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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Selepeg 600 Tablet 10's is used to treat pulmonary arterial hypertension (high blood pressure in the lungs), slow down the worsening of symptoms, and reduce the chance of hospitalisation. It contains Selexipag, which works by widening the pulmonary arteries and reducing their hardening. This makes it easier for the heart to pump blood through the pulmonary arteries, lowering the pressure in them.

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Composition

SELEXIPAG-600MCG

Manufacturer/Marketer

Msn Laboratories Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Selepeg 600 Tablet 10's

Selepeg 600 Tablet 10's belongs to the group of medicines called selective non-prostanoid IP prostacyclin receptor agonists used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to slow down the worsening of symptoms and to reduce the chance of hospitalisation.

Selepeg 600 Tablet 10's contains Selexipag, which works by widening the pulmonary arteries and reducing their hardening. This makes it easier for the heart to pump blood through the pulmonary arteries. Thereby, it lowers the pressure in the pulmonary arteries.

In some cases, Selepeg 600 Tablet 10's may cause side effects such as headache, nausea, vomiting, diarrhoea, and stuffy nose. Most of these side effects may not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.

Do not take Selepeg 600 Tablet 10's if you are pregnant or breastfeeding. Selepeg 600 Tablet 10's is not recommended for use in children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Selepeg 600 Tablet 10's

Treatment of Pulmonary arterial hypertension (PAH)

Medicinal Benefits

Selepeg 600 Tablet 10's belongs to the group of medicines called selective non-prostanoid IP prostacyclin receptor agonists used to treat pulmonary arterial hypertension (high blood pressure in the lungs), delay disease progression and lower the risk of hospitalisation for pulmonary arterial hypertension. Selepeg 600 Tablet 10's contains Selexipag, which works by widening the pulmonary arteries and reducing their hardening. This makes it easier for the heart to pump blood through the pulmonary arteries. Thereby, Selepeg 600 Tablet 10's lowers the pressure in the pulmonary arteries, relieves symptoms of pulmonary arterial hypertension and slows down its progression.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Selepeg 600 Tablet 10's

  • Headache
  • Flushing (reddening of the face)
  • Nausea
  • Vomiting
  • Diarrhoea
  • Nasopharyngitis (stuffed nose)
  • Jaw pain, joint pain, muscle pain, leg pain

Drug Warnings

Do not take Selepeg 600 Tablet 10's if you are allergic to any of its components, if you have/had heart problems such as unstable angina, severe coronary heart disease, heart attack within last six months, weak heart, severe irregular heartbeat, defect of heart valves, or if you had a stroke within the last three months, reduced blood supply to the brain, or if you are taking gemfibrozil. Inform the doctor if you have low blood pressure associated with dizziness, severe diarrhoea or vomiting, thyroid problems, severe kidney problems, undergoing dialysis, severe liver problems, or if you are taking medicines for high blood pressure. Do not take Selepeg 600 Tablet 10's if you are pregnant or breastfeeding. Selepeg 600 Tablet 10's is not recommended for children. Let the doctor know if you are taking any other medicines, including supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking fibrates (gemfibrozil), antiplatelet (clopidogrel), iron chelators (deferasirox), immunomodulatory agent (teriflunomide), anticonvulsant (carbamazepine, phenytoin, valproic acid), anti-gout (probenecid), or antibiotic (fluconazole).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have unstable angina, severe coronary heart disease, heart attack, weak heart, severe irregular heartbeat, defect of heart valves, stroke, or reduced blood supply to the brain.

Drug-Drug Interactions Checker List

  • GEMFIBROZIL
  • CLOPIDOGREL
  • DEFERASIROX
  • TERIFLUNOMIDE
  • CARBAMAZEPINE
  • PHENYTOIN
  • VALPROIC ACID
  • PROBENECID
  • FLUCONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Lower your intake of salt. This helps in reducing the risk of developing oedema.
  • Include vegetables, fruits, whole grains, lean meats, poultry, fish, and fat-free/low-fat dairy products in your diet.
  • Avoid canned foods, processed foods, pickled, and frozen foods. Instead, consume fresh foods.
  • Limit consumption of caffeine and alcohol as they can alter blood pressure.
  • Monitor fluid intake to prevent swelling/fluid retention.

Special Advise

  • Women of childbearing potential must use effective contraceptives while on treatment with Selepeg 600 Tablet 10's.

Disease/Condition Glossary

Pulmonary arterial hypertension (PAH): PAH is high blood pressure in the blood vessels that carry blood from the heart to the lungs (pulmonary artery). It occurs due to narrowed or blocked blood vessels, which increases the workload on the heart. Symptoms include tiredness, dizziness, shortness of breath, chest pain, and swelling in the legs and ankles.

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Alcohol

Consult your doctor

It is not known whether Selepeg 600 Tablet 10's interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Selepeg 600 Tablet 10's is not recommended during pregnancy. Consult the doctor if you become pregnant during treatment with Selepeg 600 Tablet 10's.

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Breast Feeding

Unsafe

It is not known if Selexipag passes into breast milk. Selepeg 600 Tablet 10's is not recommended during lactation.

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Driving

Caution

Selepeg 600 Tablet 10's may cause headaches and low blood pressure, affecting your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Selepeg 600 Tablet 10's is not recommended for patients with severe liver impairment. Dose adjustment may be needed in people with moderate hepatic impairment. Consult the doctor if you have liver problems.

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Kidney

Caution

Please consult the doctor if you have any concerns regarding the usage of Selepeg 600 Tablet 10's in patients with kidney impairment.

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Children

Unsafe

Selepeg 600 Tablet 10's is not recommended for use in children below 18 years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Msn Laboratories Pvt.Ltd., Msn House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, India
Other Info - SEL0179

Author Details

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FAQs

Selepeg 600 Tablet 10's is used to treat Pulmonary arterial hypertension (PAH).
Selepeg 600 Tablet 10's relaxes the blood vessels in the lungs and allows the blood to flow easily. Thereby, it relieves the symptoms of pulmonary arterial hypertension and slows down its progression.
Do not stop taking Selepeg 600 Tablet 10's on your own. Selepeg 600 Tablet 10's helps control the symptoms of PAH but does not cure it. Therefore, continue taking Selepeg 600 Tablet 10's for as long as it has been prescribed by the doctor.
Selepeg 600 Tablet 10's should be used with caution in patients older than 75 years as there is limited experience in this age group. Consult the doctor if you have any concerns.
Let the doctor know if you are taking gemfibrozil, a medicine used to lower fat levels in the blood. If you are taking gemfibrozil, your doctor may tell you not to take Selepeg 600 Tablet 10's.

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