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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
RENOCEL 4000IU INJECTION 1.0ML is used to treat anaemia due to chronic kidney disease and chemotherapy. It contains Erythropoietin alfa, human recombinant which works by stimulating the bone marrow to make more red blood cells. This medicine may sometimes cause side effects such as high blood pressure, nausea, vomiting and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Celestial Biologicals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About RENOCEL 4000IU INJECTION 1.0ML

RENOCEL 4000IU INJECTION 1.0ML belongs to a class of drugs known as erythropoiesis-stimulating agent (ESA) primarily used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and anaemia due to chemotherapy (cancer treatment). Anaemia is reduced levels of haemoglobin and red blood cells (RBCs) in the blood. Chronic kidney disease (CKD) patients slowly develop anaemia, which gets worse as the disease progresses. Also, the treatment of cancer, including chemotherapy and radiotherapy, causes anaemia in cancer patients.

RENOCEL 4000IU INJECTION 1.0ML contains ‘Erythropoietin alfa, human recombinant’. RENOCEL 4000IU INJECTION 1.0ML works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This RENOCEL 4000IU INJECTION 1.0ML is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC), preventing anaemia (lack of haemoglobin and RBC in the blood).

RENOCEL 4000IU INJECTION 1.0ML will be administered by a healthcare professional; do not self-administer. You may experience high blood pressure, nausea, vomiting and fever. Most of these side effects of RENOCEL 4000IU INJECTION 1.0ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to RENOCEL 4000IU INJECTION 1.0ML or any other medicines, please tell your doctor. RENOCEL 4000IU INJECTION 1.0ML should not be taken in conditions like heart disease, high blood pressure, or liver disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using RENOCEL 4000IU INJECTION 1.0ML. RENOCEL 4000IU INJECTION 1.0ML may affect your ability to drive and use machines as RENOCEL 4000IU INJECTION 1.0ML may cause fits disorder during the first 90 days of treatment. 

Uses of RENOCEL 4000IU INJECTION 1.0ML

Treatment of Anemia due to chronic kidney disease, Anemia due to chemotherapy.

Medicinal Benefits

RENOCEL 4000IU INJECTION 1.0ML helps in the treatment of anemia which may happen due to chronic kidney disease and cancer chemotherapy. RENOCEL 4000IU INJECTION 1.0ML works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This RENOCEL 4000IU INJECTION 1.0ML is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood). Besides this RENOCEL 4000IU INJECTION 1.0ML is also used for the treatment of anemia caused by a medicine known as zidovudine for the treatment of HIV (human immunodeficiency viruses). RENOCEL 4000IU INJECTION 1.0ML also decreases the requirement for blood cell transfusions.

Directions for Use

RENOCEL 4000IU INJECTION 1.0ML will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RENOCEL 4000IU INJECTION 1.0ML

  • High blood pressure
  • Nausea
  • Vomiting
  • Fever
  • Joint pain
  • Clotting at the injection site

Drug Warnings

If you are known to be allergic to RENOCEL 4000IU INJECTION 1.0ML or any other medicines, please tell your doctor. RENOCEL 4000IU INJECTION 1.0ML should not be taken in conditions like high blood pressure, heart disease, heart attack, blood clot in the brain (stroke), fits disorder, liver disease, or kidney disease. Before taking RENOCEL 4000IU INJECTION 1.0ML inform your doctor if you have any type of cancer or skin reactions. If you are pregnant or a nursing mother, it is advised to consult a doctor before using RENOCEL 4000IU INJECTION 1.0ML. RENOCEL 4000IU INJECTION 1.0ML may affect your ability to drive and using machines as RENOCEL 4000IU INJECTION 1.0ML may cause fits to disorder during the first 90 days of treatment. RENOCEL 4000IU INJECTION 1.0ML should not be used for children below 1 month of age during treatment of anemia due to chronic kidney disease. RENOCEL 4000IU INJECTION 1.0ML should not be used for children below 5 years of age during treatment of anemia due to chemotherapy.

Drug Interactions

Drug-Drug Interactions: RENOCEL 4000IU INJECTION 1.0ML may have interaction with medicines used after kidney transplant (cyclosporine), other medicines for cancer and anemia (lenalidomide), medicines used for skin disease and cancer (thalidomide), anticancer (pomalidomide).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: RENOCEL 4000IU INJECTION 1.0ML should not be used in patients with high blood pressure and fits disorder.

Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • LENALIDOMIDE
  • THALIDOMIDE
  • POMALIDOMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  • Your doctor may get your blood tests done frequently to examine the levels of blood cells, hemoglobin, and electrolytes such as potassium in your blood.
  • Eat food that is rich in iron, vitamin B12, and folic acid.
  • Eat food like leafy, green vegetables, fish, eggs, and liver.
  • Do mild to moderate exercise.

Disease/Condition Glossary

Anemia due to chronic kidney disease: Anemia describes reduced levels of hemoglobin and red blood cells (RBCs) in the blood. Chronic kidney disease (CKD) patients slowly develop anemia, which gets worse as the disease progresses. Then the kidneys partially lose their functions permanently in CKD. There is not sufficient erythropoietin (hormone formed by kidneys and produced RBC) formation. This hormone helps the production of RBCs by the bone marrow. As a result, RBC production is affected, leading to fewer RBCs than normal.

Anemia due to chemotherapy: Some types of cancer that affect blood and bone marrow, like blood cancer, and bone marrow cancer can decrease red blood cells. Also, the treatment of cancer, including chemotherapy and radiotherapy, causes anemia in cancer patients. This happens when a few medicines or radiation kill the red blood cells with the cancerous cells.

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Alcohol

Caution

It is not known that RENOCEL 4000IU INJECTION 1.0ML may interact with alcohol. Therefore, avoid drinking alcohol while using RENOCEL 4000IU INJECTION 1.0ML.

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Pregnancy

Caution

RENOCEL 4000IU INJECTION 1.0ML should not be taken until prescribed. Your doctor will decide what is the best treatment for you. Please consult your doctor.

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Breast Feeding

Caution

Inform your doctor before taking RENOCEL 4000IU INJECTION 1.0ML. Your doctor will advise you to either stop or continue treatment.

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Driving

Caution

RENOCEL 4000IU INJECTION 1.0ML may affect your ability to drive and using machines as RENOCEL 4000IU INJECTION 1.0ML may cause fits to disorder during the first 90 days of treatment.

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Liver

Caution

Take RENOCEL 4000IU INJECTION 1.0ML with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

RENOCEL 4000IU INJECTION 1.0ML is safely given to the kidney patients only if prescribed by your doctor.

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Children

Caution

RENOCEL 4000IU INJECTION 1.0ML should be used in children only when prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Plot No. 496/1/A & B, Sarkhej-Bavla Highway Village: Matoda, Taluka: Sanand Ahmedabad GJ 382210 IN
Other Info - REN0149

FAQs

RENOCEL 4000IU INJECTION 1.0ML is used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and chemotherapy (cancer treatment).
Yes, RENOCEL 4000IU INJECTION 1.0ML can be used for children above 1 month of age during treatment of anemia due to chronic kidney disease. RENOCEL 4000IU INJECTION 1.0ML can be used for children above 5 years of age during treatment of anemia due to chemotherapy. The effectiveness of RENOCEL 4000IU INJECTION 1.0ML and side effects observed in children is the same as adults, and used only when prescribed by a doctor.
Yes, RENOCEL 4000IU INJECTION 1.0ML may increase the blood pressure. During initial treatment with RENOCEL 4000IU INJECTION 1.0ML, blood pressure should be examined and those who have high blood pressure should take proper methods to regulate blood pressure. Your doctor may stop RENOCEL 4000IU INJECTION 1.0ML if the blood pressure continues uncontrolled.
RENOCEL 4000IU INJECTION 1.0ML works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This RENOCEL 4000IU INJECTION 1.0ML is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood).
The most common side effects of RENOCEL 4000IU INJECTION 1.0ML are high blood pressure, nausea, vomiting, and fever, diarrhea, feeling upset in the stomach, skin rashes, stuffy nose, sore throat, bone, or muscle pain. Most of these side effects of RENOCEL 4000IU INJECTION 1.0ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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