure causing dizziness or drowsiness. So avoid its intake with Starpress H 50 XL Tablet

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Pregnancy

Caution

Starpress H 50 XL Tablet is a pregnancy category C drug. It is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Small amounts of Starpress H 50 XL Tablet passes into the breast milk. However which is not enough to cause any problems to your baby. But, still, it is advisable to contact your doctor before breastfeeding your baby.

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Driving

Caution

You may experience dizziness, tiredness, or blurred vision while taking Starpress H 50 XL Tablet . So, it is not recommended to drive, use machinery, or perform other tasks.

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Liver

Caution

Starpress H 50 XL Tablet should be used with caution in patients with impaired hepatic function or progressive liver disease since minor alterations of fluid and electrolyte balance may precipitate hepatic coma. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Starpress H 50 XL Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

The safety and efficacy of Starpress H 50 XL Tablet in children have not been established. Starpress H 50 XL Tablet is not recommended in children.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - STA0079

Author Details

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FAQs

Starpress H 50 XL Tablet is used to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure.
Starpress H 50 XL Tablet contains a combination of drugs, namely; Metoprolol and Hydrochlorothiazide. Metoprolol is a beta-blocker that works specifically on the heart to reduce heart rate and make the heart more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic that lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.
Use of Starpress H 50 XL Tablet in diabetes may mask tachycardia (fast heart rate) occurring with low blood sugar level, but other symptoms like dizziness and sweating may not be significantly affected. So, if you are diabetic patients always consult a doctor before taking Starpress H 50 XL Tablet .
Your doctor may probably tell you to stop taking Starpress H 50 XL Tablet as it lowers blood pressure (hypotension) when combined with general anesthesia before surgery. So, please inform your doctor before surgery if you are taking Starpress H 50 XL Tablet .
No, Starpress H 50 XL Tablet is not recommended if you have frequent asthma attacks, severe asthma, or COPD (chronic obstructive pulmonary disease). Metoprolol in Starpress H 50 XL Tablet may cause wheezing (bronchospasm) and dyspnea. Thereby, it can make asthma worse. It is advised to consult your doctor before taking Starpress H 50 XL Tablet . You may need a dose adjustment and more frequent monitoring of your lung function to safely use both medications.
Starpress H 50 XL Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Starpress H 50 XL Tablet may lead to increased blood pressure with a high risk of heart attack and stroke in the future.
Yes, prolonged intake of Starpress H 50 XL Tablet may decrease your potassium levels in the bloodstream. So, it is better to ask your doctor about foods high in potassium like bananas or orange juice. Besides this, consult a doctor regarding the use of table salt or sodium chloride, or salt substitute containing potassium.
Hydrochlorothiazide in Starpress H 50 XL Tablet may make your more skin more sensitive to the sun and may also increase your risk for skin cancer if used for a long time. Try to limit your time in the sun and avoid tanning booths and sunlamps. You can also use sunscreen and wear protective clothing when outdoors.
Starpress H 50 XL Tablet can be taken with meals or immediately after meals. Swallow Starpress H 50 XL Tablet as a whole with water; do not crush or chew it.
The side effects of Starpress H 50 XL Tablet include nausea, fatigue, headache, dizziness, diarrhoea, stuffynose, sore throat, slow heart rate and glucose intolerance. Consult the doctor if any of these side effects persist or worsen.
Do not drink alcohol while taking Starpress H 50 XL Tablet as it might increase blood pressure-lowering effect of Starpress H 50 XL Tablet and cause drowsiness.
Starpress H 50 XL Tablet should be stored at room temperature and away from excess heat and moisture. Keep it out of sight and reach of children.
The serious side effects of Starpress H 50 XL Tablet include bronchospasm (constriction of air passages of the lung), slow heart rate, weak pulse, fainting, slow breathing , blurred vision, tunnel vision, eye pain, or seeing halos around lights, low potassium level, leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling(lacking in strength), or low sodium level headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady. Consult doctor if you experience any of these side effects.

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