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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Nov 23, 2024 | 4:28 PM IST
Pregator Capsule is a combination medicine used to manage neuropathic pain due to damaged nerves. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like dizziness, sleepiness, tiredness, headache, nausea, vomiting, dry mouth, and constipation.
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Manufacturer/Marketer

Micro Labs Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Pregator Capsule

Pregator Capsule is used for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms of neuropathic pain include shooting and burning pain followed by tingling and numbness (loss of sensation). Neuropathic pain can be caused by amputation of limbs, diabetic neuropathy (nerve damage due to excess blood sugar level), excessive alcohol intake (alcoholism) and cancer treatment via chemotherapy.

Pregator Capsule contains Pregabalin (anticonvulsant), Methylcobalamin (vitamin B12), Alpha-lipoic acid (antioxidant), Pyridoxine hydrochloride (vitamin B6), and Folic acid (vitamin B9). Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain and lowering the risk of seizures (fits). Methylcobalamin and Pyridoxine hydrochloride help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and the brain. Folic acid helps in delivering essential nutrients to the nerves. Together, Pregator Capsule provides relief from neuropathic pain.

Use Pregator Capsule as prescribed by your doctor. In some cases, you may experience certain common side effects, such as dizziness, sleepiness, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Pregator Capsule without consulting your doctor, as it could cause withdrawal symptoms. Consult your doctor before starting Pregator Capsule if you are pregnant or breastfeeding. Pregator Capsule may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Pregator Capsule as it could lead to increased dizziness and sleepiness. Pregator Capsule should not be given to children as safety and effectiveness have not been established.

Uses of Pregator Capsule

Treatment of Neuropathic pain

Medicinal Benefits

Pregator Capsule is a combination of five drugs: Pregabalin (anti-convulsant or antiepileptic), methylcobalamin (vitamin B12), alpha-lipoic acid (antioxidant), pyridoxine hydrochloride (vitamin B6), and folic acid (vitamin B9). Pregator Capsule is used to treat neuropathic pain. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain and lowering the risk of seizures. Methylcobalamin and Pyridoxine hydrochloride help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Pregator Capsule helps in providing relief from neuropathic pain.

Directions for Use

Swallow it as a whole with a glass of water; do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pregator Capsule

  • Dizziness
  • Sleepiness
  • Tiredness
  • Nausea
  • Vomiting

Drug Warnings

Do not take Pregator Capsule if you are allergic to any of its contents. Inform your doctor before taking Pregator Capsule if you have/had heart problems or bipolar syndrome. Please do not stop taking Pregator Capsule without consulting your doctor as it could cause withdrawal symptoms. Do not take Pregator Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Pregator Capsule causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Pregator Capsule as it could lead to increased dizziness and sleepiness. Pregator Capsule should not be given to children as safety and effectiveness have not been established. Consult your doctor immediately if you experience suicidal tendencies.

Drug Interactions

Drug-Drug Interaction: Pregator Capsule may have interaction with antidepressants (amitriptyline, duloxetine), pain killers (codeine, morphine, tramadol), anti-convulsant (gabapentin, phenobarbital), anti-anxiety (diazepam), anti-diabetic (metformin), immunosuppressant (methotrexate), anti-rheumatoid (sulfasalazine), antibiotic (chloramphenicol), anti-cancer (altretamine), and anti-Parkinson’s (levodopa).

Drug-Food Interaction: Avoid consumption of alcohol while taking Pregator Capsule as it might cause increased dizziness and sleepiness.

Drug-Disease Interaction:  Pregator Capsule may have interactions with disease conditions, such as suicidal tendencies, angioedema, creatine kinase elevations, peripheral oedema, malabsorption, and anaemia.

Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • CODEINE
  • MORPHINE
  • TRAMADOL
  • GABAPENTIN
  • PHENOBARBITAL
  • DIAZEPAM
  • METFORMIN
  • METHOTREXATE
  • SULFASALAZINE
  • CHLORAMPHENICOL
  • ALTRETAMINE
  • LEVODOPA

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well, and get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

Disease/Condition Glossary

Neuropathic pain: It is a nervous disorder that occurs due to nerve damage caused by chronic progressive nerve disease, limb amputation, diabetes or due to infection or injury. The pain could be intermittent or continuous, and it could feel like a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensation is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain that is not triggered by an injury, the body sends the pain signals unpromptedly. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pregator Capsule as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pregator Capsule ; your doctor will decide whether Pregator Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Pregator Capsule causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Pregator Capsule should not be given to children as the safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - PRE0155

Author Details

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FAQs

Pregator Capsule is used in the treatment of Neuropathic pain.
Pregator Capsule contains Pregabalin, methylcobalamin, alpha-lipoic acid, pyridoxine hydrochloride, and folic acid. It affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Pregator Capsule also helps reduce further nerve damage in neuropathy. It works by improving blood circulation to peripheral body parts and thus relieving pain.
Do not discontinue Pregator Capsule without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Pregator Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregator Capsule ; your doctor will reduce the dose gradually.
People taking Pregator Capsule should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
Pregator Capsule may decrease sperm count and may affect fertility in men. However, it is unclear whether these effects would occur. So it is advisable to ask your doctor about your risk.
No, Pregator Capsule is not a typical painkiller. Pregator Capsule is used to manage neuropathic pain.
To control weight gain associated with Pregator Capsule , you need to make changes in your diet and lifestyle. Avoid high-calorie foods like soft drinks, oily snacks, and sweets. Exercise regularly. Have a balanced diet and avoid alcohol consumption. Consult a doctor if you have any other concerns.
Yes, the use of Pregator Capsule can cause sleepiness or drowsiness. Avoid alcohol intake as it may increase sleepiness. This does not require any medical treatment as this will gradually reduce over time. Please consult the doctor if it persists for longer durations.
Serious side effects of Pregator Capsule are rare which includes allergic reactions, suicidal thoughts, or swelling of limbs. Stop using Pregator Capsule and contact your doctor if you notice any of these signs. Also, watch out for sudden mood changes, thoughts, behaviours, or feelings as these may be signs of suicidal thoughts.
Pregator Capsule may show initial improvement within 2 weeks, but full benefits typically appear after 2-3 months and may take longer for some patients based on their health condition. However, please consult the doctor if you do not notice any improvements.
If you forget to take Pregator Capsule , then take it as soon as you remember and if it is the time for the next dose, skip the missed dose and continue taking a regular dose. Avoid taking the double dose to make up for the forgotten one.
If you accidentally take too much of Pregator Capsule , seek medical attention immediately. Symptoms of Pregator Capsule overdose may include dizziness, drowsiness, confusion, and blurred vision.
No, higher than the recommended dose of Pregator Capsule will not be more effective, instead it can lead to increased side effects. Therefore, do not exceed the recommended dose. If your symptoms worsen, please consult your doctor.
You are recommended to avoid alcohol while taking Pregator Capsule , as it may cause excessive drowsiness or dizziness. Please, consult the doctor if you have any concerns.
If you begin taking Pregator Capsule , regular check-ups with your doctor may be necessary. However, consult your doctor if the prescribed dosage does not improve your symptoms or if you experience any side effects.
Store Pregator Capsule at a temperature below 25°C in a cool and dry place. Protect from light and moisture. Keep it out of reach of children. Pregator Capsule should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
Pregator Capsule contains Methylcobalamin, Pregabalin, Folic acid, Pyridoxine hydrochloride and Alpha Lipoic acid as its active substances.
Take Pregator Capsule as directed by your doctor, with or without food. Swallow it whole with a glass of water. Do not crush, chew, or break it.
While using Pregator Capsule you are recommended to tell your doctor if you are allergic to its active components. Inform your doctor if you have heart issues, bipolar disorder, are pregnant, or breastfeeding. Pregator Capsule is not recommended for children, and alcohol should be avoided. Also inform your doctor, if you have suicidal thoughts or breathing issues, especially if you have COPD, asthma, or related conditions.
Pregator Capsule may interact with amitriptyline (anti-depressants), morphine and oxycodone (pain killer), phenobarbital (anti-consultants), diazepam (anti-anxiety), metformin (anti-diabetic), methotrexate (immunosuppressant), sulfasalazine (anti-rheumatoid), chloramphenicol(antibiotic), levodopa (anti-parkinsons). Therefore, consult your doctor before taking other medicines while on treatment with Pregator Capsule .

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