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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 22, 2024 | 7:38 PM IST
Pentac-150 Tablet is used to treat indigestion, heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. It is also used to prevent and treat stomach ulcers. It contains Ranitidine, which helps reduce stomach acid. It may cause common side effects like headache, diarrhoea, constipation, and shortness of breath. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

RANITIDINE-150MG

Manufacturer/Marketer

Unipex Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Pentac-150 Tablet

Pentac-150 Tablet is used to treat indigestion, heartburn and acid reflux. Pentac-150 Tablet is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Pentac-150 Tablet is also used to prevent and treat stomach ulcers. Often, Pentac-150 Tablet is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.

Pentac-150 Tablet contains ranitidine, a histamine-2 (H2) receptor blocker that helps reduce stomach acid by blocking the actions of the H2 receptor. The H2 receptor lies in the parietal cells of the stomach wall. It is responsible for the release of gastric acid secretion - extra gastric acid secretion damages the tissues in the food pipe, stomach, and duodenum.

Take this medication exactly as prescribed by your doctor. It would help if you kept taking medicine for as long as your doctor recommends. If you stop early, your symptoms may come back, and your condition may worsen. Pentac-150 Tablet might have common side effects like headache, diarrhoea, constipation, and shortness of breath. These side effects are temporary and may be resolved after some time. However, if these side effects persist, contact your doctor.

It is recommended not to take Pentac-150 Tablet if you are allergic to any components present in Pentac-150 Tablet . If you are pregnant, planning to become pregnant, or are breastfeeding, you should not take this medication unless your doctor says it is necessary. Inform your doctor if you have stomach or intestinal cancer, liver problem, or will have an endoscopy in the future. Also, let your doctor know about your health condition and all the medicines you are taking before taking Pentac-150 Tablet to rule out any side effects.

Uses of Pentac-150 Tablet

Treatment of Gastroesophageal Reflux Disease (GERD), Acid reflux, Heartburn, and Peptic Ulcer.

Medicinal Benefits

Pentac-150 Tablet helps in reducing the excess amount of stomach acid. In turn, it prevents the formation of an ulcer in the stomach (peptic ulcer), gastroesophageal reflux disease (GERD) with or without ulcer, and Zollinger-Ellison Syndrome, in which the stomach makes an exceptionally high amount of acid.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pentac-150 Tablet

  • Headache

  • Constipation

  • Diarrhoea

  • Stomach pain

Drug Warnings

You should avoid taking Pentac-150 Tablet if you are allergic to Pentac-150 Tablet or H2 receptor blockers, have gastric cancer, or have liver disease. If you are a pregnant woman or nursing mother, do not consume Pentac-150 Tablet without first consulting your doctor. Pentac-150 Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), or anti-HIV drug( atazanavir). Let your doctor know if you are taking these medicines. Intake of Pentac-150 Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in stool and mucous), immediately consult the doctor.

Drug Interactions

Drug-Drug Interactions:Pentac-150 Tablet interacts with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir), and antacid (aluminium hydroxide).

Drug-Food Interactions: Drinking alcohol and nicotine (tobacco) with Pentac-150 Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy.

Drug-Disease Interactions: Pentac-150 Tablet interacts with disease conditions, including gastric bleeding, liver/ kidney disease, and low vitamin B12 (anaemia).

Drug-Drug Interactions Checker List

  • WARFARIN
  • KETOCONAZOLE
  • ATAZANAVIR
  • ALUMINUM HYDROXIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.

  • Before going to sleep, raise your bedhead, so your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.

  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid backflow into the food pipe.

  • Include high fibre-containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal.

  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H Pyroli infections.

  • Avoid regular sitting continuously, as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Disease/Condition Glossary

The stomach is usually protected from acid by a mucous layer. In some cases, excess acid production erodes the mucous layer, which leads to complications like acidity. Due to this, acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea and vomiting.

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, the mucous layer gets irritated or eroded due to excess acid production, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterized by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.

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Alcohol

Caution

Drinking alcohol with Pentac-150 Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy. So try to avoid consuming alcohol.

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Pregnancy

Safe if prescribed

Pentac-150 Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

Pentac-150 Tablet should be used in nursing women only if clinically needed, and the benefits outweigh the risks.

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Driving

Caution

Pentac-150 Tablet has no or negligible influence on the ability to drive and use machines. In some cases, Pentac-150 Tablet may cause dizziness and sleep. If you observe these symptoms, do not drive or operate machinery until you feel better.

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Liver

Caution

If you have or had a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Caution

If you have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.

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Children

Safe if prescribed

The dose needs to be adjusted based on your child’s weight.

Country of origin

India

Manufacturer/Marketer address

310, W Mall, Mangalam Palace, Sec-3 Rohini, Delhi-85
Other Info - PEN0283

Author Details

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FAQs

Pentac-150 Tablet is used to treat indigestion, heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Pentac-150 Tablet is also used to prevent and treat stomach ulcers. Often Pentac-150 Tablet is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.
Ranitidine belongs to a class of drugs known as H2 receptor antagonists (gastrointestinal agents). Pentac-150 Tablet works by lessening the quantity of acid produced in your stomach.
You can take Pentac-150 Tablet with or without food. However, if you get symptoms whenever you eat or drink, take your medicine 30 minutes before having a drink, snack, or meal.
Pentac-150 Tablet starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.
Pentac-150 Tablet may have some serious side effects, but these are rare. These side effects may include hives, skin rash, itching, and difficulty in breathing. Inform your doctor in case you notice any of these side effects.
No, Pentac-150 Tablet prevents excess production of stomach acid, causing acid reflux and heartburn. If blood is coming in your stool or mucous, immediately contact the doctor.
The duration of the Pentac-150 Tablet treatment depends on your specific condition and the doctor's recommendation.
Pentac-150 Tablet is a common treatment for gastritis. However, if you have gastritis, it's essential to consult with a healthcare professional before using Pentac-150 Tablet , especially for the long term. They can provide an accurate diagnosis and recommend appropriate alternative therapies.
Pentac-150 Tablet typically starts working within 30 minutes to 1 hour. However, achieving complete symptom relief may take several days of consistent use.
No, the Pentac-150 Tablet is not used for loose motion.
Pentac-150 Tablet typically starts working within 30 minutes. Individual responses may vary from person to person.
Pentac-150 Tablet is a widely used over-the-counter antacid medication and is generally very well tolerated.
Yes, it can be used in children; the dose must be adjusted based on your child's weight. If your child is experiencing heartburn, acid reflux, or other digestive issues, it's important to consult with a paediatrician. They can provide an accurate diagnosis and recommend appropriate alternative treatments that are safe and effective for children.
Yes, Pentac-150 Tablet can cause constipation in some people. While constipation is not a common side effect of Ranitidine, it can occur in some individuals.
Pentac-150 Tablet contains Ranitidine (a histamine-2 (H2) receptor blocker), whereas PAN 40 contains Pantoprazole (proton-pump inhibitors). Both are used to treat heartburn, ulcers, and other gastrointestinal issues. Still, they have different mechanisms of action and are in different drug classes.
Do not take Pentac-150 Tablet for longer than two weeks unless your doctor tells you to. Long-term use of Ranitidine may increase the risk of side effects. If you're taking Ranitidine, discussing this with your doctor and exploring alternative options is essential.
Take Pentac-150 Tablet with or without food as directed by your doctor.
Yes, Ranitidine was once considered an effective medication for treating conditions like heartburn, acid reflux, and ulcers. It works by reducing the amount of acid produced by the stomach.
To ensure safe medication use, always follow your doctor's instructions, read medication labels carefully, take medications at the right time, inform your doctor about allergies or medical conditions, report any side effects, store medications properly, and dispose of them safely. Avoid self-medication, combining medications without consulting your doctor, stopping medications suddenly, sharing medications, and taking expired medications. If you have any questions or concerns, consult with your healthcare provider.
Drinking alcohol with Pentac-150 Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy. So, try to avoid consuming alcohol.
Ranitidine and omeprazole are both used to treat heartburn, ulcers, and other gastrointestinal issues. Still, they have different mechanisms of action and are in different drug classes.

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