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Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Repatha SureClick Injection is in the treatment of primary hyperlipidemia (high cholesterol). It contains Evolocumab, which works by preventing the production of LDL cholesterol to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body. Thus, it helps to reduce the risk of heart attack, MI, stroke and other cardiovascular conditions.

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Prescription drug

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Composition :

EVOLOCUMAB-140MG/ML

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Repatha SureClick Injection

Repatha SureClick Injection belongs to the class of monoclonal antibodies. It is used alone or in combination with other medicines for the treatment of primary hyperlipidemia. It is also used to reduce the risk of myocardial infarction, heart attack, stroke, and coronary revascularization in adults with established cardiovascular disease

Repatha SureClick Injection contains Evolocumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the PCSK9-LDL receptor binding process and thereby helping to decrease LDL (low-density lipoprotein) levels in the blood.

Repatha SureClick Injection may cause certain side effects, such as nausea, vomiting, muscle spasms, arthralgia, fatigue, back pain, cough, injection site reactions, and pain at the site of injection. If these side effects bother you, inform your doctor. A trained healthcare professional will administer Repatha SureClick Injection. Hence, do not self-administer.

While taking Repatha SureClick Injection if you experience any allergic reactions, inform your doctor immediately. Before receiving this injection, inform your doctor if you have any pre-existing or a history of liver or kidney disease, skin problems, or any allergic conditions. Inform your physician if you are pregnant or breastfeeding before starting the treatment.

Uses of Repatha SureClick Injection

Treatment of Hyperlipidemia

Medicinal Benefits

Repatha SureClick Injection contains Evolocumab, which belongs to the class of proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor antibody. This medicine works by binding to the PCSK9 antibody and inhibits the PCSK9 and LDL receptor binding process. This helps decrease the LDL (low-density lipoprotein) levels in the blood. It is used to reduce the risk of heart attack, MI, stroke and other cardiovascular conditions.

Side Effects of Repatha SureClick Injection

  • Nausea
  • Vomiting
  • Muscle spams
  • Arthralgia
  • Fatigue
  • Back pain
  • Cough
  • Upper respiratory symptoms
  • Injection site reactions

Directions for Use

A trained healthcare professional will administer Repatha SureClick Injection. Hence, do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

While taking Repatha SureClick Injection if you experience any allergic reaction, inform your doctor immediately. It is important to let your doctor know about your complete medical and medication history to rule out any allergic reactions. Before receiving this injection, inform your doctor if you have any pre-existing or a history of liver/kidney disease, skin problems, or any allergic conditions. Inform your physician if you are pregnant or breastfeeding before starting the treatment. Repatha SureClick Injection is not recommended for use in children as the safety and efficacy are not established. Lifestyle changes like a healthy low-fat diet, less salt intake, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction should be performed for better results.

Therapeutic Class

MONOCLONAL ANTIBODIES

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products. 
  • Quitting smoking is the best strategy to lower the risk of heart disease. 
  • Avoid chronic stress. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques. 
  • Including heart-healthy omega-3 fatty acid-containing food drinks in your daily diet.

Habit Forming

No

How Repatha SureClick Injection Works

Repatha SureClick Injection contains Evolocumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the PCSK9-LDL receptor binding process and thereby helping to decrease LDL (low-density lipoprotein) levels in the blood.

What if I have taken an overdose of Repatha SureClick Injection

As Repatha SureClick Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose of Repatha SureClick Injection or observe any adverse events, get medical care right away.
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Alcohol

Consult your doctor

It is unknown whether Repatha SureClick Injection interacts with alcohol. Consult your doctor.

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Pregnancy

Caution

Limited data is available on the effect of Repatha SureClick Injection in pregnancy. Hence, if you are pregnant or planning to be pregnant, inform your doctor before receiving Repatha SureClick Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Repatha SureClick Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Repatha SureClick Injection may cause fatigue. Do not drive or operate machines if you experience any symptoms that may alter your alertness after taking Repatha SureClick Injection.

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Liver

Caution

No dose adjustment is required in case of mild to moderate liver impairment. However, if you have liver problems, inform your doctor before receiving Repatha SureClick Injection. No data are available on the usage of Repatha SureClick Injection in patients with severe liver impairment.

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Kidney

Caution

No dose adjustment is required in patients with kidney impairment. However, if you have kidney problems, inform your doctor before receiving Repatha SureClick Injection.

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Children

Unsafe

Repatha SureClick Injection is not recommended for use in children as the safety and efficacy are not established.

Manufacturer/Marketer address

Tirath Nagar, Badi Majra, Yamunanagar Road, Ambala, Haryana, 135001, India
Other Info - RE46928

Author Details

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FAQs

Repatha SureClick Injection is used to treat Hyperlipidemia.
Repatha SureClick Injection works by inhibiting the PCSK9- LDL receptor binding process and thereby helps decrease the LDL (low-density lipoprotein) levels in the blood.

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