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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:46 PM IST
Pegabanyl-M Capsule 10's is used to treat neuropathic pain. It contains Mecobalamin and Pregabalin which work by lowering pain signals to the brain and rejuvenating & protecting the nerves. In some cases, this medicine may cause side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, and dry mouth. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Leeford Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Pegabanyl-M Capsule 10's

Pegabanyl-M Capsule 10's belongs to a group of medications known as 'anticonvulsants' used to manage neuropathic pain due to damaged nerves. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. 

Pegabanyl-M Capsule 10's is a combination of two drugs: Methylcobalamin/Mecobalamin (vitamin B12) and Pregabalin (anti-convulsant). Mecobalamin protects nerve fibres and rejuvenates nerve cells by producing a substance called myelin. Pregabalin works by changing how nerves send messages to the brain. Together, Pegabanyl-M Capsule 10's helps to treat neuropathic pain (pain due to nerve damage). 

Take Pegabanyl-M Capsule 10's as prescribed by your doctor. Depending on your medical condition, you are advised to take Pegabanyl-M Capsule 10's for as long as your doctor has prescribed it for you. In some cases, you may experience common side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, dry mouth, dizziness, sleepiness, and uncoordinated body movements. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Pegabanyl-M Capsule 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Pegabanyl-M Capsule 10's causes drowsiness and dizziness, so drive only if you are alert. Pegabanyl-M Capsule 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Pegabanyl-M Capsule 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Let your doctor know if you have a history of heart disease, severe kidney disease, disorders of the stomach or gut/bowel, and diabetes before using the Pegabanyl-M Capsule 10's. 

Uses of Pegabanyl-M Capsule 10's

Treatment of Neuropathic pain

Medicinal Benefits

Pegabanyl-M Capsule 10's is a combination of two drugs: Mecobalamin and Pregabalin. Mecobalamin is used to restore vitamin B12 in the body to treat damaged nerve conditions due to diabetes or other traumatic situations. It also has a neuroprotective activity that helps the nerve cells to function properly and treat neuropathic pain. On the other side, Pregabalin prevents neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma or epilepsy. Together, Pegabanyl-M Capsule 10's helps to treat neuropathic pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pegabanyl-M Capsule 10's

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Heartburn
  • Dryness in mouth
  • Dizziness
  • Blurred vision

Drug Warnings

Please do not stop taking Pegabanyl-M Capsule 10's without consulting your doctor as it could cause withdrawal symptoms. Women of child-bearing potential should use effective contraception.  Inform your doctor before taking Pegabanyl-M Capsule 10's if you have heart problems, bipolar syndrome, severe liver disease or porphyria, diabetes, and asthma. Please do not stop taking Pegabanyl-M Capsule 10's without consulting your doctor as it could cause withdrawal symptoms. Avoid consuming alcohol along with Pegabanyl-M Capsule 10's as it could lead to increased drowsiness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies such as killing or harming yourself. Pegabanyl-M Capsule 10's contains Pregabalin, which can decrease sperm count and may affect fertility in men. Do not exceed the prescribed dose or duration of treatment. 

Drug Interactions

Drug-Drug Interactions: Pegabanyl-M Capsule 10's may interact with oral diabetes medicine (pioglitazone, rosiglitazone), medications used primarily to treat high blood pressure and heart failure (benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril).

Drug-Food Interactions: Avoid alcohol consumption while taking Pegabanyl-M Capsule 10's as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Pegabanyl-M Capsule 10's may have interactions with disease conditions such as severe kidney disease, diabetes, drug or alcohol addiction, heart problems, a mood disorder, depression or suicidal thoughts.

Drug-Drug Interactions Checker List

  • PIOGLITAZONE
  • ROSIGLITAZONE
  • BENAZEPRIL
  • CAPTOPRIL
  • FOSINOPRIL
  • LISINOPRIL
  • MOEXIPRIL
  • PERINDOPRIL
  • QUINAPRIL
  • RAMIPRIL

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Special Advise

  • Pegabanyl-M Capsule 10's can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position.
  • Pegabanyl-M Capsule 10's can cause dry mouth, so in that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pegabanyl-M Capsule 10's as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pegabanyl-M Capsule 10's; your doctor will decide whether Pegabanyl-M Capsule 10's can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Pegabanyl-M Capsule 10's causes drowsiness, sleepiness, and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Pegabanyl-M Capsule 10's should not be given to children as the safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.
Other Info - PEG0149

FAQs

Pegabanyl-M Capsule 10's is used to treat neuropathic pain.
Pegabanyl-M Capsule 10's is a combination of two drugs: Pregabalin (antiepileptic) and Mecobalamin (vitamin B12). Pregabalin improves nerve signal conduction of damaged nerves. Methylcobalamin is a form of Vitamin B12 that helps in the regeneration of damaged nerves and helps produce the myelin sheath (outer protecting layer of nerves). Thus, Pegabanyl-M Capsule 10's promotes healing of damaged nerve and improves nerve conduction in diabetes or traumatic conditions.
Dry mouth could be a side-effect of Pegabanyl-M Capsule 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Pegabanyl-M Capsule 10's may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.
Do not discontinue Pegabanyl-M Capsule 10's without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Pegabanyl-M Capsule 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pegabanyl-M Capsule 10's; your doctor will reduce the dose gradually.
Pegabanyl-M Capsule 10's is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.
No, Pegabanyl-M Capsule 10's is a specialized painkiller specifically designed to treat neuropathic pain (nerve damage) and support nerve health. Unlike traditional painkillers, it targets nerve signals to reduce pain. It promotes regeneration through the combined effects of Pregabalin and Methylcobalamin.
Do not stop taking Pegabanyl-M Capsule 10's without consulting your doctor, even if you feel better or if it seems ineffective. Sudden discontinuation can lead to withdrawal symptoms. Discuss your concerns with your doctor, who will assess your progress and recommend the best course of action - whether to continue, adjust the dose, or safely discontinue the medication.
Neuropathic pain is caused by nerve damage, leading to feelings like burning, tingling, or shooting pain. It's often chronic and can come from conditions like diabetes or neurological disorders. whereas, muscle pain is from muscle strain or injury and feels more like a dull ache or throb, often from physical activity or overuse.
Pegabanyl-M Capsule 10's combines two drugs: Methylcobalamin (vitamin B12) and Pregabalin (anti-convulsant). Mecobalamin protects nerve fibers and rejuvenates nerve cells by producing a substance called myelin. Pregabalin works by changing how nerves send messages to the brain. Together, Pegabanyl-M Capsule 10's helps to treat neuropathic pain (pain due to nerve damage).
To manage weight gain with Pegabanyl-M Capsule 10's, focus on eating healthy foods such as fruits, vegetables, lean meats, and whole grains. Regular exercise, like walking or swimming, is also important. Be mindful of your portion sizes to avoid overeating, and drink plenty of water daily.
Yes, Pegabanyl-M Capsule 10's may cause sleepiness or drowsiness as a side effect. If you experience this, avoid driving or operating heavy machinery and take some rest. However, this symptom vanishes as your body adjusts to this medication. If these symptoms become more uncomfortable, discuss how to manage them with your doctor.
Pegabanyl-M Capsule 10's may rarely cause serious side effects. These include severe dizziness or fainting, suicidal thoughts and significant mood or behaviour changes. Although these effects are infrequent, seek medical attention immediately if experienced.
Generally, the effects of Pegabanyl-M Capsule 10's may start to be felt within a week of treatment, but it can take up to a few weeks to experience its full benefits. However, its effectiveness depends on your body's response, disease situation, and dose administered.
If you forget a dose of Pegabanyl-M Capsule 10's, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.
A higher dose of Pegabanyl-M Capsule 10's than recommended will not increase its effectiveness. It may lead to negative complications due to overdose, and a higher dose may not be suitable for your health condition. Always consult your doctor, as they will determine the best dose suitable to your specific needs by reducing potential complications. If you have concerns about your dosage, never adjust it without discussing it with your doctor; they will decide the correct dosage for you.
It's best to avoid drinking alcohol while taking Pegabanyl-M Capsule 10's. Alcohol can increase the medication's side effects, like dizziness and sleepiness.
The frequency of doctor visits depends on your specific health condition, treatment plan, and your doctor's recommendation. It's essential to follow up with the visits suggested by your doctor. If you have any concerns regarding side effects, dosage, or effectiveness, don't hesitate to schedule an appointment and consult your doctor immediately.
Store Pegabanyl-M Capsule 10's in a cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine by placing it in a plastic bag and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.
Yes, you can take Pegabanyl-M Capsule 10's along with food. But make sure to take it at the same time each day; this will help you not forget the dose.
Caution is advised if you are pregnant or planning to become pregnant. Consult your doctor before taking Pegabanyl-M Capsule 10's, as they will assess the potential risks and benefits of treatment. Your doctor will help determine whether Pegabanyl-M Capsule 10's is suitable for you during pregnancy, ensuring your and your baby's health and well-being.
Common side effects of Pegabanyl-M Capsule 10's may include nausea, vomiting, stomach pain, diarrhoea, heartburn, dryness in the mouth, dizziness, and blurred vision. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

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