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Pemnat 500mg Injection is used to treat Non-small cell lung cancer and malignant pleural mesothelioma. It contains Pemetrexed, which treats cancer by blocking the action of substances that may help the cancer cells multiply. Do not use this medication if you are pregnant or breastfeeding. Women and men should use effective contraception during treatment with Pemnat 500mg Injection and for 6 and 3 months afterwards. It is not recommended for children below 18 years.
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About Pemnat 500mg Injection
Pemnat 500mg Injection belongs to the group of medicines called folate analogue metabolic inhibitors used alone or in combination with other anti-cancer medicines to treat non-small cell lung cancer and malignant pleural mesothelioma (cancer affecting the lining of the lung).
Pemnat 500mg Injection contains Pemetrexed, which works by blocking the action of substances that may help the cancer cells multiply.
In some cases, Pemnat 500mg Injection may cause side effects such as diarrhoea, tiredness, nausea, vomiting, and loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
Do not use Pemnat 500mg Injection if you are pregnant or breastfeeding. Pemnat 500mg Injection is not recommended for children below 18 years. Women and men should use effective contraception during treatment with Pemnat 500mg Injection and for 6 and 3 months afterwards. Inform your doctor about your health condition and medications to rule out any side effects/interactions.
Uses of Pemnat 500mg Injection
Medicinal Benefits
Pemnat 500mg Injection contains Pemetrexed, which belongs to the group of medicines called anti-folate anti-neoplastic agents indicated in the treatment of malignant pleural mesothelioma and non-small cell lung cancer in initial treatment in combination with cisplatin, as maintenance treatment of patients whose disease has not progressed after four cycles of platinum-based first-line chemotherapy and after prior chemotherapy as a single agent. Pemnat 500mg Injection treats cancer by blocking the action of substances that may help the cancer cells multiply.
Side Effects of Pemnat 500mg Injection
Directions for Use
Storage
Drug Warnings
Do not use Pemnat 500mg Injection if you are allergic to any of its components, pregnant or breastfeeding, or if you have taken or plan to receive yellow fever vaccination. Inform the doctor if you have/had heart disease, kidney problems, have had or are going to have radiation therapy, or have accumulation of fluid around the lungs. Seek immediate medical attention if you experience symptoms of fever or infection; pain, sores, redness or swelling in the mouth; chest pain or a fast heartbeat; allergic reaction (skin rash, burning/prickling sensation, or fever); Stevens-Johnson Syndrome or toxic epidermal necrolysis (severe rash, itching, or blistering); low haemoglobin levels (tiredness, feeling faint, paleness, or becoming easily breathless); low platelet count (bleeding from gums/nose/mouth, bleeding that does not stop, unexpected bruising, reddish or pinkish urine); or blood clot in the blood vessels of the lungs (sudden breathlessness, cough with bloody sputum or intense chest pain).
Therapeutic Class
Drug-Drug Interactions
Drug-Food Interactions
Diet & Lifestyle Advise
Habit Forming
How Pemnat 500mg Injection Works
What if I have taken an overdose of Pemnat 500mg Injection
Alcohol
Consult your doctor
It is not known if alcohol affects Pemnat 500mg Injection. Please consult your doctor.
Pregnancy
Unsafe
Pemetrexed belongs to pregnancy category D. The use of Pemnat 500mg Injection should be avoided during pregnancy as it might harm the unborn baby.
Breast Feeding
Unsafe
Breastfeeding must be discontinued during treatment with Pemnat 500mg Injection.
Driving
Caution
Pemnat 500mg Injection may cause tiredness. Caution is advised while driving or operating heavy machinery.
Liver
Consult your doctor
If you have a history of liver disease, inform your doctor before receiving Pemnat 500mg Injection.
Kidney
Caution
Dose adjustment may be needed. If you have a history of kidney disease, inform your doctor before receiving Pemnat 500mg Injection.
Children
Unsafe
Pemnat 500mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established.
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Keep Refrigerated. Do not freeze.
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