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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Sitacip Dm 100/10/1000 Tablet is an antidiabetic medicine used to treat Type II Diabetes adjunct to diet and exercise. It contains Dapagliflozin (which removes excess sugar from the body via urine), Sitagliptin (which works by increasing the amounts of certain natural substances that lower blood sugar when it is high) and Metformin (which works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines).

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Manufacturer/Marketer

Cipla Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Sitacip Dm 100/10/1000 Tablet

Sitacip Dm 100/10/1000 Tablet is an antidiabetic medicine used to treat diabetes. It is used for the treatment of Type II Diabetes. Type II Diabetes Mellitus is a serious condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels (either not creating enough insulin, or the insulin they do make does not accomplish its purpose in the body).

Sitacip Dm 100/10/1000 Tablet contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), which removes excess sugar from the body via urine, Sitagliptin (dipeptidyl peptidase-4 inhibitor), which works by increasing the amounts of certain natural substances that lower blood sugar when it is high and Metformin (biguanides), which works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Diet management and exercise, along with treatment of Sitacip Dm 100/10/1000 Tablet , are used to control blood sugar levels.

Sitacip Dm 100/10/1000 Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and allergic reactions. If these side effects persist or worsen, please consult your doctor. Sitacip Dm 100/10/1000 Tablet should be taken as prescribed by your doctor.

Sitacip Dm 100/10/1000 Tablet should be avoided if you are allergic to any of the medicines or the components in it. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Sitacip Dm 100/10/1000 Tablet . This can help prevent unwanted effects. Let your doctor know if you are pregnant or breastfeeding before taking Sitacip Dm 100/10/1000 Tablet . It is not recommended for use in children below 18 years of age.

Uses of Sitacip Dm 100/10/1000 Tablet

Treatment of Type II Diabetes Mellitus

Medicinal Benefits

Sitacip Dm 100/10/1000 Tablet  is a combination of three drugs: Sitagliptin, Dapagliflozin and Metformin. Sitacip Dm 100/10/1000 Tablet belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus adjunct to diet and exercise. It removes excess sugar from the body via urine, increases the amounts of certain natural substances that lower blood sugar when it is high, reduces sugar production by cells in the liver and delays sugar absorption from the intestines.

Directions for Use

Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sitacip Dm 100/10/1000 Tablet

  • Headache
  • Nausea
  • Stomach upset
  • Vomiting
  • Abdominal pain

Drug Warnings

Sitacip Dm 100/10/1000 Tablet should be avoided if you are allergic to any of the medicines or the components in it. Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements. This can help prevent unwanted effects. Sitacip Dm 100/10/1000 Tablet is not recommended for use in patients with severe liver or kidney disease. It is unknown whether Sitacip Dm 100/10/1000 Tablet can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age. Avoid drinking alcohol while on Sitacip Dm 100/10/1000 Tablet  as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).

Drug Interactions

Drug-Drug Interactions: Sitacip Dm 100/10/1000 Tablet interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine).

Drug-Food Interactions: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with Sitacip Dm 100/10/1000 Tablet .

Drug-Disease Interactions: Inform your doctor if you have any kidney or liver disease or heart problems.

Drug-Drug Interactions Checker List

  • CEPHALEXIN
  • CIMETIDINE
  • DIGOXIN
  • LAMOTRIGINE
  • BUPROPION
  • CIPROFLOXACIN
  • TOPIRAMATE
  • RANOLAZINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
  • Include whole-grain foods, fruits and veggies, and other fibre-enriched foods.
  • Add omega-3 fatty acid-containing oils for daily cooking.
  • Avoid too much stress, as it may elevate your blood sugar level. To control stress-related blood sugar changes, you can adopt stress management techniques like mindfulness, meditation, or yoga.
  • Weight loss gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Avoid smoking and alcohol consumption while on treatment with Sitacip Dm 100/10/1000 Tablet .
  • Take short, frequent meals, and avoid prolonged fasting when taking Sitacip Dm 100/10/1000 Tablet .

Special Advise

  • Sitacip Dm 100/10/1000 Tablet may sometimes cause hypoglycemia (low blood sugar levels) as a side effect. Try to carry candies or sugar biscuits in your pocket every time you feel symptoms such as sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc.
  • Lifestyle modifications are the most important step in controlling blood sugar levels.
  • Your doctor may advise frequent blood tests to check your blood sugar levels.

Disease/Condition Glossary

Type II Diabetes Mellitus: It is a chronic and lifelong condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels. Therefore, people affected with type 2 diabetes either do not produce enough insulin or there is resistance to the action of insulin. Individuals middle-aged or older are most likely to suffer from type 2 diabetes, which is also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, weight gain, and blurred vision. 

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Alcohol

Unsafe

Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Sitacip Dm 100/10/1000 Tablet .

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Pregnancy

Consult your doctor

There are no adequate studies on the effect of Sitacip Dm 100/10/1000 Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Sitacip Dm 100/10/1000 Tablet .

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Breast Feeding

Caution

Sitacip Dm 100/10/1000 Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Sitacip Dm 100/10/1000 Tablet .

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Driving

Safe

Sitacip Dm 100/10/1000 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Sitacip Dm 100/10/1000 Tablet with caution, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Renal impairment also increases the risk of lactic acidosis. Hence, Sitacip Dm 100/10/1000 Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Sitacip Dm 100/10/1000 Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - SIT0422

FAQs

Sitacip Dm 100/10/1000 Tablet is used to treat type II diabetes mellitus, a condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels.
Sitacip Dm 100/10/1000 Tablet is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.
If you forget to take Sitacip Dm 100/10/1000 Tablet , take it as soon as you remember. However, if it's time for the next dose, avoid taking it and do not double dose to make up the missed dose. Taking an overdose might cause your sugar level to fall down rapidly.

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