Prem-SR Tablet 10's belongs to a group of medications known as 'anticonvulsants' used to manage neuropathic pain due to damaged nerves. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. 

Prem-SR Tablet 10's is a combination of two drugs: Methylcobalamin/Mecobalamin (vitamin B12) and Pregabalin (anti-convulsant). Mecobalamin protects nerve fibres and rejuvenates nerve cells by producing a substance called myelin. Pregabalin works by changing how nerves send messages to the brain. Together, Prem-SR Tablet 10's helps to treat neuropathic pain (pain due to nerve damage). 

Take Prem-SR Tablet 10's as prescribed by your doctor. Depending on your medical condition, you are advised to take Prem-SR Tablet 10's for as long as your doctor has prescribed it for you. In some cases, you may experience common side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, dry mouth, dizziness, sleepiness, and uncoordinated body movements. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Prem-SR Tablet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Prem-SR Tablet 10's causes drowsiness and dizziness, so drive only if you are alert. Prem-SR Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Prem-SR Tablet 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Let your doctor know if you have a history of heart disease, severe kidney disease, disorders of the stomach or gut/bowel, and diabetes before using the Prem-SR Tablet 10's. 

Prem-SR Tablet 10's is a combination of two drugs: Mecobalamin and Pregabalin. Mecobalamin is used to restore vitamin B12 in the body to treat damaged nerve conditions due to diabetes or other traumatic situations. It also has a neuroprotective activity that helps the nerve cells to function properly and treat neuropathic pain. On the other side, Pregabalin prevents neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma or epilepsy. Together, Prem-SR Tablet 10's helps to treat neuropathic pain.

• Nausea
• Vomiting
• Stomach pain
• Diarrhea
• Heartburn
• Dryness in mouth
• Dizziness
• Blurred vision

Please do not stop taking Prem-SR Tablet 10's without consulting your doctor as it could cause withdrawal symptoms. Women of child-bearing potential should use effective contraception.  Inform your doctor before taking Prem-SR Tablet 10's if you have heart problems, bipolar syndrome, severe liver disease or porphyria, diabetes, and asthma. Please do not stop taking Prem-SR Tablet 10's without consulting your doctor as it could cause withdrawal symptoms. Avoid consuming alcohol along with Prem-SR Tablet 10's as it could lead to increased drowsiness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies such as killing or harming yourself. Prem-SR Tablet 10's contains Pregabalin, which can decrease sperm count and may affect fertility in men. Do not exceed the prescribed dose or duration of treatment. 

Drug-Drug Interactions: Prem-SR Tablet 10's may interact with oral diabetes medicine (pioglitazone, rosiglitazone), medications used primarily to treat high blood pressure and heart failure (benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril).

Drug-Food Interactions: Avoid alcohol consumption while taking Prem-SR Tablet 10's as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Prem-SR Tablet 10's may have interactions with disease conditions such as severe kidney disease, diabetes, drug or alcohol addiction, heart problems, a mood disorder, depression or suicidal thoughts.

• PIOGLITAZONE
• ROSIGLITAZONE
• BENAZEPRIL
• CAPTOPRIL
• FOSINOPRIL
• LISINOPRIL
• MOEXIPRIL
• PERINDOPRIL
• QUINAPRIL
• RAMIPRIL

• Include food rich in vitamin B and D in your diet.
• Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
• Exercising regularly helps in improving overall health and combating pain.
• Rest well, get plenty of sleep.
• Try taking a warm bath as it can be soothing.
• Avoid smoking and alcohol consumption.
• Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
• Acupuncture can be helpful by stimulating pressure points.
• Using essential oils for massages can help increase circulation.

• Prem-SR Tablet 10's can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position.
• Prem-SR Tablet 10's can cause dry mouth, so in that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).