Rasilez 300 mg Tablet belongs to the class of drugs called direct renin inhibitors used in the treatment of essential hypertension. Essential hypertension is high blood pressure without a known secondary cause. 

Rasilez 300 mg Tablet contains Aliskiren which works by inhibiting the action of renin, an enzyme that helps the body to make angiotensin I, which is converted to angiotensin II (tightens and narrows blood vessels which increases the blood pressure). Thus, it reduces the production of angiotensin I and II. This helps to relax and widen the blood vessels and lower blood pressure. 

Take Rasilez 300 mg Tablet as prescribed. Your doctor will advise how often you take Rasilez 300 mg Tablet based on your medical condition. Sometimes, Rasilez 300 mg Tablet may cause common side effects such as dizziness, headache, back pain, diarrhoea, high levels of potassium in the blood or tiredness. Most of these side effects of Rasilez 300 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Aliskiren or any other ingredients of Rasilez 300 mg Tablet or if you have ever had a reaction called angioedema (swelling of the face, lips, tongue, throat, arms, and legs, and may cause difficulty breathing) to an ACE inhibitor medicine, inform your doctor. Rasilez 300 mg Tablet is not recommended for pregnant women, especially in the second and third trimesters, as it may cause injury and death to the developing fetus. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Rasilez 300 mg Tablet. Rasilez 300 mg Tablet is not recommended for children below 18 years as the safety and effectiveness were not established. 

Rasilez 300 mg Tablet contains Aliskiren used in the treatment of essential hypertension (high blood pressure). It inhibits the action of renin, an enzyme that helps the body to produce angiotensin II (tightens and narrows blood vessels which increases blood pressure). Thus, it reduces the production of angiotensin II. This helps to relax and widen the blood vessels and lower blood pressure. Thereby, it helps to reduce the risk of heart failure, stroke, heart attack or kidney failure.

• Dizziness
• Headache
• Back pain
• Diarrhoea
• High levels of potassium in the blood
• Tiredness

If you are allergic to Aliskiren or any other ingredients of Rasilez 300 mg Tablet or if you have ever had a reaction called angioedema (swelling of the face, lips, tongue, throat, arms, and legs, and may cause difficulty breathing) to an ACE inhibitor medicine, inform your doctor. Rasilez 300 mg Tablet is not recommended for pregnant women, especially in the second and third trimesters, as it may cause injury and death to the developing fetus. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Rasilez 300 mg Tablet. Rasilez 300 mg Tablet is not recommended for children below 18 years as the safety and effectiveness were not established. Do not consume alcohol with Rasilez 300 mg Tablet as it may worsen dizziness. Avoid potassium supplements with Rasilez 300 mg Tablet as they may lead to high potassium levels in the blood. If you have severe and persistent diarrhoea, you are recommended to stop taking Rasilez 300 mg Tablet.

Drug-Drug Interactions: If you are taking a medicine used to lower cholesterol in the blood (atorvastatin), water pills (furosemide, torasemide), antifungals (ketoconazole), immunosuppressant (cyclosporine), nonsteroidal anti-inflammatory drugs (ibuprofen, naproxen), high blood pressure lowering medicines (lisinopril, enalapril, ramipril, verapamil, telmisartan, valsartan, irbesartan), potassium-containing medicines, potassium supplements, or salt substitutes containing potassium, inform your doctor before taking Rasilez 300 mg Tablet.

Drug-Food Interactions: Avoid taking Rasilez 300 mg Tablet with fruit juice and/or drinks containing plant extracts (including herbal teas), as it may decrease the effectiveness of Rasilez 300 mg Tablet.

Drug-Disease Interactions: Avoid taking Rasilez 300 mg Tablet if you have experienced hereditary or idiopathic (without any known cause) angioedema (swelling of the lips, face, throat, tongue, arms, and legs, and may cause difficulty breathing). Inform your doctor if you have diabetes, impaired kidney function, renal artery stenosis (narrowing of the blood vessels to one or both kidneys), or serious congestive heart failure (heart cannot pump enough blood around the body) before taking Rasilez 300 mg Tablet.

• ATORVASTATIN
• FUROSEMIDE
• TORASEMIDE
• KETOCONAZOLE
• CYCLOSPORINE
• IBUPROFEN
• NAPROXEN
• LISINOPRIL
• ENALAPRIL
• RAMIPRIL
• VERAPAMIL
• TELMISARTAN
• VALSARTAN
• IRBESARTAN

• Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
• Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day.
• Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
• Maintain a diet that is rich in fruits, vegetables, whole grains and low-fat dairy products.
• Avoid smoking and alcohol intake.

• Your blood pressure, kidney function, and the amount of electrolytes (e.g. potassium) in your blood may be monitored by your doctor at regular intervals.

Essential hypertension: It is high blood pressure without a known secondary cause. Hypertension (high blood pressure) is a medical condition in which the blood pressure is elevated persistently in the arteries. High blood pressure is mostly caused by obesity, diabetes, smoking, high salt intake, stress, lack of physical activity, or ageing. Normal blood pressure lies between 90/60 mmHg and 120/80 mmHg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure. If it is left untreated, it may lead to heart disease and stroke.