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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Sizonorm Forte 25 Mg Tablet is used to treat schizophrenia or psychosis. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. In some cases, this medicine may cause side effects such as nausea, constipation, dryness in the mouth, weight gain, dizziness, and blurred vision. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Crescent Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Sizonorm Forte 25 Mg Tablet

Sizonorm Forte 25 Mg Tablet belongs to a group of medications called ‘antipsychotics’. It is used in the treatment of schizophrenia or psychosis. Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. Sizonorm Forte 25 Mg Tablet prevents the occurrence of these symptoms. 

Sizonorm Forte 25 Mg Tablet composed of three medications namely Chlorpromazine, Trifluoperazine,  and Trihexyphenidyl. Chlorpromazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic that works on the nervous system and corrects some of the side effects occurring during antipsychotic treatment. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Take Sizonorm Forte 25 Mg Tablet as prescribed by your doctor. You are advised to take Sizonorm Forte 25 Mg Tablet as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as nausea, constipation, sedation, dryness in the mouth, weight gain, orthostatic hypotension (sudden lowering of blood pressure on standing), urinary retention, the Increased prolactin level in blood, dizziness, blurred vision, nervousness. Most of these side effects of Sizonorm Forte 25 Mg Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take Sizonorm Forte 25 Mg Tablet if you are allergic to Sizonorm Forte 25 Mg Tablet or any other ingredients present in it. Before taking Sizonorm Forte 25 Mg Tablet, talk to your doctor if you or your family have a history of hypertension, CNS depression, narrow-angle glaucoma, neuroleptic malignant syndrome, tardive dyskinesia,  and have a history of dementia (memory loss). Sizonorm Forte 25 Mg Tablet is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Sizonorm Forte 25 Mg Tablet. Please do not stop taking Sizonorm Forte 25 Mg Tablet without your doctor’s advice as it may lead to withdrawal symptoms.
 

Uses of Sizonorm Forte 25 Mg Tablet

Treatment of Schizophrenia, Parkinsons disease.

Medicinal Benefits

Sizonorm Forte 25 Mg Tablet composed of three medications namely Chlorpromazine, Trifluoperazine,  and Trihexyphenidyl belongs to a group of medications called ‘antipsychotics’. It is used in the treatment of schizophrenia or psychosis. Chlorpromazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic that works on the nervous system and corrects some of the side effects occurring during antipsychotic treatment. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Directions for Use

Swallow it as a whole with a glass of water. Do not chew, crush or break it. Sizonorm Forte 25 Mg Tablet is to be taken with food.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sizonorm Forte 25 Mg Tablet

  • Nausea
  • Constipation
  • Sedation
  • Dryness in mouth
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Urinary retention
  • The increased prolactin level in the blood
  • Dizziness
  • Blurred vision
  • Nervousness

Drug Warnings

Do not take Sizonorm Forte 25 Mg Tablet if you are allergic to Sizonorm Forte 25 Mg Tablet or any other ingredients present in it. Before taking Sizonorm Forte 25 Mg Tablet, talk to your doctor if you or your family have a history of hypertension, CNS depression, narrow-angle glaucoma, neuroleptic malignant syndrome, tardive dyskinesia,  and have a history of dementia (memory loss). Sizonorm Forte 25 Mg Tablet is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Sizonorm Forte 25 Mg Tablet. Please do not stop taking Sizonorm Forte 25 Mg Tablet without your doctor’s advice as it may lead to withdrawal symptoms. Sizonorm Forte 25 Mg Tablet used with caution in kidney disease, liver disease and urinary obstruction.

Drug Interactions

Drug-drug interactions: Sizonorm Forte 25 Mg Tablet may interact with some medications, including antidepressants (citalopram, escitalopram, bupropion), medicines for Parkinson’s disease (levodopa, phenelzine), antiepileptic ( carbamazepine, phenobarbital), medicines control heartbeat ( amiodarone, disopyramide, quinidine), medicines used to calm emotion and mental disorder (olanzapine, prochlorperazine) antihypertensive (clonidine, guanethidine, propranolol), antibiotic (moxifloxacin) and medication used to treat mental illness (lithium), antihistamines (such as cetirizine, diphenhydramine), corticosteroids (prednisone).

Drug-food interactions: Sizonorm Forte 25 Mg Tablet may interact with grapefruit and alcohol and increase the risk of side-effects.

Drug-disease interactions: Sizonorm Forte 25 Mg Tablet should be used with caution in patients with heart problems such as QT prolongation (heart rhythm problem), acute alcohol abuse, central nervous system (CNS) depression, dementia, stroke, seizures, kidney diseases, diabetes, tardive dyskinesia, neuroleptic malignant syndrome, and liver problems.

Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • BUPROPION
  • PHENELZINE
  • LEVODOPA
  • CARBAMAZEPINE
  • PHENYTOIN
  • AMIODARONE
  • DISOPYRAMIDE
  • QUINIDINE
  • OLANZAPINE
  • PROCHLORPERAZINE
  • CLONIDINE
  • GUANETHIDINE
  • PROPRANOLOL
  • MOXIFLOXACIN
  • LITHIUM
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • PREDNISONE

Habit Forming

No

Diet & Lifestyle Advise

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. 
  • Exercise daily. Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.
  • You may also practice calming techniques such as meditation and deep breathing exercises.
  • Get some normal sleep. Having enough sleep will help to stabilize your mood.
  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.
  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.
  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting.
  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.
  • Eat cool foods instead of hot and spicy foods.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet and sports drinks for fluid make up which has got lost due to vomiting.

Special Advise

  • Do not stop Sizonorm Forte 25 Mg Tablet suddenly, because it may cause withdrawal symptoms. So please consult your doctor before taking Sizonorm Forte 25 Mg Tablet.

Disease/Condition Glossary

Schizophrenia (psychosis): It is a mental illness in which brain information processing is affected. Patients with schizophrenia develop symptoms such as hallucinations (see or hear unreal things), delusions (false beliefs) and become withdrawn from society. They lose the ability to differentiate reality from false beliefs. Schizophrenia and bipolar disorder may occur due to genetic factors, alcohol or drug abuse, mental trauma. Schizophrenia may also occur due to brain injuries or diseases.

Parkinson's disease: Parkinson's disease is a progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement.
 

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Alcohol

Caution

Alcohol may worsen the condition and increase the risk of side-effects while using Sizonorm Forte 25 Mg Tablet.

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Pregnancy

Caution

Sizonorm Forte 25 Mg Tablet is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

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Breast Feeding

Caution

Sizonorm Forte 25 Mg Tablet is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine

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Driving

Caution

Sizonorm Forte 25 Mg Tablet may cause especially to elderly patients, become drowsy, dizzy, light-headed, clumsy, unsteady or less alert than normal. If you are affected, do not drive or operate dangerous machinery after taking Sizonorm Forte 25 Mg Tablet.

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Liver

Caution

Sizonorm Forte 25 Mg Tablet is used with caution in liver diseases. Please consult your doctor before taking Sizonorm Forte 25 Mg Tablet.

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Kidney

Caution

Sizonorm Forte 25 Mg Tablet is used with caution in kidney diseases. Please consult your doctor before taking Sizonorm Forte 25 Mg Tablet.

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Children

Caution

Sizonorm Forte 25 Mg Tablet is not recommended for children below 1 year of age. However, please consult a doctor before giving Sizonorm Forte 25 Mg Tablet to children.

Country of origin

INDIA

Manufacturer/Marketer address

SCO-58, 59, Sector-17D Chandigarh-160017
Other Info - SIZ0021

Author Details

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FAQs

Sizonorm Forte 25 Mg Tablet is used in the treatment of schizophrenia or psychosis.
Sizonorm Forte 25 Mg Tablet composed of three medications namely Chlorpromazine, Trifluoperazine,  and Trihexyphenidyl belongs to a group of medications called ‘antipsychotics’. It is used in the treatment of schizophrenia or psychosis. Chlorpromazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic that works on the nervous system and corrects some of the side effects occurring during antipsychotic treatment. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.
Sizonorm Forte 25 Mg Tablet causes common side effects such as nausea, constipation, sedation, dryness in the mouth, weight gain, orthostatic hypotension (sudden lowering of blood pressure on standing), urinary retention, the Increased prolactin level in blood, dizziness, blurred vision, nervousness. Most of these side effects of Sizonorm Forte 25 Mg Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
Sizonorm Forte 25 Mg Tablet should be used with caution in hypertension, CNS depression, narrow-angle glaucoma, neuroleptic malignant syndrome, tardive dyskinesia,  and have a history of dementia (memory loss).
Sizonorm Forte 25 Mg Tablet cannot be stopped Sizonorm Forte 25 Mg Tablet suddenly, because Sizonorm Forte 25 Mg Tablet may cause withdrawal symptoms. So please consult your doctor before stopping Sizonorm Forte 25 Mg Tablet.
Sizonorm Forte 25 Mg Tablet is not recommended for use in patients with tardive dyskinesia which is an involuntary movement of the tongue, lips, and face unless the patient has concomitant Parkinson's disease due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

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