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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:37 PM IST
Serset-50 Tablet is used in the treatment of depression, post-traumatic stress disorder (PTSD), social anxiety disorder, panic disorder and obsessive-compulsive disorder (OCD). It contains Sertraline, which increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic. Some people may experience side effects such as drowsiness, dizziness, insomnia (difficulty in sleeping), dry mouth, nausea, headache, diarrhoea, tiredness or ejaculation failure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

SERTRALINE-50MG

Manufacturer/Marketer

Recoupe Pharma

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-26

for this medicine

About Serset-50 Tablet

Serset-50 Tablet belongs to a class of antidepressant drugs called selective serotonin reuptake inhibitors (SSRIs) used in the treatment of depression, post-traumatic stress disorder (PTSD), social anxiety disorder, panic disorder and obsessive-compulsive disorder (OCD). Depression is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do. OCD is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions), leading to repetitive behaviours (compulsions). Panic disorder is linked to anxiety with sudden feelings of fear when there is no danger in reality. PTSD is a mental condition that occurs after experiencing a very emotional or terrifying event and has symptoms similar to anxiety and depression. Social anxiety disorder (social phobia) is associated with intense anxiety or distress in social situations.

Serset-50 Tablet contains Sertraline that works by inhibiting the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Serset-50 Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Take Serset-50 Tablet with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not break, crush or chew it. Your doctor will advise you how often you take Serset-50 Tablet based on your medical condition. Some people may experience drowsiness, dizziness, insomnia (difficulty in sleeping), dry mouth, nausea, headache, diarrhoea, tiredness or ejaculation failure. Most of these side effects of Serset-50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Serset-50 Tablet or any other medicines, please tell your doctor. Serset-50 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years and not treat any other conditions in children below 18 years of age. Serset-50 Tablet is not recommended for use during pregnancy, especially in the last 3 months. It may cause a serious condition in the baby, such as persistent pulmonary hypertension of the newborn (PPHN), which causes the baby to appear bluish and breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy. Serset-50 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Serset-50 Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Serset-50 Tablet , inform your doctor as they may worsen in the initial days of taking Serset-50 Tablet . Do not take Serset-50 Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide and methylene blue to treat depression and opioids as it may cause severe adverse effects.

Uses of Serset-50 Tablet

Treatment of Depression, Post-traumatic stress disorder (PTSD), Social anxiety disorder, Panic disorder, Obsessive-compulsive disorder (OCD).

Medicinal Benefits

Serset-50 Tablet contains Sertraline, an antidepressant that inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Serset-50 Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Serset-50 Tablet

  • Drowsiness

  • Dizziness
  • Insomnia (sleeplessness)
  • Dry mouth
  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Ejaculation failure

Drug Warnings

If you are allergic to Serset-50 Tablet or any other medicines, please tell your doctor. Serset-50 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years and does not treat any other conditions in children below 18 years of age. Serset-50 Tablet is not recommended for use during pregnancy, especially in the last 3 months. It may cause a serious condition in the baby, such as persistent pulmonary hypertension of the newborn (PPHN), which causes the baby to appear bluish and breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy. Serset-50 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Serset-50 Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Serset-50 Tablet , inform your doctor as they may worsen in the initial days of taking Serset-50 Tablet . Do not take Serset-50 Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide and methylene blue to treat depression and opioids pain killer as it may cause severe adverse effects. If you have diabetes, fits, bipolar disorder, bleeding disorders, glaucoma, severe diarrhoea, low sodium or potassium levels in the blood, neuroleptic malignant syndrome or serotonin syndrome (potentially life-threatening conditions), liver or heart problems, inform your doctor before taking Serset-50 Tablet . 

Drug Interactions

Drug-Drug Interactions: Serset-50 Tablet may have interaction with antiparkinson drug (selegiline), antibiotic (linezolid), antipsychotic drugs (pimozide, haloperidol, perphenazine, olanzapine, levomepromazine), opioid pain killers (buprenorphine, fentanyl, tramadol), opioid antagonists (naloxone), blood thinners (warfarin, ticlopidine), monoamine oxidase inhibitors used to treat depression (moclobemide, methylene blue), antifungals (fluconazole, posaconazole, voriconazole, ketoconazole, itraconazole), antibiotics (erythromycin, telithromycin, clarithromycin, levofloxacin), antidepressants (nefazodone, fluoxetine, fluvoxamine, amitriptyline, nortriptyline, desipramine), antimanic drug (lithium), anticonvulsants  (phenytoin, carbamazepine, phenobarbital), painkillers (ibuprofen, aspirin), antidiabetic drug (tolbutamide), antacids (cimetidine, pantoprazole, rabeprazole, omeprazole, lansoprazole).

Drug-Food Interactions: Serset-50 Tablet may interact with St. John’s wort (a herbal medicine used to treat depression) and grapefruit juice as they may increase the risk of a build-up of high levels of serotonin in the body. Also, avoid intake of alcohol while taking Serset-50 Tablet as it may increase side effects such as drowsiness, dizziness or difficulty in concentrating.

Drug-Disease Interactions: If you have diabetes, fits, bipolar disorder, bleeding disorders, glaucoma, severe diarrhoea, low sodium or potassium levels in the blood, neuroleptic malignant syndrome or serotonin syndrome (potentially life-threatening conditions), liver or heart problems, inform your doctor before taking Serset-50 Tablet .

Drug-Drug Interactions Checker List

  • SELEGILINE
  • LINEZOLID
  • PIMOZIDE
  • HALOPERIDOL
  • PERPHENAZINE
  • OLANZAPINE
  • BUPRENORPHINE
  • FENTANYL
  • TRAMADOL
  • NALOXONE
  • WARFARIN
  • TICLOPIDINE
  • MOCLOBEMIDE
  • METHYLENE BLUE
  • FLUCONAZOLE
  • POSACONAZOLE
  • VORICONAZOLE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • CLARITHROMYCIN
  • LEVOFLOXACIN
  • NEFAZODONE
  • FLUOXETINE
  • FLUVOXAMINE
  • AMITRIPTYLINE
  • NORTRIPTYLINE
  • DESIPRAMINE
  • LITHIUM
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • IBUPROFEN
  • ASPIRIN
  • TOLBUTAMIDE
  • CIMETIDINE
  • PANTOPRAZOLE
  • RABEPRAZOLE
  • OMEPRAZOLE
  • LANSOPRAZOLE
  • LEVOMEPROMAZINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables and whole grains. Avoid fried foods, high-fat dairy products, pastries and processed foods as they may worsen anxiety. Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters.

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Regularly attend therapy sessions.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Avoid smoking and alcohol consumption.

Special Advise

  • Serset-50 Tablet may interfere with a urine test. Therefore, it is advised to inform your doctor or lab technician that you are taking Serset-50 Tablet .

Disease/Condition Glossary

Depression: It is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drugs use, and medical conditions.

Obsessive-compulsive disorder (OCD): It is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions) leading to repetitive behaviours (compulsions).

Panic disorder: It is linked to anxiety with sudden fear even when there is no danger in reality.

Post-traumatic stress disorder (PTSD): It is a mental condition that occurs after experiencing a very emotional or terrifying event and has symptoms similar to anxiety and depression.

Social anxiety disorder: It is social phobia associated with intense anxiety or distress in social situations.

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Alcohol

Unsafe

Avoid consumption of alcohol with Serset-50 Tablet as it may increase the risk of drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Serset-50 Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy especially in the last 3 months as it may cause a serious condition in the baby such as persistent pulmonary hypertension of the newborn (PPHN) which causes the baby to appear bluish and makes breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Serset-50 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Serset-50 Tablet is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Unsafe

Serset-50 Tablet may cause dizziness, drowsiness or impair thinking. Therefore, avoid driving if you experience any of these symptoms after taking Serset-50 Tablet .

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Liver

Caution

Take Serset-50 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

If you have any concerns regarding the use of Serset-50 Tablet in patients with kidney problems, please consult a doctor.

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Children

Caution

Serset-50 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years. Serset-50 Tablet is not recommended to treat any other disorders in children below 18 years of age.

Country of origin

India

Manufacturer/Marketer address

30, Geetanjli Society, Near Kameshwar School, Jodhpur, Cross Road, Satellite,, Ahmedabad - 380015, Gujarat, India
Other Info - SER0677

Author Details

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FAQs

Serset-50 Tablet used in the treatment of Depression, Post-traumatic stress disorder (PTSD), Social anxiety disorder, Panic disorder, and Obsessive-compulsive disorder (OCD).
Yes, Serset-50 Tablet may be used to treat a panic disorder by reducing fear. However, please consult a doctor before using the Serset-50 Tablet .
No, you are not recommended to take Serset-50 Tablet with opioids as co-administration of these medicines may cause adverse effects such as hallucinations, increased muscle tension, excessive sweating, fever, anxiety, involuntary, rhythmic contractions of muscles, including the muscles that control eye movement, tremor or even coma. However, before using Serset-50 Tablet with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.
Yes, Serset-50 Tablet may cause self-harming or suicidal thoughts, especially in patients aged less than 25 years or who have a history of self-harming thoughts. Therefore, please consult a doctor immediately if you experience any such thoughts while taking Serset-50 Tablet .
It takes about 2 weeks or longer, usually for Serset-50 Tablet to work. However, it is recommended to use Serset-50 Tablet for as long as your doctor has prescribed it for you.
Serset-50 Tablet may affect male fertility as it may reduce sperm quality. Therefore, please consult a doctor if you are planning to father a child.
Serset-50 Tablet should be used with caution in diabetic patients as it may alter blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Serset-50 Tablet , especially if you have diabetes, and the dose of diabetic medicines may be adjusted appropriately by your doctor.
Serset-50 Tablet contains Sertraline, which inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases the serotonin (chemical messenger) activity in the brain that regulates mood, behaviour and emotions. Thereby, Serset-50 Tablet helps in relieving depression, lightening the mood and relieving anxiety symptoms such as fear and panic.
The side effects of Serset-50 Tablet include nausea, headache, diarrhoea, tiredness, drowsiness, dizziness and insomnia (difficulty sleeping). If these side effects persist or worsen, please consult your doctor.
You are recommended to take Serset-50 Tablet for as long as it is prescribed by your doctor, which may be for several months. Do not stop taking Serset-50 Tablet before the advised time as it may cause depression to recur.
Take Serset-50 Tablet as advised by your doctor. It can be taken with or without food at any time of the day and is usually taken once a day. Take it as per your convenience but preferably at the same time every day. Some people should take it in the morning who have sleep difficulty after taking Serset-50 Tablet . Whereas, some take it at night to minimize the side effects of vomiting and nausea.
Yes, sleepiness is a common side effect of Serset-50 Tablet . Avoid driving or using heavy machinery if you feel sleepy, dizzy, or tired after taking Serset-50 Tablet . This usually occurs within the first few days and weeks after starting Serset-50 Tablet , which may disappear after 2-3 months.
Serset-50 Tablet increases the serotonin levels which is an important chemical and a neurotransmitter. This helps to improve and regulate mood, resulting in an improvement in the anxiety symptoms.
No, do not stop taking Serset-50 Tablet without consulting your doctor as discontinuing suddenly may cause withdrawal symptoms. Therefore, it is important to reduce the dose gradually with time (over several weeks or months).
The withdrawal symptoms of Serset-50 Tablet include numbness or tingling in the hands or feet, dizziness, nausea, trouble sleeping, headaches, feeling agitated or anxious, and shaking. However, these symptoms are usually mild to moderate and disappear 1-2 weeks after stopping Serset-50 Tablet .
The symptoms of Serset-50 Tablet overdose include fever, nausea, vomiting, dizziness, confusion, shakiness, and a rapid heartbeat. Whereas, serious side effects include heart problems, fainting, delirium, and changes in blood pressure. If you experience such symptoms, contact your doctor immediately.

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