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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:51 AM IST

Pregiso 40mg Tablet SR is used to treat and prevent Raynaud's phenomenon, cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), and other conditions involving poor blood flow in the blood vessels (veins and arteries). Besides this, it is also used to relax uterine muscles to prevent premature labour (when the uterus starts contracting for birth earlier than usual). It contains Isoxsuprine, which relaxes and widens the blood vessels (artery/veins) and muscles (like uterine muscle), thereby increasing the blood flow to the muscles and blocking nerves, delaying contraction in premature labour pains, and poor blood flow to organs and other body parts. In some cases, you may experience side effects such as chest pain (angina), irregular heartbeat, nausea, vomiting, and weakness.

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Composition :

ISOXSUPRINE-40MG

Manufacturer/Marketer :

Jabs Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Pregiso 40mg Tablet SR

Pregiso 40mg Tablet SR is used to treat and prevent Raynaud's phenomenon, cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), and other conditions involving poor blood flow in the blood vessels (veins and arteries). Besides this, it is also used to relax uterine muscles to prevent premature labour (when the uterus starts contracting for birth earlier than usual).

Pregiso 40mg Tablet SR contains Isoxsuprine, which relaxes and widens the blood vessels (artery/veins) and muscles (like uterine muscle), thereby increasing the blood flow to the muscles and blocking nerves, delaying contraction in premature labour pains, and poor blood flow to organs and other body parts.

Pregiso 40mg Tablet SR should be taken regularly in dose and duration as advised by the doctor. It would be best to take it at a fixed time every day. Your doctor will advise you on the exact dosage and how often you have to take Pregiso 40mg Tablet SR based on your medical condition. In some cases, you may experience chest pain (angina), irregular heartbeat, nausea, vomiting, and weakness. Most of these side effects of Pregiso 40mg Tablet SR do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Pregiso 40mg Tablet SR should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Also, it is not suitable for some people. Inform your doctor before starting Pregiso 40mg Tablet SR if you have any bleeding disorders or heart problems. Do not do strenuous activities to avoid premature labour. Pregiso 40mg Tablet SR may cause sudden falls in blood pressure, so if you are driving or operating a motor vehicle or doing any hazardous task, avoid it. Do not stand suddenly from a lying position, as you may feel dizzy. Alcohol intake with Pregiso 40mg Tablet SR can also cause dizziness, so one should avoid its intake.

Uses of Pregiso 40mg Tablet SR

Treatment of Blocked blood vessels, Prevention of premature labour.

Medicinal Benefits

Pregiso 40mg Tablet SR contains Isoxsuprine, which is a vasodilator. It relaxes and widens the blood vessels (artery/veins) and muscles (like uterine muscle), thereby relaxing them and increasing blood circulation to these parts. It is recommended to avoid strenuous exercise and work for the best results of Pregiso 40mg Tablet SR. So, it is prescribed for the treatment of cerebrovascular insufficiency (poor blood flow to the brain), peripheral vascular disease (blocked veins of the leg), Buerger's disease (blood clot in arm and legs) and Raynaud's disease (numb and cold sensation due to blocked nerves of hand). It helps in the prevention of preterm labour in pregnant women.

Side Effects of Pregiso 40mg Tablet SR

  • Weakness
  • Dizziness
  • Flushing (feeling of warmth)
  • Upset stomach
  • Vomiting
  • Stomach pain

Directions for Use

Swallow Pregiso 40mg Tablet SR as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Pregiso 40mg Tablet SR should not be given to people allergic to Pregiso 40mg Tablet SR, have low blood pressure (less than 90 mm of Hg), or have a heart or bleeding problem. Tell your doctor you are using the Pregiso 40mg Tablet SR before undergoing dental or other surgery. Your doctor might stop this medicine before the surgery. Pregiso 40mg Tablet SR should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side-effects. Also, lifestyle changes should be continued with Pregiso 40mg Tablet SR for best results and a speedy recovery. Pregiso 40mg Tablet SR may cause dizziness, so if you are sitting, rise slowly to avoid falling and not driving or operating a car. Also, any strenuous exercise or work should be avoided to avoid delivery complications.

Therapeutic Class

BETA- ADRENERGIC BLOCKERS

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

What if I have taken an overdose of Pregiso 40mg Tablet SR

Do not take more than the prescribed dose of Pregiso 40mg Tablet SR as it may cause overdose. The symptoms of overdose include fainting, lightheadedness, weakness, vomiting and nausea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Safe if prescribed

No interaction found; in case of any discomfort, consult your doctor.

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Pregnancy

Safe if prescribed

Pregiso 40mg Tablet SR is a category C pregnancy; studies suggest it is safe and does not harm the baby. Your doctor will still weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Safe if prescribed

Pregiso 40mg Tablet SR is a category C pregnancy; studies suggest it safe and does not pass through the milk. Your doctor will still weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

Drive with caution, Pregiso 40mg Tablet SR may cause blurry vision, and dizziness may occur.

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Liver

Safe if prescribed

There is limited information available on the use of Pregiso 40mg Tablet SR in patients with liver disease. Please consult your doctor for the best advice.

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Kidney

Safe if prescribed

There is limited information available on the use of Pregiso 40mg Tablet SR in patients with kidney disease. Please consult your doctor for the best advice.

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Children

Unsafe

Pregiso 40mg Tablet SR is not recommended for children as the safety and effectiveness of Pregiso 40mg Tablet SR have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Pregiso 40mg Tablet SR or not.

Country of origin

India
Other Info - PR64008

Author Details

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FAQs

Pregiso 40mg Tablet SR is used to treat and prevent Raynaud's phenomenon, cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), and other conditions involving poor blood flow in the blood vessels (veins and arteries). Besides this, it is also used to relax uterine muscles to prevent premature labour (when the uterus starts contracting for birth earlier than usual).
Pregiso 40mg Tablet SR contains Isoxsuprine, which relaxes and widens the blood vessels (artery/veins) and muscles (like uterine muscle), thereby increasing the blood flow to the muscles and blocking nerves, delaying contraction in premature labour pains, and poor blood flow to organs and other body parts.
If you forget to take Pregiso 40mg Tablet SR at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
You should avoid taking Pregiso 40mg Tablet SR if you start feeling dizzy. In this condition, one should avoid driving a motor vehicle, operating heavy machinery and doing hazardous tasks. So, it is better to get up slowly from a lying or resting position.
There are no known reported contraindications to oral use of Pregiso 40mg Tablet SR when administered in recommended doses. Pregiso 40mg Tablet SR should not be given immediately postpartum (childbirth) or in the presence of arterial (blood vessel) bleeding.
If you are taking Pregiso 40mg Tablet SR and undergoing dental surgery, please inform your doctor as Pregiso 40mg Tablet SR might be stopped before the surgery.
No, Pregiso 40mg Tablet SR is in a class of drugs called vasodilators.
You may take Pregiso 40mg Tablet SR with or without food.
It may take several weeks or longer to experience the full effects of this medication. Do not take your medication more frequently than prescribed. It is dependent on individual factors.
The dose is dependent on individual factors. Take Pregiso 40mg Tablet SR exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
To avoid potential interactions and minimise side effects, before using this medication, you should inform your doctor about your medical history, including any ongoing medicines.
In some cases, Pregiso 40mg Tablet SR may cause side effects including weakness, dizziness, flushing (feeling of warmth), upset stomach, vomiting and stomach pain. Most of these side effects of Pregiso 40mg Tablet SR do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

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