Pionee TN 400mg/600mg Tablet is an antibiotic medication primarily used to treat diarrhoea, dysentery and stomach infections. Dysentery is an intestinal infection generally lasting for three to seven days, causing severe diarrhoea with blood. Diarrhoea is a condition in which bowel movements are too frequent, leading to loose, watery stools. Acute diarrhoea is a common problem and generally lasts for one or two days, whereas chronic diarrhoea lasts four weeks.

Pionee TN 400mg/600mg Tablet is a combination of two antibiotics, Norfloxacin and Tinidazole, primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin helps by preventing the bacterial cells from dividing and, hence, killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

Pionee TN 400mg/600mg Tablet can be taken with or without food. For best results, take Pionee TN 400mg/600mg Tablet as advised by your doctor. Do not chew, crush, or break it. Like all medicines, Pionee TN 400mg/600mg Tablet may cause side effects, although not everybody gets them. Some side effects of Pionee TN 400mg/600mg Tablet include nausea, dryness of mouth, stomach upset, and headache. Most of these side effects of Pionee TN 400mg/600mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Pionee TN 400mg/600mg Tablet if you are allergic to Pionee TN 400mg/600mg Tablet, tinidazole, norfloxacin, or any of its ingredients, as it can lead to abnormal neurological signs (such as dizziness, vertigo, and difficulty in controlling movements). Norfloxacin present in Pionee TN 400mg/600mg Tablet is known to cause tendon rupture, so be cautious while taking Pionee TN 400mg/600mg Tablet. In patients having myasthenia gravis (muscle weakness), Pionee TN 400mg/600mg Tablet should not be taken as it is known to worsen your condition further. Pionee TN 400mg/600mg Tablet should not be taken if you are pregnant or breastfeeding. Do not start using a new medication without telling your doctor. Diarrhoea can cause dehydration, so please increase the intake of fluids. If you have constipation or have blood in stools, do not take Pionee TN 400mg/600mg Tablet. Consumption of alcohol, along with Pionee TN 400mg/600mg Tablet, can cause stomach irritation and increased drowsiness.

Pionee TN 400mg/600mg Tablet is primarily used to treat dysentery, diarrhoea, and upset stomach. Additionally, when Pionee TN 400mg/600mg Tablet is taken as a course, as directed by a doctor, it helps eradicate and prevent the return of infections caused by microorganisms responsible for digestive tract infections. It is a combination of two antibiotics, norfloxacin, and tinidazole. Pionee TN 400mg/600mg Tablet plays a vital role in treating diarrhoea and dysentery. Norfloxacin helps by preventing the bacterial cells from dividing and, hence, killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

• Nausea
• Dryness of mouth
• Stomach upset
• Nausea
• Headache
• Metallic taste or change in taste
• Loss of appetite, weakness
• Skin rash or itching

Do not take Pionee TN 400mg/600mg Tablet if you are allergic to Pionee TN 400mg/600mg Tablet, tinidazole, norfloxacin, or any of its ingredients. Inform your doctor if you have any kidney or liver problems or any neurologic problems. Norfloxacin present in Pionee TN 400mg/600mg Tablet is known to cause tendon rupture, so be cautious while taking Pionee TN 400mg/600mg Tablet. In patients having myasthenia gravis (muscle weakness), Pionee TN 400mg/600mg Tablet should not be taken as it is known to worsen your condition further. Pionee TN 400mg/600mg Tablet should not be taken if you are pregnant or breastfeeding. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Diarrhoea can cause dehydration, so please increase the intake of fluids. If you have constipation or have blood in stools, do not take Pionee TN 400mg/600mg Tablet. Consumption of alcohol, along with Pionee TN 400mg/600mg Tablet, can cause stomach irritation and increased drowsiness.

Drug-Drug Interaction: Pionee TN 400mg/600mg Tablet may have interaction with pain killers (aspirin, ibuprofen), anti-coagulant/blood thinner (warfarin), anti-gout (probenecid), antibiotics (azithromycin, sulfamethoxazole, ciprofloxacin, trimethoprim, amoxicillin, metronidazole, nitrofurantoin, erythromycin), calcium supplements (calcium/vitamin D), antidiabetics (Glyburide), antiepileptics (Phenobarbital, Phenytoin) and live vaccines (cholera, typhoid).

Drug-Food Interaction: Pionee TN 400mg/600mg Tablet is known to interact with multivitamins, caffeine, dairy products, and multi-minerals.

Drug-Disease Interaction: Pionee TN 400mg/600mg Tablet is known to interact if taken along with colitis (inflammation of the colon), CNS disorders, myasthenia gravis (muscle weakness), kidney or liver problems, peripheral neuropathy (nerve damage of the brain), QT interval prolongation, history of tendon rupture, neurological disorders, blood dyscrasia (abnormal disease of blood).

• ASPIRIN
• IBUPROFEN
• WARFARIN
• PROBENECID
• AZITHROMYCIN
• CIPROFLOXACIN
• TRIMETHOPRIM
• AMOXICILLIN
• METRONIDAZOLE
• NITROFURANTOIN
• ERYTHROMYCIN
• CALCIUM
• CHOLERA VACCINE
• TYPHOID VACCINE
• SULFAMETHOXAZOLE

• Antibiotics can alter the useful bacteria in the stomach, which helps indigestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
• Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
• Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they might hinder antibiotic absorption.
• Avoid consumption of alcohol to treat your condition effectively.
• Avoid the usage of tobacco.
• To cure your condition effectually, complete the full course of Pionee TN 400mg/600mg Tablet even though you find symptomatic relief.

• Diarrhea can cause dehydration, so please increase the intake of fluids.
• Norfloxacin present in Pionee TN 400mg/600mg Tablet is known to cause tendon rupture, so be cautious while taking Pionee TN 400mg/600mg Tablet if you have a tendon rupture history.
• Norfloxacin present in Pionee TN 400mg/600mg Tablet may cause live bacterial vaccines (such as the typhoid vaccine) not to work either. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
• You must avoid being in the sunlight for too long as Pionee TN 400mg/600mg Tablet may make you more sensitive to the sun.

Dysentery: Dysentery is mostly caused by bacterial intestinal infection by the bacteria Shigella, in which there is inflammation in the intestine, particularly the colon. It generally lasts for three to seven days, causing severe diarrhoea with blood.

Diarrhoea: It is a condition in which bowel movements are too frequent, leading to loose, watery stools. Acute diarrhoea is a common problem and generally lasts for one or two days, whereas chronic diarrhoea lasts four weeks.

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms, commonly spherical, rod-shaped, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.