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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:47 PM IST

Pocaaz-O Oral Suspension is used to prevent and treat fungal infections. It contains posaconazole which works by inhibiting fungal cell growth and causing cell death. In some cases, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, and cough. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Prescription drug

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Composition :

POSACONAZOLE-200MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

About Pocaaz-O Oral Suspension

Pocaaz-O Oral Suspension is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections when other antifungal medicines have not worked, or you have had to stop taking them. It is also indicated for preventing invasive Aspergillus and Candida infections in patients at high risk of developing these infections due to being severely immunocompromised, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

Pocaaz-O Oral Suspension contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Take Pocaaz-O Oral Suspension as prescribed by your doctor. You are advised to take Pocaaz-O Oral Suspension for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood. Most of these side effects of Pocaaz-O Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Pocaaz-O Oral Suspension or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Pocaaz-O Oral Suspension only if the benefits outweigh the risk. Before taking the Pocaaz-O Oral Suspension, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Pocaaz-O Oral Suspension

Pocaaz-O Oral Suspension is used in the treatment of Fungal infections and prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.

Medicinal Benefits

Posaconazole is an antifungal medication present in Pocaaz-O Oral Suspension. It is effective in treating fungal infections in adults. It is also indicated for preventing invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

Side Effects of Pocaaz-O Oral Suspension

  • Diarrhoea
  • Nausea
  • Fever
  • Vomiting
  • Headache
  • Coughing
  • Low potassium levels in the blood

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you are allergic or hypersensitive to any component present in Pocaaz-O Oral Suspension or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Pocaaz-O Oral Suspension only if the benefits outweigh the risk. Before taking the Pocaaz-O Oral Suspension, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions. And also, let your doctor know before prescribing Pocaaz-O Oral Suspension if you have Arrhythmias and QTc Prolongation, liver problems, or low potassium, magnesium, or calcium levels in your blood.

Therapeutic Class

ANTIFUNGALS

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Pocaaz-O Oral Suspension for more than one day.
  • Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Pocaaz-O Oral Suspension.
  • Continue taking your normal regular diet unless your doctor prescribes a specific diet.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, alcohol and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during Pocaaz-O Oral Suspension treatment to enhance a healthy lifestyle practice.

Habit Forming

No

How Pocaaz-O Oral Suspension Works

Pocaaz-O Oral Suspension contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

What if I have taken an overdose of Pocaaz-O Oral Suspension

Take Pocaaz-O Oral Suspension only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Consult your doctor

The interaction of Pocaaz-O Oral Suspension with alcohol is unknown. If you have any concerns regarding this, please discuss with your doctor.

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Pregnancy

Consult your doctor

Pocaaz-O Oral Suspension should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Pocaaz-O Oral Suspension.

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Breast Feeding

Consult your doctor

There is no substantial research yet on using Pocaaz-O Oral Suspension in breastfeeding/nursing mothers. Inform your doctor if you are a nursing mother before taking Pocaaz-O Oral Suspension; your doctor will decide whether Pocaaz-O Oral Suspension can be taken by breastfeeding mothers.

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Driving

Caution

It is unknown whether Pocaaz-O Oral Suspension alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Consult your doctor

Inform your doctor before taking the Pocaaz-O Oral Suspension if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Inform your doctor before taking the Pocaaz-O Oral Suspension if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Consult your doctor

Please consult a doctor before using Pocaaz-O Oral Suspension for children.

Country of origin

India
Other Info - PO45910

Author Details

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FAQs

Pocaaz-O Oral Suspension is used to treat fungal infections and prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.
Pocaaz-O Oral Suspension contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.
Pocaaz-O Oral Suspension is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Pocaaz-O Oral Suspension.
If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.
Like all medicines, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood, although not everybody gets them. Most of these side effects of Pocaaz-O Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Take Pocaaz-O Oral Suspension as prescribed by your doctor. You are advised to take Pocaaz-O Oral Suspension for as long as your doctor has prescribed it for you based on your medical condition.

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