Peptrum 20 Tab belongs to a group of antiulcer medicines called proton pump inhibitors used to treat duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome.

Peptrum 20 Tab contains 'Rabeprazole' that works by blocking the action of the enzyme known as gastric proton pump which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

You are advised to take Peptrum 20 Tab for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as headache, dizziness, diarrhoea, constipation, nausea, vomiting, flatulence (wind), weakness, and runny nose. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have a stomach tumour or liver disease. On long-term treatment, Peptrum 20 Tab may cause low magnesium levels and vitamin B12 levels and increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. Peptrum 20 Tab may cause dizziness and sleepiness, so drive only if you are alert. Peptrum 20 Tab is not recommended for children as safety has not been established. Avoid consuming alcohol along with Peptrum 20 Tab as it could lead to increased drowsiness and can elevate the production of stomach acid.

Peptrum 20 Tab belongs to a group of antiulcer medicines called proton pump inhibitors. Peptrum 20 Tab is used to treat duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome. Peptrum 20 Tab works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps reduce the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers.

• Headache
• Dizziness
• Diarrhoea
• Constipation
• Nausea
• Vomiting
• Flatulence (wind)
• Weakness

Do not take Peptrum 20 Tab if you are allergic to any of its contents. Inform your doctor if you have a stomach tumour or liver disease or if you are due to have a Chromogranin A blood test. On long-term treatment, Peptrum 20 Tab may cause low magnesium levels and vitamin B12 levels and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor before starting Peptrum 20 Tab if you are pregnant or breastfeeding. Peptrum 20 Tab may cause dizziness and sleepiness, so drive only if you are alert. Peptrum 20 Tab is not recommended for children as safety has not been established. Avoid consuming alcohol along with Peptrum 20 Tab as it could lead to increased drowsiness and can elevate the production of stomach acid. Prolonged intake of Peptrum 20 Tab is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions: Peptrum 20 Tab may have interaction with a pain killer (aspirin, naproxen), anti-depressant (duloxetine, amitriptyline), blood thinner (clopidogrel), a drug used to treat hypothyroidism (levothyroxine), anti-HIV (atazanavir), anti-fungal (ketoconazole, itraconazole), anti-cancer (methotrexate), vitamin (cyanocobalamin), and Medicines to help you to sleep or feel more relaxed (such as diazepam or zolpidem).

Drug-Food Interactions: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Drug-Disease Interactions: Inform your doctor if you have Clostridium difficile-associated diarrhoea, liver disease, bone fractures, and hypomagnesemia (low levels of magnesium).

• ASPIRIN
• NAPROXEN
• DULOXETINE
• CLOPIDOGREL
• LEVOTHYROXINE SODIUM
• ATAZANAVIR
• KETOCONAZOLE
• ITRACONAZOLE
• METHOTREXATE
• CYANOCOBALAMIN
• AMITRIPTYLINE
• DIAZEPAM
• ZOLPIDEM

• Eat smaller meals more often.
• Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
• Maintain a healthy weight by regular exercising.
• Avoid lying down after eating to prevent acid reflux.
• Avoid tight-fitting clothes as it might increase the pressure on the abdomen, leading to acid reflux.
• Practise relaxation techniques and avoid stress by doing yoga or meditation.
• Avoid foods such as high-fat, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
• Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by brisk walking or stretching.

• Inform your doctor before taking Peptrum 20 Tab if you are due to have Chromogranin A blood test.
• Peptrum 20 Tab may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking Peptrum 20 Tab .

Acidity: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, peptic ulcer, and Zollinger Ellison syndrome.

Gastroesophageal reflux disease (GERD): It is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.

Duodenal ulcer: It is a painful condition followed by the development of sores or ulcers in the duodenum or stomach lining (first part of the small intestine, i.e., the duodenum).

Zollinger Ellison syndrome: It is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production, leading to peptic ulcers.