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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Pioz MF G 2 Tablet is used to treat type 2 diabetes. It works by reducing sugar production in the liver, delaying sugar absorption from the intestines, and removing sugar from the blood. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

USV Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Pioz MF G 2 Tablet

Pioz MF G 2 Tablet belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance).

Pioz MF G 2 Tablet is a combination of three antidiabetic drugs, namely: Glimepiride, Metformin, and Pioglitazone. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Pioglitazone works by increasing the sensitivity of liver, muscle, and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, Pioz MF G 2 Tablet helps to control blood sugar levels.

Take Pioz MF G 2 Tablet as prescribed by your doctor. You are advised to take Pioz MF G 2 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. Most of these side effects of Pioz MF G 2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Pioz MF G 2 Tablet or any other medicines, please tell your doctor. Pioz MF G 2 Tablet is not recommended for children. Avoid breastfeeding while taking Pioz MF G 2 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Pioz MF G 2 Tablet as it may harm the unborn baby. Pioz MF G 2 Tablet should be used with caution in elderly patients. Avoid alcohol consumption with Pioz MF G 2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Pioz MF G 2 Tablet .

Uses of Pioz MF G 2 Tablet

Treatment of Type 2 diabetes mellitus

Medicinal Benefits

Pioz MF G 2 Tablet contains three antidiabetic drugs (Glimepiride, Metformin and Voglibose) used in the treatment of type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin reduces the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Pioglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Also, it decreases the amount of glucose produced by the liver and preserves the functioning of beta cells in the pancreas that produces insulin. Thereby, Pioz MF G 2 Tablet helps to control blood sugar levels.

Directions for Use

Take Pioz MF G 2 Tablet with food to avoid stomach upset, or take it as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pioz MF G 2 Tablet

  • Stomach pain
  • Nausea
  • Diarrhoea
  • Vomiting
  • Headache
  • Metallic taste
  • Low blood sugar

Drug Warnings

If you are allergic to Pioz MF G 2 Tablet or any other medicines, please tell your doctor. Pioz MF G 2 Tablet is not recommended for children. Avoid breastfeeding while taking Pioz MF G 2 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Pioz MF G 2 Tablet as it may harm the unborn baby. Pioz MF G 2 Tablet should be used with caution in elderly patients. Avoid alcohol consumption with Pioz MF G 2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Pioz MF G 2 Tablet . Take short, frequent meals and avoid prolonged fasting while taking Pioz MF G 2 Tablet . Beware of symptoms of hypoglycemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug Interactions

Drug-Drug Interaction: Pioz MF G 2 Tablet may have interaction with other antidiabetic drugs (insulin, sitagliptin, empagliflozin), water pill (furosemide), antithyroid drugs (levothyroxine), anticonvulsant (pregabalin).

Drug-Food Interaction: Pioz MF G 2 Tablet may interact with alcohol. Therefore, avoid the consumption of alcohol with Pioz MF G 2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Drug-Disease Interaction: If you have bladder cancer, uncontrolled diabetes, lactic acidosis, diabetic ketoacidosis (accumulation of ketone bodies in the blood), or eye problems caused by diabetes, liver, kidney, or heart problems, inform your doctor before taking Pioz MF G 2 Tablet .

Drug-Drug Interactions Checker List

  • INSULIN
  • SITAGLIPTIN
  • EMPAGLIFLOZIN
  • FUROSEMIDE
  • LEVOTHYROXINE
  • PREGABALIN

Habit Forming

No

Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.

  • Maintain healthy body weight as obesity is also related to the onset of diabetes.

  • Maintain a low fat and a low sugar diet. Replace carbohydrates-containing foods with whole grains, fruits and vegetables as carbohydrates turn to sugars leading to high blood sugar.

  • Avoid consumption of alcohol and quit smoking.

Special Advise

Regular blood tests are recommended while taking Pioz MF G 2 Tablet to monitor blood sugar levels.

Disease/Condition Glossary

Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, damaged retina of eyes or blindness, loss of limbs, sexual dysfunction, and increase chance of heart attack or stroke.

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Pioz MF G 2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Pioz MF G 2 Tablet is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Pioz MF G 2 Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Pioz MF G 2 Tablet if you are breastfeeding.

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Driving

Caution

Pioz MF G 2 Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Pioz MF G 2 Tablet .

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Liver

Caution

Take Pioz MF G 2 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pioz MF G 2 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Pioz MF G 2 Tablet is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.
Other Info - PIO0020

Author Details

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FAQs

Pioz MF G 2 Tablet is used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.
Pioz MF G 2 Tablet contains Glimepiride, Metformin and Pioglitazone. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Pioglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, Pioz MF G 2 Tablet helps to control blood sugar levels.
Pioz MF G 2 Tablet may increase the risk of low blood sugar levels especially with alcohol intake, when you exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
You are not recommended to take Pioz MF G 2 Tablet with pregabalin as it may cause weight gain and fluid retention that could lead to heart failure. However, please consult a doctor before using Pioz MF G 2 Tablet with other medicines.
In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.
You are not recommended to stop taking Pioz MF G 2 Tablet on your own as discontinuing Pioz MF G 2 Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Pioz MF G 2 Tablet , please consult your doctor so that alternative medicine may be prescribed.
Yes, Pioz MF G 2 Tablet may cause stomach upset as a side effect. Drink water/fluids in small, frequent amounts and chew the food properly while eating.
You are recommended to avoid consumption of alcohol with Pioz MF G 2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Inform the doctor if you are taking any other medicines, have any other medical conditions, and if you are pregnant or breastfeeding.
Yes, Pioz MF G 2 Tablet may lead to vitamin B12 deficiency, particularly on long-term use. Consult the doctor if you experience symptoms of vitamin b12 deficiency such as headache, loss of appetite, fatigue, mental impairment, pins and needle sensation, and pale skin.
Store Pioz MF G 2 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Pioz MF G 2 Tablet may cause side effects like stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. If the side effects persist or worsen, please consult your doctor.

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