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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Repatha SureClick Injection is in the treatment of primary hyperlipidemia (high cholesterol). It contains Evolocumab, which works by preventing the production of LDL cholesterol to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body. Thus, it helps to reduce the risk of heart attack, MI, stroke and other cardiovascular conditions.

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Prescription drug

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Manufacturer/Marketer

Dr Reddy's Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Repatha SureClick Injection

Repatha SureClick Injection belongs to the class of monoclonal antibodies. It is used alone or in combination with other medicines for the treatment of primary hyperlipidemia. It is also used to reduce the risk of myocardial infarction, heart attack, stroke, and coronary revascularization in adults with established cardiovascular disease

Repatha SureClick Injection contains Evolocumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the PCSK9-LDL receptor binding process and thereby helping to decrease LDL (low-density lipoprotein) levels in the blood.

Repatha SureClick Injection may cause certain side effects, such as nausea, vomiting, muscle spasms, arthralgia, fatigue, back pain, cough, injection site reactions, and pain at the site of injection. If these side effects bother you, inform your doctor. A trained healthcare professional will administer Repatha SureClick Injection. Hence, do not self-administer.

While taking Repatha SureClick Injection if you experience any allergic reactions, inform your doctor immediately. Before receiving this injection, inform your doctor if you have any pre-existing or a history of liver or kidney disease, skin problems, or any allergic conditions. Inform your physician if you are pregnant or breastfeeding before starting the treatment.

Uses of Repatha SureClick Injection

Treatment of Hyperlipidemia

Medicinal Benefits

Repatha SureClick Injection contains Evolocumab, which belongs to the class of proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor antibody. This medicine works by binding to the PCSK9 antibody and inhibits the PCSK9 and LDL receptor binding process. This helps decrease the LDL (low-density lipoprotein) levels in the blood. It is used to reduce the risk of heart attack, MI, stroke and other cardiovascular conditions.

Directions for Use

A trained healthcare professional will administer Repatha SureClick Injection. Hence, do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Repatha SureClick Injection

  • Nausea
  • Vomiting
  • Muscle spams
  • Arthralgia
  • Fatigue
  • Back pain
  • Cough
  • Upper respiratory symptoms
  • Injection site reactions

Drug Warnings

While taking Repatha SureClick Injection if you experience any allergic reaction, inform your doctor immediately. It is important to let your doctor know about your complete medical and medication history to rule out any allergic reactions. Before receiving this injection, inform your doctor if you have any pre-existing or a history of liver/kidney disease, skin problems, or any allergic conditions. Inform your physician if you are pregnant or breastfeeding before starting the treatment. Repatha SureClick Injection is not recommended for use in children as the safety and efficacy are not established. Lifestyle changes like a healthy low-fat diet, less salt intake, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction should be performed for better results.

Drug Interactions

Drug-Drug Interactions: Repatha SureClick Injection may interact with monoclonal antibodies (rozanolixizumab), vitamins, herbal supplements, and other medicines.

Drug-Food Interactions: Avoid alcohol consumption and smoking.

Drug-Disease Interactions: Inform your doctor if you have kidney or liver disease or skin diseases before receiving Repatha SureClick Injection.

Drug-Drug Interactions Checker List

  • ROZANOLIXIZUMAB

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products. 
  • Quitting smoking is the best strategy to lower the risk of heart disease. 
  • Avoid chronic stress. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques. 
  • Including heart-healthy omega-3 fatty acid-containing food drinks in your daily diet.

Special Advise

  • Your doctor may advise regular monitoring of liver and kidney function tests to monitor the liver and kidney functions.

Disease/Condition Glossary

Hyperlipidemia: Generally, your body contains bad cholesterol-low-density lipoprotein (LDL) and good cholesterol-high-density lipoprotein (HDL). Good cholesterol is good for our heart and helps in reducing the LDL in our body, whereas an excess of bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke. The high amount of bad cholesterol in the blood is known as hyperlipidemia, which results in narrow and clogged arteries. The blockage is most often caused by fat buildup and other substances, resulting in the formation of plaque in the arteries that feed the heart (coronary arteries). Eating high-fat or high-cholesterol-containing foods and drinks and genetic factors are the primary causes of high cholesterol.

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Alcohol

Consult your doctor

It is unknown whether Repatha SureClick Injection interacts with alcohol. Consult your doctor.

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Pregnancy

Caution

Limited data is available on the effect of Repatha SureClick Injection in pregnancy. Hence, if you are pregnant or planning to be pregnant, inform your doctor before receiving Repatha SureClick Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Repatha SureClick Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Repatha SureClick Injection may cause fatigue. Do not drive or operate machines if you experience any symptoms that may alter your alertness after taking Repatha SureClick Injection.

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Liver

Caution

No dose adjustment is required in case of mild to moderate liver impairment. However, if you have liver problems, inform your doctor before receiving Repatha SureClick Injection. No data are available on the usage of Repatha SureClick Injection in patients with severe liver impairment.

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Kidney

Caution

No dose adjustment is required in patients with kidney impairment. However, if you have kidney problems, inform your doctor before receiving Repatha SureClick Injection.

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Children

Unsafe

Repatha SureClick Injection is not recommended for use in children as the safety and efficacy are not established.

Manufacturer/Marketer address

Tirath Nagar, Badi Majra, Yamunanagar Road, Ambala, Haryana, 135001, India
Other Info - RE46928

FAQs

Repatha SureClick Injection is used to treat Hyperlipidemia.
Repatha SureClick Injection works by inhibiting the PCSK9- LDL receptor binding process and thereby helps decrease the LDL (low-density lipoprotein) levels in the blood.

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