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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 10:52 AM IST

Retromin-Iv Infusion is used in the treatment of HIV. It contains Zidovudine, which belongs to the protease nucleoside reverse transcriptase inhibitor (NRTI) class. It works by inhibiting the nucleoside reverse transcriptase enzymes necessary for the virus's DNA reproduction. Thus, it inhibits viral replication and thereby prevents the further spread of infection. It also helps improve the quality of life of a patient with HIV.

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Prescription drug

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Composition

ZIDOVUDINE-10MG

Manufacturer/Marketer

Retra Life Science Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Retromin-Iv Infusion

Retromin-Iv Infusion is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Symptoms of HIV include fever, chills, night sweats, muscle aches, etc. This medicine is also used for the prevention of maternal-fetal HIV transmission.

Retromin-Iv Infusion contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

Retromin-Iv Infusion may cause certain side effects such as nausea, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhoea, nasal congestion, fever, tiredness, muscle pain, dizziness, injection site reactions and pain at the injection site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Retromin-Iv Infusion will be administered by a trained healthcare professional in the hospital setting. Hence, do not self-administer

Retromin-Iv Infusion should be avoided if you are allergic to it. Before receiving this medicine, inform your doctor if you have heart problems, liver/kidney diseases, haematological toxicity, severe anaemia, hepatomegaly with steatosis, lactic acidosis, or peripheral nephropathy. If you are pregnant or breastfeeding, inform your doctor before taking this medicine. Consult your pediatrician about the use of Retromin-Iv Infusion in children. If prescribed, the child should be carefully monitored for any changes. Retromin-Iv Infusion is used to treat the infection but does not cure or prevent it. 

Uses of Retromin-Iv Infusion

Treatment of Human Immunodeficiency Virus (HIV) Infection

Medicinal Benefits

Retromin-Iv Infusion contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection. Retromin-Iv Infusion is used in the treatment of HIV infection and helps reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Directions for Use

A trained healthcare professional will administer Retromin-Iv Infusion . Hence, avoid self-administration.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Retromin-Iv Infusion

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Loss of appetite
  • Tiredness
  • Nasal congestion
  • Fever
  • Cough
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

Retromin-Iv Infusion should be avoided if you are allergic to it. Before receiving this medicine, inform your doctor if you have heart problems, liver/kidney diseases, haematological toxicity, severe anaemia, hepatomegaly with steatosis, lactic acidosis, or peripheral nephropathy. If you are pregnant or breastfeeding, inform your doctor before receiving Retromin-Iv Infusion . Consult your pediatrician about the use of Retromin-Iv Infusion in children. If prescribed, the child should be carefully monitored for any changes. Retromin-Iv Infusion is used to treat the infection but does not cure or prevent it. Inform your doctor about your medical history and the medicines you take to avoid possible interactions. Retromin-Iv Infusion may cause dizziness; hence, avoid driving vehicles or operating machines.

Drug Interactions

Drug-Drug Interactions: Retromin-Iv Infusion may interact with contraceptives (ethyl estradiol, norethindrone), immunosuppressants (cyclosporin, sirolimus, tacrolimus), antiretroviral drugs (stavudine, ritonavir), cytotoxic drugs (idarubicin, epirubicin, doxorubicin), antiviral medicine (ganciclovir).

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have cardiac problems, hepatomegaly with steatosis, lactic acidosis, and peripheral nephropathy before starting treatment with Retromin-Iv Infusion .

Drug-Drug Interactions Checker List

  • CYCLOSERINE
  • SIROLIMUS
  • TACROLIMUS
  • RITONAVIR
  • STAVUDINE
  • IDARUBICIN
  • EPIRUBICIN
  • GANCICLOVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration. 

Special Advise

  • Get an HIV test done at least every three months.
  • Regular kidney and liver function and bone mineral density tests while taking Retromin-Iv Infusion are advised. 
  • Regular blood tests should be done while receiving Retromin-Iv Infusion .
  • Retromin-Iv Infusion may still develop infections or other illnesses associated with HIV infection or AIDS. So, people receiving Retromin-Iv Infusion should be carefully monitored throughout the treatment.

Disease/Condition Glossary

HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. Retromin-Iv Infusion helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.

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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption while taking Retromin-Iv Infusion .

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Pregnancy

Consult your doctor

If you are pregnant or suspect you may be pregnant, inform your doctor before receiving Retromin-Iv Infusion . Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.

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Breast Feeding

Unsafe

Retromin-Iv Infusion is excreted in milk. You should not nurse your child if you are receiving this medicine because of the risk of HIV-1 transmission and serious adverse reactions in breastfeeding infants.

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Driving

Caution

Retromin-Iv Infusion will be administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

Retromin-Iv Infusion should be used with caution in patients with mild to moderate liver impairment. In case of severe liver problems, it may increase the risk of hematologic toxicity. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Retromin-Iv Infusion should be used with caution in patients with kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Consult your pediatrician about the use of Retromin-Iv Infusion in children. While this medication can be recommended for children as young as newborns for certain conditions, there are some precautions to take.

Country of origin

India

Manufacturer/Marketer address

201,Tarni Enclave Opp: Meher Sai School, Pama Nagar Phase II, Chintal-500054
Other Info - RET0192

FAQs

Retromin-Iv Infusion is used to treat Human Immunodeficiency Virus (HIV) Infection.
Retromin-Iv Infusion contains Zidovudine, which works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.
No, completing the entire treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.
Retromin-Iv Infusion doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.

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