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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:52 PM IST
Pregout-Pill Tab is used in combination with Misoprostol to induce a medical abortion. It is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help. It contains Mifepristone, which works by blocking the effect of progesterone (female hormone), needed to sustain a pregnancy. In some cases, you may experience side effects such as nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Akumentis Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Pregout-Pill Tab

Pregout-Pill Tab belongs to the class of medication called 'progestin antagonist' used in combination with Misoprostol to induce a medical abortion. Pregout-Pill Tab is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help.

Pregout-Pill Tab contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Pregout-Pill Tab to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete.

Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (which may last up to 30 days), fever, and digestive system discomfort. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised.

Pregout-Pill Tab should be taken in dose and duration as advised by the doctor, preferably with food. It would be best to take it at a fixed time every day. It is a tablet and should be taken orally with a glass of water. In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Pregout-Pill Tab subside with time. But if your vaginal bleeding does not, please visit the doctor immediately, and it requires immediate medical attention.

Pregout-Pill Tab should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting Pregout-Pill Tab if you have or ever had an ectopic pregnancy (when the fetus grows in the fallopian tube), using an intrauterine device, or if you are breastfeeding, any bleeding disorder or heart problem. Do not do strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.

Uses of Pregout-Pill Tab

Treatment of Medical abortion

Medicinal Benefits

Pregout-Pill Tab contains Mifepristone, which is taken in a regimen with Misoprostol to induce medical abortion or terminate a pregnancy before 70 days. It works by blocking the effect of progesterone (female hormone) needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Pregout-Pill Tab to show effect.

Directions for Use

Pregout-Pill Tab should be taken in dose and duration as prescribed by your doctor. Do not chew or crush it; swallow it as a whole.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pregout-Pill Tab

  • Weakness
  • Nausea
  • Uterine cramps
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Infection following abortion
  • Uterine bleeding

Drug Warnings

Women who have an ectopic pregnancy (a pregnancy outside of the uterus, problems with the adrenal glands (the glands near the kidneys), currently taking corticosteroid therapy (medications), have an allergic reaction to mifepristone, misoprostol or similar drugs, have bleeding problems or taking the blood-thinning drug (warfarin, clopidogrel, aspirin, heparin etc.) should not use Pregout-Pill Tab and contact doctor. After using Pregout-Pill Tab if you start feeling sleepy, do not drive or operate heavy machinery. If you use an intrauterine device (IUD), please remove it before taking the Pregout-Pill Tab. Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (herbal supplements to treat mild depression) and grapefruit juice should not be taken when taking Pregout-Pill Tab as it is known to interact. 

Drug Interactions

Drug-Drug Interactions: Pregout-Pill Tab interacts with corticosteroids (dexamethasone), antifungal (ketoconazole, itraconazole), antibiotics (erythromycin, rifampicin),  anti-epileptic (phenytoin, phenobarbital, carbamazepine), immunosuppressants (cyclosporine, tacrolimus, sirolimus), medicines to treat migraine (ergotamine). So, Pregout-Pill Tab should not be taken along with these drugs.

Drug-Food Interactions: Please tell your doctor about all the Vitamins, herbs, and supplements you are taking as the Pregout-Pill Tab may interact with them to produce unpleasant side effects. Also, Pregout-Pill Tab is known to interact with St John’s Wort (a natural remedy used to treat mild depression) and grapefruit juice.

Drug-Disease Interactions: Pregout-Pill Tab should be taken with caution in people with a bleeding problem, confirmed or suspected ectopic pregnancy, heart problem, liver or kidney disease, or vaginal bleeding.

Drug-Drug Interactions Checker List

  • DEXAMETHASONE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • CYCLOSPORINE
  • TACROLIMUS
  • SIROLIMUS
  • ERGOTAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.
  • Avoid chronic stress and physical exercise like running, as it might increase vaginal bleeding.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Get an ultrasound to check if the abortion is done completely to avoid unwanted complications.
  • Try to include heart-healthy omega-3 fatty acid-containing foods or drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Special Advise

  • Pregout-Pill Tab should not be used to end the pregnancy after ten weeks.
  • Contact your doctor immediately if you experience heavy vaginal bleeding after taking this medicine.

Disease/Condition Glossary

Medical abortion: It is a procedure in which medicine is used to end a pregnancy. It is effectively causing abortion if performed in the first 70 days of pregnancy. Vagina bleeding occurs, and if it does not stop, please inform your doctor as it might require medical supervision. Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (which may last up to 30 days), fever, and digestive system discomfort. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised. 

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Alcohol

Unsafe

Alcohol is known to cause excessive drowsiness if taken along with Pregout-Pill Tab and increase uterine bleeding.

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Pregnancy

Unsafe

Pregout-Pill Tab is used for medical abortion. If taken in pregnancy, it can lead to abortion.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before prescribing Pregout-Pill Tab; your doctor will decide whether Pregout-Pill Tab can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Pregout-Pill Tab may reduce alertness or induce sleep and dizziness. If you experience these symptoms, don't drive or operate machinery.

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Liver

Caution

Pregout-Pill Tab to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Pregout-Pill Tab to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Pregout-Pill Tab is not recommended for children below the age of 12. The safety and effectiveness of Pregout-Pill Tab have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Pregout-Pill Tab or not.

Country of origin

India

Manufacturer/Marketer address

204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India
Other Info - PRE0697

FAQs

Pregout-Pill Tab is used in combination with Misoprostol to induce a medical abortion. Pregout-Pill Tab is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help.
No, Pregout-Pill Tab should be taken in the dose and duration as advised by the doctor. Taking it in more than the recommended dose might cause unpleasant side effects like excessive uterine bleeding.
No, the Pregout-Pill Tab is not known to affect any future chances of fertility. Pregout-Pill Tab is used for medical abortion.
If you miss a dose of Pregout-Pill Tab, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
After taking Pregout-Pill Tab, you may or may not experience vaginal bleeding, which does not indicate complete abortion. Your doctor will examine with the performing ultrasonography to confirm if the abortion is complete.
No, the Pregout-Pill Tab does not affect fertility. Use contraception during sexual intercourse as it may lead to unwanted pregnancy if you are not planning it.
Some of the common side effects of Pregout-Pill Tab are nausea, weakness, fever/chills, vomiting, headache, diarrhoea, and dizziness.
Pregout-Pill Tab contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the development of the pregnancy is stopped.
No, taking more than the prescribed dose of Pregout-Pill Tab will not make it more effective and could be dangerous. Please follow the dosage as prescribed by your doctor to avoid potential side effects or complications.
Please inform your doctor if you have a history of liver disease before using Pregout-Pill Tab. The dosage may need to be adjusted by your doctor, as liver impairment can affect how the drug is metabolized.
Swallow Pregout-Pill Tab as a whole with water; do not crush or chew it. The doctor will determine the dose based on your condition.
After taking Pregout-Pill Tab, you may experience cramping or bleeding in the uterus as the medication works to block the hormone progesterone and prepare your body for the next step in the abortion process. Typically, bleeding begins within 24-48 hours after taking Pregout-Pill Tab. It is common to experience other side effects such as nausea, vomiting, diarrhoea, dizziness, or infection following the abortion. Follow-up with your doctor is essential to ensure that the process is complete.

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