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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Safefol-Plus Softgel Capsule is a vitamin supplement which is used to treat nutritional deficiencies, folic acid deficiency, vitamin B6 deficiency and vitamin B12 deficiency. It is a combination medicine which helps replenish energy, regulates many bodily functions, helps in the formation of red blood cells and provides essential nutrients that are required for the body's growth and development. This medicine may cause common side effects like stomach upset, diarrhoea, numbness/tingling, nausea, and vomiting.
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Manufacturer/Marketer

Zestica Pharma

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

About Safefol-Plus Softgel Capsule

Safefol-Plus Softgel Capsule is used to treat nutritional deficiencies. It is used to treat and prevent vitamin B6 deficiency, folate deficiency, and vitamin B12 deficiency. Nutritional deficiency occurs when the body is unable to absorb or get enough nutrients from food. It could lead to various health problems, including defective bone growth, anaemia, skin disorders, digestive issues, nerve disorders, and dementia (memory loss).

Safefol-Plus Softgel Capsule contains Docosahexaenoic acid, Folic acid, Pyridoxine and Methylcobalamin. Docosahexaenoic acid (DHA) is an omega fatty acid that controls cholesterol levels and thus improves cardiovascular health. Folic acid, a form of Vitamin B, helps in the formation of red blood cells and prevents DNA changes that may lead to cancer. Pyridoxine (vitamin B6) is involved in protein, fat, and carbohydrate metabolism, the formation of red blood cells and neurotransmitters. Methylcobalamin/Mecobalamin/Vitamin B12 regulates body functions, such as cell multiplication, blood formation, and protein synthesis. 

Your doctor will decide the duration based on your medical condition. Safefol-Plus Softgel Capsule may cause common side effects like stomach upset, diarrhoea, numbness/tingling, nausea, and vomiting. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult a doctor.

Let your doctor know if you use any other medications, including vitamins, before starting Safefol-Plus Softgel Capsule . Please tell your doctor if you are allergic to Safefol-Plus Softgel Capsule or other medicines. Inform your doctor beforehand if you have a history of liver, heart or kidney diseases. It is essential to let your doctor know if you are a pregnant or breastfeeding mother before using Safefol-Plus Softgel Capsule . It is advised to limit alcohol intake to avail maximum benefits of Safefol-Plus Softgel Capsule . Safefol-Plus Softgel Capsule is possibly safe when advised by a doctor to your child.

Uses of Safefol-Plus Softgel Capsule

Management and treatment of Nutritional deficiencies

Medicinal Benefits

Safefol-Plus Softgel Capsule is used to treat nutritional deficiencies. It contains Docosahexaenoic acid (DHA), Folic acid, Pyridoxine and Methylcobalamin. Docosahexaenoic acid (DHA) acts as an energy source and reduces the risk of heart diseases by lowering triglycerides and raising good cholesterol levels. Folic acid, a form of Vitamin B, helps in the formation of red blood cells and prevents DNA changes that may lead to cancer. Pyridoxine helps in cognitive development through the biosynthesis of neurotransmitters and maintains normal homocysteine levels (an amino acid in the blood). Methylcobalamin treats Vitamin B12 deficiency and regulates body functions like cell multiplication, blood formation, and protein synthesis. Collectively, Safefol-Plus Softgel Capsule treats nutritional deficiencies.

Directions for Use

Swallow Safefol-Plus Softgel Capsule as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Safefol-Plus Softgel Capsule

  • Nausea
  • Vomiting
  • Stomach upset
  • Diarrhoea
  • Numbness/tingling

Drug Warnings

Let your doctor know if you have any blood disorders like pernicious anaemia and malabsorption syndrome before starting Safefol-Plus Softgel Capsule . Pregnant and breastfeeding women should consult their doctor before taking Safefol-Plus Softgel Capsule . Excessive alcohol consumption reduces absorption and increases the elimination of folic acid. Alcohol can also worsen the side effects like stomach upset. Hence, please avoid alcohol while using Safefol-Plus Softgel Capsule . Safefol-Plus Softgel Capsule is possibly safe when advised by a doctor to your child.

Drug Interactions

Drug-Drug Interaction: Safefol-Plus Softgel Capsule may interact with anti-cancer drugs (altretamine, cisplatin, and arsenic trioxide), fits medicines (phenytoin, phenobarbital), antibiotic (chloramphenicol), medicines treating Parkinson's disease (levodopa), drugs used to treat tumours (Fluorouracil), antibiotics (trimethoprim), stomach related drugs (sulfasalazine), and cholesterol-lowering drugs (cholestyramine).

Drug-Food Interaction: Excessive alcohol consumption reduces the absorption and increases the elimination of folic acid. Hence, please avoid alcohol while using Safefol-Plus Softgel Capsule .

Drug-Disease Interaction: Use Safefol-Plus Softgel Capsule with medical advice if you have malabsorption syndrome (difficulty absorbing nutrition from food) and allergic reactions to medicines.

Drug-Drug Interactions Checker List

  • ALTRETAMINE
  • CISPLATIN
  • ARSENIC TRIOXIDE
  • PHENYTOIN
  • PHENOBARBITAL
  • CHLORAMPHENICOL
  • LEVODOPA
  • FLUOROURACIL
  • TRIMETHOPRIM
  • SULFASALAZINE
  • CHOLESTYRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, and salmon, shellfish, oysters, clams, dark green vegetables such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
  • Try folate-rich food sources like broccoli, Brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, and breakfast cereals fortified with folic acid.
  • Include fruits like citrus, banana, and watermelon in your diet.
  • Avoid smoking and alcohol consumption.
  • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.

Special Advise

  • Clinical monitoring of folic acid, vitamins B12 and B6 levels through blood examinations is recommended. 
  • Let your doctor and the laboratory staff know if you are using Safefol-Plus Softgel Capsule since Pyridoxine may interfere with laboratory tests like urine tests for urobilinogen. 

Disease/Condition Glossary

Nutritional deficiency: A nutritional deficiency occurs when the body does not absorb or get enough nutrients from food. This condition occurs when a person's nutrient intake is lesser than the body's recommended requirement. It can lead to various health problems like a weak immune system, skin problems, digestion problems, defective bone growth, and neurological diseases.

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Alcohol

Caution

Excessive alcohol consumption reduces the absorption and increases the elimination of folic acid. Hence, please avoid alcohol while using Safefol-Plus Softgel Capsule .

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Pregnancy

Caution

Safefol-Plus Softgel Capsule should be used during pregnancy only when advised by your doctor. Let your doctor know if you are pregnant or planning to conceive before taking Safefol-Plus Softgel Capsule .

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Breast Feeding

Caution

Pyridoxine and Folic acid are excreted into the breast milk. Please consult your doctor before taking Safefol-Plus Softgel Capsule if you are a breastfeeding mother.

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Driving

Safe

Safefol-Plus Softgel Capsule does not affect your driving ability.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Safefol-Plus Softgel Capsule .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Safefol-Plus Softgel Capsule .

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Children

Caution

The doctor will decide the dosage of Safefol-Plus Softgel Capsule based on the child's age and weight.

Country of origin

India
Other Info - SAF0409

Author Details

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FAQs

Safefol-Plus Softgel Capsule is used to treat nutritional deficiencies.
Safefol-Plus Softgel Capsule is a vitamin supplement and consists of Docosahexaenoic acid, Folic acid, Pyridoxine (vitamin B6), and Methylcobalamin (vitamin B12). When you lack these vitamins in your body, which cannot be recovered even with the food sources, Safefol-Plus Softgel Capsule helps replenish these deficient levels. Collectively, Safefol-Plus Softgel Capsule treats nutritional deficiencies.
Pyridoxine in Safefol-Plus Softgel Capsule may interfere with laboratory tests like urine tests for urobilinogen. Please make sure that the doctor and the laboratory staff know that you take Safefol-Plus Softgel Capsule before undergoing blood and urine examinations.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
It is advised to take Safefol-Plus Softgel Capsule with food to avoid any stomach upset. Please consult your doctor for more information.

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