Scapho 150Mg/Ml Inj belongs to the class of monoclonal antibodies. It is primarily indicated for the treatment of moderate to severe plaque psoriasis in patients six years and older who are candidates for systemic therapy or phototherapy, active psoriatic arthritis (PsA) in patients two years and older; adults with active ankylosing spondylitis (AS), adults with active non-radiographic axial spondyloarthritis (nr-axSpA).

Scapho 150Mg/Ml Inj consists of Secukinumab. It works by inhibiting the release of inflammatory cytokines and chemokines that contribute to autoimmune and inflammatory diseases.

Scapho 150Mg/Ml Inj is a parenteral medicine. A trained healthcare professional will administer it. Hence, do not self-administer. Scapho 150Mg/Ml Inj may cause side effects such as mild nose and throat infection, diarrhoea, upper respiratory tract infection, and injection site reactions. These side effects do not require medical attention or resolve over time.

Before taking Scapho 150Mg/Ml Inj, inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Also, tell your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Secukinumab is not recommended if you are pregnant. If you become pregnant while taking secukinumab, notify your healthcare professional immediately. Breastfeeding mothers should inform the physician whether to stop or nurse the child while on treatment.

Scapho 150Mg/Ml Inj consists of Secukinumab, which belongs to the class of monoclonal antibodies. Scapho 150Mg/Ml Inj binds to the interleukin-17A cytokine and inhibits the interaction with the IL-17 receptor. In simple terms, it inhibits the release of inflammatory cytokines and chemokines that contribute to autoimmune and inflammatory diseases. This helps reduce inflammation and pain, redness, and inflammation (swelling) caused by various autoimmune diseases.

• Cold symptoms (mild infection of the nose and throat)
• Diarrhea
• Upper respiratory tract infection
• Injection site reactions
• Difficulty breathing

Before taking Scapho 150Mg/Ml Inj, inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Also, tell your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Scapho 150Mg/Ml Inj is not recommended in populations with serious infections, hypersensitivity reactions, Tuberculosis (TB), inflammatory bowel disease, and Eczematous Eruptions (skin reactions). So, inform your healthcare professional about all your medical conditions and any allergic reactions to food or medications. Do not take any vaccinations, especially live while on therapy with this medicine. Scapho 150Mg/Ml Inj is not recommended if you are pregnant. If you become pregnant while taking secukinumab, notify your healthcare professional immediately. A breastfeeding mother should inform the physician whether to stop or nurse the child while on treatment.

Drug-Drug Interactions: Scapho 150Mg/Ml Inj may interact with other immunosuppressants (e.g. adalimumab, certolizumab), immunomodulating medication (e.g. fingolimod), antirheumatic drug (e.g. leflunomide), and vaccines (e.g. BCG vaccine, dengue vaccine)

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Scapho 150Mg/Ml Inj interacts with disease conditions, including infections (bacterial/fungal/protozoal/viral), Tuberculosis (TB), and inflammatory bowel disease.

• ADALIMUMAB
• CERTOLIZUMAB
• FINGOLIMOD
• LEFLUNOMIDE
• BCG VACCINE
• DENGUE VACCINE

• Maintain a healthy body weight because obesity can lead to joint pain. Please avoid strenuous exercise as it may aggravate your arthritis-related joint pain. Instead, you can stretch and engage in low-impact aerobic exercises such as treadmill walking, biking, and swimming. Lifting light weights can also help improve your muscle strength.
• Increase your intake of glucosamine, chondroitin sulfate, vitamin D, and calcium-rich supplements. Aside from that, turmeric and fish oils can help reduce tissue inflammation.
• Include fish such as salmon, trout, tuna, and sardines in your diet if you have arthritis or joint pain. These fish are high in omega-3 fatty acids, which aid in the reduction of inflammation (redness and swelling) and the protection of the heart.
• Your sitting posture is critical, especially if you suffer from pain or inflammation. Try to sit as little as possible and only for a short period of time (10-15 min). To alleviate pain, place a rolled-up towel at the back of your curve. In addition, if necessary, a footrest can be used.
• Follow heat or cold therapy by applying a cold or hot compress to the joints on a regular basis for 15-20 minutes.
• Relax by meditating, reading, taking a nice bubble bath, or listening to calming music.
• Avoid drinking alcohol and quit smoking.

• It is advised to closely monitor the patient for infections like tuberculosis during and after the treatment, though the patient gets a negative tuberculin test.
• It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting Scapho 150Mg/Ml Inj.

Plaque psoriasis: Plaque psoriasis is a most common autoimmune condition in which skin cells multiply faster than normal, resulting in white scales and itchy, red, dry patches. Certain medications, infections, skin injury, stress, and tobacco or alcohol use are the common triggers for plaque psoriasis.

Psoriatic arthritis: It is a type of inflammatory arthritis which occurs in patients with psoriasis. It could also occur in patients without psoriasis, particularly in those with a family history of psoriasis. It affects large joints in the lower extremities, the distal joints of toes and fingers, and the back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin, and pain.

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints, or other body parts. Ankylosing spondylitis symptoms include decreased flexibility, which usually leads to a hunched-forward posture and pain in the back and joints.

Active non-radiographic axial spondyloarthritis: It is a persistent inflammatory disorder. It is characterized by active inflammation of the spine and sacroiliac (SI) joints, which connect the lower spine and pelvis.