Orthoroze 50mg Capsule belongs to a class of medications called anthraquinones used to treat pain, stiffness, and swelling in joints caused by osteoarthritis. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness.

Orthoroze 50mg Capsule contains Diacerein which works by inhibiting the action of a protein involved in the inflammation and destruction of cartilage. Thereby, it helps to build and repair the cartilage (the soft connective tissue that protects and covers the ends of long bones at the joints) and reduces pain and swelling in the joints.

Take Orthoroze 50mg Capsule as prescribed by your doctor. You are advised to take Orthoroze 50mg Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, flatulence (gas), skin rash, or itching. Most of these side effects of Orthoroze 50mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Orthoroze 50mg Capsule or any other medicines, please tell your doctor. Orthoroze 50mg Capsule is not recommended for children below 15 years of age, and it should be used with caution in elderly patients above 65 years of age. Avoid taking Orthoroze 50mg Capsule if you are pregnant or breastfeeding, and consult a doctor before taking Orthoroze 50mg Capsule. Avoid consumption of alcohol with Orthoroze 50mg Capsule as it may increase the risk of liver damage. You are recommended not to take more than the prescribed dose as it may cause a Orthoroze 50mg Capsule overdose and lead to severe diarrhoea.

Orthoroze 50mg Capsule contains Diacerein, which blocks the action of a protein involved in the inflammation and destruction of cartilage. Thereby, it helps to build and repair the cartilage (the soft connective tissue that protects and covers the ends of long bones at the joints) and reduces pain and swelling in the joints.

• Diarrhoea
• Stomach pain
• Flatulence (gas)
• Skin rash
• Itching

If you are allergic to Orthoroze 50mg Capsule or any other medicines, please tell your doctor. Orthoroze 50mg Capsule is not recommended for children below 15 years of age and it should be used with caution in elderly patients above 65 years of age. Avoid taking Orthoroze 50mg Capsule if you are pregnant or breastfeeding and consult a doctor before taking Orthoroze 50mg Capsule. If you have glucose or galactose malabsorption syndrome, congenital galactosemia, or lactase deficiency, inform your doctor as Orthoroze 50mg Capsule contains lactose. You are recommended to regularly exercise to strengthen muscles and manage weight. Avoid consumption of alcohol with Orthoroze 50mg Capsule as it may increase the risk of liver damage. You are recommended not to take more than the prescribed dose as it may cause a Orthoroze 50mg Capsule overdose and lead to severe diarrhea.

Drug-Drug Interaction: Orthoroze 50mg Capsule may interact with water tablets (furosemide, hydrochlorothiazide) and heart-related medicines (digoxin, digitoxin).

Drug-Food Interaction: Orthoroze 50mg Capsule may interact with alcohol. Therefore, avoid alcohol intake while taking Orthoroze 50mg Capsule as it may increase the risk of liver damage.

Drug-Disease Interaction: If you have intestinal obstruction, Crohn’s disease, ulcerative colitis, liver disease, glucose or galactose malabsorption syndrome, congenital galactosemia or lactase deficiency, inform your doctor before taking Orthoroze 50mg Capsule.

• FUROSEMIDE
• HYDROCHLOROTHIAZIDE
• DIGOXIN
• DIGITOXIN

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

• Performing yoga may also help in improving joint flexibility and pain management.

• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

• Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.

• Acupuncture, massage, and physical therapy may also be helpful.

• Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

• Foods containing flavonoids such as soy, berries, broccoli, grapes, and green tea help in reducing inflammation.

• Avoid smoking and alcohol consumption.

You are recommended to maintain a time gap of a minimum of 2 hours between taking Orthoroze 50mg Capsule and antacids containing calcium, aluminium, or magnesium salts as taking these medicines at the same time may decrease the absorption of Orthoroze 50mg Capsule.

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints, and ligament injuries.