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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Ortoxil 1500 Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of bacteria and thereby helps reduce various bacterial infections like lower respiratory tract infections, urinary tract infections, skin and skin structure infections, septicemia, meningitis, gonorrhoea, and bone and joint infections. It helps by inhibiting the bacterial cell synthesis and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections.
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Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Ortoxil 1500 Injection

Ortoxil 1500 Injection belongs to the class of cephalosporin antibiotics indicated to treat a wide range of bacterial infections including lower respiratory tract infections, urinary tract infections, skin and skin structure infections, septicemia (blood infection), meningitis (infection of brain and spinal cord), gonorrhoea (sexually transmitted infections), bone and joint infections. Ortoxil 1500 Injection is also used to prevent infections during surgery. 

Ortoxil 1500 Injection is a broad-spectrum antibiotic that acts against a wide range of bacteria. It works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.

A healthcare expert will administer Ortoxil 1500 Injection; do not self-administer. In some cases, Ortoxil 1500 Injection may cause side effects such as diarrhoea, nausea, vomiting, pain, and swelling at the site of injection. Most of these side effects do not require medical attention and resolve over time. However, if the side effects persist or worsen, consult your doctor.

Let your doctor know about your medical condition and the medications you are taking to avoid the occurrence of potential interactions. Consult your doctor if you are pregnant, breastfeeding, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of Ortoxil 1500 Injection therapy against the risk to your baby. Ortoxil 1500 Injection may cause dizziness, so drive only if you are alert.

Uses of Ortoxil 1500 Injection

Treatment of Bacterial infections

Medicinal Benefits

Ortoxil 1500 Injection is used to treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, Ortoxil 1500 Injection is also used to prevent infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. Ortoxil 1500 Injection is a broad-spectrum antibiotic that acts against a wide range of bacteria. It works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.

Directions for Use

Ortoxil 1500 Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ortoxil 1500 Injection

  • Pain and swelling at the site of injection
  • Diarrhoea
  • Nausea
  • Vomiting

Drug Warnings

Do not take Ortoxil 1500 Injection if you are allergic to any of the contents. Consult your doctor if you are pregnant or breastfeeding. Inform your doctor if you have kidney or liver problems. Ortoxil 1500 Injection may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience a severe, persistent diarrhoea, or if you find blood or mucus in stools, consult your doctor immediately. Let your doctor know about your medical condition and the medications you are taking to avoid the occurrence of potential interactions.

Drug Interactions

Drug-Drug Interactions: Ortoxil 1500 Injection may interact with aminoglycoside-type antibiotics (gentamicin, neomycin), diuretics (furosemide), gout medications (probenecid), anticoagulants (warfarin), and oral contraceptives or birth control pills (levonorgestrel,   medroxyprogesterone), and certain vaccines (BCG, cholera vaccine live, typhoid vaccine live).

Drug-Food Interactions: Avoid grapefruit juice as it may affect the working of Ortoxil 1500 Injection.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation of the colon), kidney or liver disease.

Drug-Drug Interactions Checker List

  • GENTAMICIN
  • NEOMYCIN
  • FUROSEMIDE
  • PROBENECID
  • WARFARIN
  • LEVONORGESTREL
  • MEDROXYPROGESTERONE
  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE

Habit Forming

No

Diet & Lifestyle Advise

  • After completing the course of Ortoxil 1500 Injection, probiotics should be taken to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. 
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Ortoxil 1500 Injection.
  • Avoid intake of alcoholic beverages with Ortoxil 1500 Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Ortoxil 1500 Injection in fighting off infections.

Special Advise

  • Regular monitoring of blood count, haemoglobin levels, renal and liver function tests are recommended.
  • Ortoxil 1500 Injection might affect lab test results. Inform the person doing the tests that you are taking Ortoxil 1500 Injection.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

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Alcohol

Caution

It is not known if alcohol affects Ortoxil 1500 Injection. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Caution

Please consult the doctor as there are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Ortoxil 1500 Injection.

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Driving

Caution

Ortoxil 1500 Injection may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Limited information is available regarding the use of Ortoxil 1500 Injection in patients suffering from liver impairment. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney problems.

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Children

Safe if prescribed

Ortoxil 1500 Injection can be given safely to children provided a child specialist has prescribed the dose.

Country of origin

India
Other Info - OR63987

Author Details

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FAQs

Ortoxil 1500 Injection belongs to the class of cephalosporin antibiotics indicated to treat a wide range of bacterial infections including lower respiratory tract infections, urinary tract infections, skin and skin structure infections, septicemia (blood infection), meningitis (infection of brain and spinal cord), gonorrhoea (sexually transmitted infections), bone and joint infections. Ortoxil 1500 Injection is also used to prevent infections during surgery.
Ortoxil 1500 Injection works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.
After taking an antibiotic, you may need to wait up to three hours before eating or drinking any dairy products, including milk, butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also affect the working of antibiotics.
Ortoxil 1500 Injection is used to treat bacterial infections and does not treat viral infections such as cough, flu or cold.
Ortoxil 1500 Injection may interact with birth control pills and lower its efficiency. Inform your doctor if you use any birth control pills.
Ortoxil 1500 Injection may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience a severe, persistent diarrhoea, or if you find blood or mucus in stools, consult your doctor immediately. Do not take anti-diarrhoeal medicine on your own.

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