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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:26 PM IST
Silhexa Cream is used to treat burns and prevent skin infections. It contains Silver sulfadiazine and Chlorhexidine, which inhibit the production of folic acid (a vitamin) necessary for bacteria to multiply and increase in numbers. Thereby, destroys bacteria. Also, it works by binding to the skin strongly and kills micro-organisms on the skin and prevents infection. In some cases, you may experience irritation, itching, or burning sensation at the site of application.
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Synonym

SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE

Consume Type

TOPICAL

Return Policy

Not Returnable

About Silhexa Cream

Silhexa Cream belongs to a combination of medicines called 'topical antibiotics' primarily used to treat burns and prevent skin infections. Burns are common household injuries that damage the skin or deeper tissues and cause the death of affected skin cells. Based on the severity of skin damage, burns are categorized into 3 main types: first-degree, second-degree, and third-degree burns. 

Silhexa Cream is a combination of two drugs:  Silver sulfadiazine (antibiotic) and Chlorhexidine (antiseptic). Silver sulfadiazine belongs to the class of sulfa antibiotics that inhibit the production of folic acid (a vitamin) necessary for bacteria to multiply and increase in numbers. Thereby, destroys bacteria. Chlorhexidine belongs to the antiseptics class that works by binding to the skin strongly and kills micro-organisms on the skin and prevents infection.

Use Silhexa Cream as prescribed. Silhexa Cream is for external use only. Avoid contact of Silhexa Cream with nose, ears, mouth, or eyes. In case Silhexa Cream comes in contact with these areas accidentally, rinse with water thoroughly. Your doctor will advise you how often you take Silhexa Cream based on your medical condition. In some cases, you may experience irritation, itching, or burning sensation at the site of application. Most of these side effects of Silhexa Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Silhexa Cream or any other medicines, please tell your doctor. Do not swallow Silhexa Cream. In case of accidental swallowing, contact a nearby poison control center or consult a doctor immediately. If you are pregnant or a nursing mother, please inform your doctor before taking Silhexa Cream. Wear sterile disposable gloves if you apply Silhexa Cream for others and keep the treated area clean to prevent further infection. You are advised to cover the burn wounds with Silhexa Cream all the time and cover the treated area with dressings or bandages if advised by your doctor. Do not apply Silhexa Cream in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. Avoid contact of Silhexa Cream with clothes or fabric as it may cause staining.  If you have glucose-6-phosphate dehydrogenase (a genetic enzyme) deficiency, kidney or liver problems, inform your doctor before taking Silhexa Cream. 

Uses of Silhexa Cream

Treatment of Burns

Medicinal Benefits

Silhexa Cream is a combination of two drugs, namely:  Silver sulfadiazine and Chlorhexidine. Silver sulfadiazine belongs to the class of sulfa antibiotics that works by inhibiting the production of folic acid (a vitamin) that is necessary for bacteria to multiply and increase in numbers. Thereby, destroys bacteria. Chlorhexidine belongs to the class of antiseptics that works by binding to the skin strongly and kills micro-organisms on the skin and prevents infection. Also, Chlorhexidine is used to disinfect the hands before performing surgery to prevent the entry of germs into the body when the skin is cut. It kills a wide range of yeasts, bacteria, and some viruses and fungi.  

Directions for Use

Use Silhexa Cream as prescribed by your doctor. Apply a small amount of Silhexa Cream on the clean and dry affected area with the help of an applicator or a clean cotton ball or swab. Silhexa Cream is only for external use. Avoid contact of Silhexa Cream with nose, mouth or eyes. In case Silhexa Cream comes in contact with these areas accidentally, rinse with water thoroughly. Wash your hands before and after using Silhexa Cream if your hands are not the affected area to prevent the spread of infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Silhexa Cream

  • Irritation, itching or burning sensation at the site of application

Drug Warnings

If you are allergic to Silhexa Cream or any other medicines, please tell your doctor. Silhexa Cream is for external use only. Avoid contact of Silhexa Cream with nose, ears, mouth, or eyes. In case Silhexa Cream comes in contact with these areas accidentally, rinse with water thoroughly. Wear sterile disposable gloves if you are applying Silhexa Cream for others and keep the treated area clean to prevent further infection. You are advised to cover the burn wounds with Silhexa Cream all the time and cover the treated area with dressings or bandages if advised by your doctor. If you are pregnant or a nursing mother, please inform your doctor before taking Silhexa Cream. Do not apply Silhexa Cream in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. Avoid contact of Silhexa Cream with clothes or fabric as it may cause staining.  Do not swallow Silhexa Cream. In case of accidental swallowing, contact a nearby poison control center or consult a doctor immediately. If you have glucose-6-phosphate dehydrogenase (a genetic enzyme) deficiency, or kidney or liver problems, inform your doctor before taking Silhexa Cream.

Drug Interactions

Drug-Drug Interaction: No interactions found.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have glucose-6-phosphate dehydrogenase (a genetic enzyme) deficiency, kidney or liver problems, inform your doctor before taking Silhexa Cream.

Habit Forming

No

Diet & Lifestyle Advise

  • Include protein-rich foods such as yogurt, chicken, and eggs in your diet as there is a loss of protein through burn wounds and breakdown of muscles to produce extra energy for the healing process. The additional protein is required to rebuild lost muscle.
  • Add more carbohydrates to your diets such as potatoes, beans, and rice as glucose in carbohydrates is essential for healing.
  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Drink plenty of water to stay hydrated and avoid drinking sugary beverages.

Special Advise

  • Regular blood tests are recommended while using Silhexa Cream to monitor kidney functioning.
  • Please consult a dermatologist if your skin condition persists for more than 1 month.

Disease/Condition Glossary

Burns are common household injuries that damage the skin or deeper tissues and cause the death of affected skin cells. Based on the severity of skin damage, burns are categorized into 3 main types namely, first-degree (also known as superficial burns which cause minimal damage to the skin), second-degree (extends beyond the top layer of skin and causes blisters), and third-degree burns (most severe burns extending through every layer of skin).  Burns may be caused due to excessive sun exposure, electrical burns, chemical burns, hot, boiling liquids, fires including flames from candles, matches, or lighters.

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Alcohol

Caution

The interaction of Silhexa Cream with alcohol is unknown. Please consult a doctor before consuming alcohol while using Silhexa Cream.

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Pregnancy

Unsafe

Silhexa Cream is a category B pregnancy drug and is usually not recommended for pregnant women as it may cause adverse effects in the new-born. However, please consult a doctor if you are pregnant before using Silhexa Cream.

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Breast Feeding

Caution

Silhexa Cream may be excreted in human milk and cause harm to the baby. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Silhexa Cream usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Silhexa Cream in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Silhexa Cream in patients with kidney problems, please consult a doctor.

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Children

Caution

Silhexa Cream is not recommended for babies below 2 months of age as it may cause severe irritation. However, Silhexa Cream should be used with caution in children above 2 months if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

70-A Pocket Ap Pitampura,Delhi-34
Other Info - SI56166

Author Details

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FAQs

Silhexa Cream is used to treat burns and prevent skin infections.
Silhexa Cream contains Silver sulfadiazine and Chlorhexidine. Silver sulfadiazine is an antibiotic that works by inhibiting the production of folic acid (a vitamin) that is necessary for bacteria to multiply and increase in numbers. Thereby, destroys bacteria. Chlorhexidine is an antiseptic that works by binding to the skin strongly and kills micro-organisms on the skin. Together, Silhexa Cream helps to clean the skin and prevent infection.
Yes, Silhexa Cream may cause itching of the skin at the site of application as a temporary side effect. However, if the itching persists or worsens, please consult a doctor.
You are not recommended to use Silhexa Cream with prilocaine (local anaesthetic) as it may increase the risk of methemoglobinemia (a blood disorder in which very less oxygen is delivered to vital organs and tissues). If you experience shortness of breath, dizziness, rapid heartbeat, anxiety, light-headedness, grey discolouration of the skin, nail bed or mouth, confusion, headache, nausea or tiredness, please consult a doctor immediately. However, consult your doctor before using Silhexa Cream with other medicines.
Silhexa Cream may cause staining of clothes as it contains Chlorhexidine responsible for staining. Therefore, avoid contact of Silhexa Cream with clothes or fabric and also avoid bleach to wash fabric that is in contact with Silhexa Cream as it may cause a permanent stain.
You are recommended to use Silhexa Cream for as long as your doctor has prescribed it. However, if the condition persists or worsens after using Silhexa Cream for 1 week, please consult a doctor.
No, please do not stop using Silhexa Cream without consulting your doctor even if you find symptomatic relief as discontinuing suddenly may worsen the infection. Therefore, complete the full course of Silhexa Cream as your doctor has prescribed it, and if you experience any difficulty while using Silhexa Cream, please consult your doctor.
Silhexa Cream typically starts working soon after application, but it may take few days for your symptoms to improve significantly. It is important to use Silhexa Cream regularly and complete the full course of treatment as prescribed by your doctor to ensure the best results.
The common side effects of Silhexa Cream are irritation, itching, or burning sensation at the site of application. If any of these side effects persist or worsen, please consult your doctor.

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