Prothiaden M 50 Tablet belongs to the class of medications called antidepressants used in the treatment of depression. Depression is a neurological disease. It is a mood disorder characterized by persistent feelings of sadness, loss, or anger. This condition can also be triggered by vitamin b12 deficiency. Your doctor prescribes Prothiaden M 50 Tablet  when other medications are ineffective to treat depression. 

Prothiaden M 50 Tablet is a combination of two medicines: Dosulepine and Methylcobalamin. Dosulepin is a tricyclic antidepressant that increases neurotransmitter's activity, namely serotonin, and noradrenaline in the brain. Serotonin helps in enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. Noradrenaline helps in improving mood, alertness, and the ability to concentrate. Methylcobalamin helps to treat vitamin b12 deficiency.

The dose is determined by your doctor based on your health condition. The common side-effects of Prothiaden M 50 Tablet are dry mouth, blurred vision, headache, increase or decrease in appetite, nausea or vomiting, diarrhoea, changes in heartbeat, constipation, difficulty in passing urine, and sweating. If the symptoms persist or worsen, consult a doctor immediately.

Do not take Prothiaden M 50 Tablet if you are allergic to any content of it. Do not take Prothiaden M 50 Tablet if you have an irregular heartbeat or any other heart problems, liver problems, eye condition known as glaucoma, prostate problems in men (difficulty in passing water or enlarged prostate), mania (feeling over-excited with unusual behaviour), and epilepsy (fits). It should be used with caution in young adults as it can increase worsen depression and cause suicidal thoughts. If you have thoughts of harming yourself, consult your doctor immediately. Inform your doctor if you are pregnant or breastfeeding. 

Prothiaden M 50 Tablet is a combination of two medicines: Dosulepine and Methylcobalamin. Your doctor prescribes this medication when other medications are ineffective to treat depression. Dosulepin is a tricyclic antidepressant that increases neurotransmitters' activity, namely serotonin, and noradrenaline in the brain. Serotonin helps in enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. Noradrenaline helps in improving mood, alertness, and the ability to concentrate. Methylcobalamin helps to treat vitamin b12 deficiency.

• Dry mouth
• Blurred vision
• Headache
• Increase or decrease in appetite
• Nausea or vomiting
• Diarrhoea
• Changes in heartbeat
• Constipation
• Difficulty in passing urine
• Sweating

Before taking Prothiaden M 50 Tablet , inform your doctor if you are undergoing surgery, have diabetes, receiving electroshock therapy (ECT), have thyroid problems, difficulty in passing urine, adrenal gland tumour, have porphyria (disease-causing damage to the nerves and skin sensitivity), have a history of mania or psychosis, have cardiac disease, have severe renal disease, and have epilepsy (fits). It increases suicidal tendencies, especially in young adults.

Drug-Drug Interaction: Prothiaden M 50 Tablet may interact with other antidepressants, antihypertensives, medications used to treat heart disorders, antacid (omeprazole and cimetidine), antimalarial drug (halofantrine), antiallergy medicines (terfenadine and astemizole), pain killer (tramadol), local anaesthetics, antiepileptic drugs (phenytoin, primidone, and carbamazepine), estrogen-containing birth control pills, anticoagulant (warfarin), a medicine used to treat HIV (ritonavir), antibiotic (neomycin), and antibacterial (rifampicin).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Prothiaden M 50 Tablet should not be used in patients with heart disorders, liver problems, glaucoma (an eye condition), prostate problems in men, mania (feeling over-excited with unusual behaviour), and epilepsy (fits).

• OMEPRAZOLE
• CIMETIDINE
• HALOFANTRINE
• TERFENADINE
• ASTEMIZOLE
• TRAMADOL
• PHENYTOIN
• PRIMIDONE
• CARBAMAZEPINE
• WARFARIN
• RITONAVIR
• NEOMYCIN
• RIFAMPICIN

• Eat a well-balanced diet.
• Avoid processed or packed foods and foods that are high in refined sugars.
• Exercise regularly.
• Lose excess weight and keep a check on your weight.
• Avoid stress.
• Improve your mood by being active, socializing with others, and talking about your feelings.
• Quit alcohol intake and smoking.

Depression: Depression is a mental health disorder in which patients experience persistent loss of interest or mood and feelings of sadness. It affects quality-of-life. It causes changes in sleep, appetite, social behaviour, learning abilities, concentration, and self-esteem. This condition can also be triggered by vitamin B12 (cyanocobalamin) deficiency.