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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:26 PM IST
R Cin 600 Capsule is used in combination with other medicines to treat tuberculosis (TB). It contains Rifampicin, which inhibits the growth of bacteria. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness or tingling sensation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

RIFAMPICIN-600MG

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About R Cin 600 Capsule

R Cin 600 Capsule is used in combination with other medicines to treat tuberculosis (TB). Tuberculosis is an infectious respiratory disease that affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. It is also used to treat other bacterial infections. R Cin 600 Capsule does not work against infections caused by the virus, including cold and flu. As R Cin 600 Capsule is an antibiotic, it does not work against infections caused by the virus, including cold and flu. The bacteria causing tuberculosis (TB) are highly contagious and spread from one person to another via tiny droplets released into the air (through coughs or sneezes).

R Cin 600 Capsule consists of a drug called 'rifampicin', which works by inactivating a bacterial protein enzyme (RNA-polymerase) and inhibits bacterial cell death.  R Cin 600 Capsule acts against the bacteria called Mycobacterium tuberculosis, which causes TB (tuberculosis). 

R Cin 600 Capsule should be taken as recommended by your doctor. It should be taken 30 minutes before food or 2 hours after food on an empty stomach. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness or tingling sensation. Most of these side effects are mild and subside over time. However, if any of these effects persist, contact your doctor immediately.

R Cin 600 Capsule may raise liver enzymes like ALT and can cause jaundice if taken longer. Hence, a regular liver function test (LFT) is recommended while taking treatment with R Cin 600 Capsule. Maintain a gap of one hour between R Cin 600 Capsule and antacid medicines. R Cin 600 Capsule is not recommended if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking R Cin 600 Capsule as it passes into breast milk. R Cin 600 Capsule may cause dizziness, and vision problems; hence avoid driving vehicles or operating machines that require mental concentration. Avoid alcohol consumption while taking R Cin 600 Capsule as it could lead to increased drowsiness, dizziness, and liver damage.

Uses of R Cin 600 Capsule

Treatment of Tuberculosis (TB)

Medicinal Benefits

R Cin 600 Capsule contains 'Rifampicin' that treats Tuberculosis (TB) by inactivating a bacterial genetic material that allows TB bacteria to make a copy of its protein for further growth inside the host cell (human). R Cin 600 Capsule is active against gram-positive cocci bacteria like Mycobacteria and Clostridium difficle and gram-negative bacteria like Neisseria meningitides, N. gonorrhoeae and Hemophilus influenzae. R Cin 600 Capsule is also used as a second-line treatment in the treatment of cholestatic pruritus. It also treats leprosy and severe gram-positive bacterial infections (like osteomyelitis, endocarditis, brain abscess, meningitis and implant infections) in combination with other antibiotics. 

Directions for Use

Tablet/Capsule: Take R Cin 600 Capsule 30 minutes before or 2 hours after food on an empty stomach. Swallow R Cin 600 Capsule as a whole; do not crush or chew the tablet/capsule. The dose and duration of R Cin 600 Capsule can vary depending on your condition and the severity of the infection.Dispersible tablet (DT): Before taking this, take a glass of water, disperse the tablet in it and then drink it.Suspension: Shake the bottle well. It can be taken 30 minutes before or 2 hours after food on an empty stomach. The dose and duration of R Cin 600 Capsule can vary depending on your condition and the severity of the infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of R Cin 600 Capsule

  • Drowsiness
  • Dizziness 
  • Headache 
  • Weakness
  • Muscle pain
  • Heartburn 
  • Diarrhoea 
  • Gas 
  • Numbness or tingling sensation 

Drug Warnings

R Cin 600 Capsule should be avoided if you are allergic to any of its contents. Inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems on priority before starting treatment with R Cin 600 Capsule. Avoid foods and drinks containing histamines or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while treating with R Cin 600 Capsule as they might cause interaction. Maintain a gap of one hour between R Cin 600 Capsule and antacid medicines.

R Cin 600 Capsule is not recommended for pregnant women. Hence, inform your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while using R Cin 600 Capsule as it passes into breast milk. R Cin 600 Capsule should be given to children only if prescribed by the paediatrician. R Cin 600 Capsule may cause dizziness or drowsiness, so avoid driving vehicles. Avoid alcohol consumption along with R Cin 600 Capsule as it could lead to increased drowsiness, dizziness and liver damage.

Drug Interactions

DRUG-DRUG INTERACTIONS: R Cin 600 Capsule may have interaction with pain killers (acetaminophen, hydrocodone), anti-TB (ethambutol, pyrazinamide) and vitamins (ergocalciferol, cholecalciferol, ascorbic acid), blood thinners (warfarin), Antacids (Pantoprazole, omeprazole), Antibiotics (doxycycline, ciprofloxacin, amoxicillin), cough syrups (diphenhydramine), anti-seizure drugs  ( phenytoin, phenobarbital, Iamotrigine),  azole antifungals (itraconazole, ketoconazole, voriconazole), calcium channel blockers (diltiazem, nimodipine, verapamil).

FOOD-DRUG INTERACTIONS: Do not consume alcohol while taking R Cin 600 Capsule as it could lead to increased dizziness and liver damage. Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking R Cin 600 Capsule as they might cause interaction.

DRUG-DISEASE INTERACTION: R Cin 600 Capsule may have interactions with colitis (inflammation in the lining of the colon),  porphyria ( blood disease), hemodialysis, liver toxicity, and kidney and liver dysfunction.

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • HYDROCODONE
  • ERGOCALCIFEROL
  • ASCORBIC ACID
  • CHOLECALCIFEROL
  • WARFARIN
  • PANTOPRAZOLE
  • DOXYCYCLINE
  • CIPROFLOXACIN
  • AMOXICILLIN
  • DIPHENHYDRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try to take foods rich in vitamin C such as orange, kiwi, broccoli, and bell pepper which helps in improving the immune system. 

  • Avoid consuming processed and fried foods.

  • Warm ginger tea or warm soup can help in providing relief from cough.

  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.

  • Smoking and alcohol consumption should be avoided as it causes dizziness.

  • Drinking pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

Special Advise

  • R Cin 600 Capsule may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.

  • R Cin 600 Capsule may cause temporary discolouration of urine, tears, and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discoloured. Contact your doctor for further advice.

  • Regular liver tests may be advised by your doctor while taking R Cin 600 Capsule to check how your liver is functioning.

  • R Cin 600 Capsule may affect test results of some blood tests such as folate, vitamin B12, and liver function tests. Hence inform your doctor or the lab person if any such tests are advised.

Disease/Condition Glossary

Tuberculosis (TB): It is an infectious disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

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Alcohol

Caution

R Cin 600 Capsule intake is not recommended with alcohol. A patient is not advised to take alcohol with R Cin 600 Capsule as it may increase chances of liver damage.

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Pregnancy

Unsafe

Not recommended during pregnancy. Tell your doctor if you are pregnant or planning to become pregnant. R Cin 600 Capsule should not be taken during pregnancy as it can affect your unborn baby's growth and may cause complications to the mother and baby after birth.

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Breast Feeding

Unsafe

Not recommended while breastfeeding. A patient should not breast-feed while taking R Cin 600 Capsule. This is because a small amount of R Cin 600 Capsule may pass into the mother’s milk. So, if you are breastfeeding or planning to breast-feed, talk to your doctor.

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Driving

Caution

Caution should be maintained by a patient while driving a motor vehicle or doing hazardous work. A patient may experience dizziness, have problems with vision or have other side effects that could affect his ability to drive after taking this medicine. If this happens, do not drive.

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Liver

Caution

Not recommended to be taken in liver patients without doctors consultation as R Cin 600 Capsule has been found to affect liver function with raised ALT enzymes.

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Kidney

Caution

Not recommended for kidney patients without doctor's consultation. Intake of R Cin 600 Capsule in these people may result in symptoms like blood in the urine, a change in the amount of urine passed and feeling drowsy or weak.

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Children

Safe if prescribed

R Cin 600 Capsule is safe to be prescribed in children below 12 years. Dose adjustments by the doctor are done according to age, weight, and severity of infection

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RCI0003

Author Details

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FAQs

R Cin 600 Capsule belongs to the group of medicines called macrolide antibiotics, primarily used to treat tuberculosis (TB).
Do not stop taking R Cin 600 Capsule despite symptomatic relief. To treat your condition effectually, continue taking R Cin 600 Capsule for as long as it has been prescribed by doctor and must be taken strictly at proper times.
R Cin 600 Capsule is a bactericidal drug that means it kills bacteria. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for bacterial survival, thereby killing the bacteria.
R Cin 600 Capsule has no known serious drug interaction with ibuprofen or aspirin. Inform your doctor about all the medication you are currently taking to avoid harmful interactions that may reduce treatment effectiveness.
Yes, in some cases headache can be caused as a side effect of R Cin 600 Capsule. A patient must consult a doctor if it progresses with time.
R Cin 600 Capsule is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with R Cin 600 Capsule. Please consult your doctor if you have any liver problems before taking R Cin 600 Capsule as it may worsen the situation. However, prolonged use of R Cin 600 Capsule can cause raised ALT (liver enzyme), and the person taking the treatment can developed jaundice symptoms like yellowing of eye, skin etc. In this case, stop taking R Cin 600 Capsule and immediately contact a doctor.
R Cin 600 Capsule may cause temporary discoloration of urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored. Contact your doctor for further advice.
No, R Cin 600 Capsule is not a penicillin, amoxicillin, or sulfa drug. It is an antibiotic in the rifamycin class, combined with other medicines to treat tuberculosis.
R Cin 600 Capsule is an inducer (increases enzyme activity) of cytochrome P450 enzymes.
R Cin 600 Capsule may lead to side effects like weight loss, hair loss, and yeast infections, though constipation is less common. Consult your doctor if you experience any of these effects.
R Cin 600 Capsule causes side effects such as drowsiness, dizziness, headache, muscle pain, weakness, heartburn, diarrhoea, gas, and numbness or tingling sensation. Most of these are temporary and do not require any medical attention, as they will gradually reduce over time. Please contact a doctor if these persist for longer periods.

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