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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:07 PM IST

Origlow-H Cream is used to treat melasma (dark brown patch on skin). It works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Also, it works by acting inside skin cells and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. It increases the renewal of skin cells, which helps in the natural exfoliation of the skin's outer layers. Some people may experience skin pain, acne, redness, irritation, burning, itching, or stinging sensation of the skin. Do not apply on cut, open wound, or burned skin area.

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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Orrin Pharma Llp

Consume Type

TOPICAL

Return Policy

Not Returnable

for this medicine

About Origlow-H Cream

Origlow-H Cream is used to treat melasma (dark brown patch on skin). Melasma, also known as chloasma or mask of pregnancy, is a common skin condition that causes brown patches on the face. It is more common in women than in men. The discoloured (grey-brown) patches occur mostly on the forehead, chin, nose, and cheeks.

Origlow-H Cream contains three medicines, namely: Hydroquinone (skin lightening or bleaching agent), Mometasone (corticosteroid), and Tretinoin (a form of Vitamin A or retinoids). Hydroquinone belongs to the class of skin-lightening agents that work by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Mometasone belongs to the class of corticosteroids that work by acting inside skin cells and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin’s outer layers.

Origlow-H Cream is only for external use. Use Origlow-H Cream as prescribed. Avoid contact of Origlow-H Cream with nose, mouth, eyes, ears, or vagina. Do not apply on a cut, open wound, or burned skin area. In case Origlow-H Cream comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience skin pain, acne, redness, irritation, burning, itching, or stinging sensation of the skin. Most of these side effects of Origlow-H Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Origlow-H Cream or any other medicines, please tell your doctor. If you are pregnant, a nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Origlow-H Cream. Origlow-H Cream is not recommended for children below 12 years of age. Do not apply Origlow-H Cream on ulcerated skin or wounds. Avoid sun exposure while using Origlow-H Cream as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not cover or wrap the treated area with a bandage unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Origlow-H Cream catches fire and burns easily. If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Origlow-H Cream.

Uses of Origlow-H Cream

Treatment of Melasma

Medicinal Benefits

Origlow-H Cream is a combination of three drugs: Hydroquinone, Mometasone, and Tretinoin. Hydroquinone belongs to the class of skin-lightening agents that work by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Mometasone is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin’s outer layers. Also, tretinoin loosens the cells on the skin’s surface and unblocks pores by reducing the production of oil in the skin. Thus, it decreases pimples, whiteheads, and blackheads.

Directions for Use

Origlow-H Cream is only for external use. Wash the face with mild soap and pat the skin dry. Take a small amount of Origlow-H Cream on a fingertip and apply on the clean and dry affected area one time a day at night or as advised by your doctor. Avoid contact of Origlow-H Cream with nose, mouth, eyes, ears or vagina. In case Origlow-H Cream comes in contact with these areas accidentally, rinse with water thoroughly.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Origlow-H Cream

  • Skin pain
  • Acne
  • Redness, irritation, burning, itching, or stinging sensation of the skin

Drug Warnings

If you are allergic to Origlow-H Cream or any other medicines, please tell your doctor. If you are pregnant, a nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Origlow-H Cream. Origlow-H Cream is not recommended for children below 12 years of age. Do not apply Origlow-H Cream on ulcerated skin or wounds. Avoid sun exposure while using Origlow-H Cream as it may make the skin more sensitive to sunlight and cause sunburn. Do not cover or wrap the treated area with a bandage unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Origlow-H Cream catches fire and burns easily. If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Origlow-H Cream.

Drug Interactions

Drug-Drug Interaction: Origlow-H Cream may interact with photosensitizing agents (aminolevulinic acid, porfimer, verteporfin), topical antibiotics (benzoyl peroxide), retinoids (isotretinoin), psoralens (methoxsalen), sensitizer (methyl aminolevulinate), antiseptic (resorcinol), keratolytic agents (salicylic acid, sulfur).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Origlow-H Cream.

Drug-Drug Interactions Checker List

  • AMINOLEVULINIC ACID
  • BENZOYL PEROXIDE
  • ISOTRETINOIN
  • METHOXSALEN
  • SALICYLIC ACID
  • PORFIRMER
  • VERTEPORFIN
  • METHYL AMINOLEVULINATE
  • RESORCINOL
  • SULFUR

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid sun exposure while using Origlow-H Cream as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • Regular exercise can improve your mood and self-esteem, though it doesn’t clear spots. Take a shower immediately after finishing the exercise.
  • Wear a wide-brimmed hat to protect your face from sun exposure.
  • Avoid using skin products that cause irritation, such as skin cleansers or shampoos, harsh soaps, hair removers or waxes, hair colours or permanent chemicals, and skin products with astringents, lime, spices, or alcohol.

Special Advise

  • Avoid using Origlow-H Cream for more than 6-8 weeks without a doctor’s advice. Please consult a dermatologist if the skin condition does not improve after 2-3 months of treatment with Origlow-H Cream.
  • Do not take Origlow-H Cream by mouth. Origlow-H Cream is for use only on the skin (topical use). If Origlow-H Cream gets in your eyes or mouth accidentally, immediately rinse it with cold water.

Disease/Condition Glossary

Melasma: It is also known as chloasma, a common skin condition that causes brown patches on the face. The discoloured (grey-brown) patches occur mostly on the forehead, chin, nose, and cheeks. Melasma may be caused by sun exposure, hormone therapy, pregnancy, birth control pills, thyroid, or even stress. It is more common in women than in men. It may occur in pregnant women, due to hormonal changes during pregnancy and is called a ‘mask of pregnancy and fades away after pregnancy on its own or after stopping the usage of contraceptive pills. It can be treated by using skin-lightening creams, topical steroids, dermabrasion, or chemical peels.

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Alcohol

Caution

The interaction of alcohol with Origlow-H Cream is unknown. Please consult a doctor before consuming alcohol while using Origlow-H Cream.

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Pregnancy

Caution

The safety of Origlow-H Cream in pregnant women is unknown and is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Origlow-H Cream is excreted in human milk. Please consult a doctor before using Origlow-H Cream while breastfeeding.

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Driving

Safe if prescribed

Origlow-H Cream usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Origlow-H Cream in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Origlow-H Cream in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Origlow-H Cream is not recommended for children under 12 years of age, as its safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Jurgyan House, 2-3, Badi Omti, Near Clock Tower, Jabalpur, Madhya Pradesh - 482001,India
Other Info - ORIG768

Author Details

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FAQs

Origlow-H Cream is used to treat melasma (dark brown patch on skin).
Origlow-H Cream contains Hydroquinone, Mometasone and Tretinoin. Hydroquinone is a skin-lightening agent that works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Mometasone is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching and swelling. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin's outer layers.
Yes, Origlow-H Cream may increase the skin sensitivity to sunlight in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.
Yes, Origlow-H Cream may cause skin irritation, burning sensation or itching at the site of application in rare cases. However, if the irritation persists or worsens, stop using Origlow-H Cream and consult a doctor.
You are advised to use moisturizer in the morning every day to restore the fat barrier of the skin that protects the skin from damage. Origlow-H Cream may make the skin more sensitive to extreme weather conditions such as cold and wind. Therefore, wear protective clothing and use moisturizer as required. However, please consult a doctor before using moisturizing lotions or any other products with Origlow-H Cream.
No, Origlow-H Cream is not used to treat diaper rash. Using Origlow-H Cream under the child's nappy enables it to pass through the skin easily and cause adverse effects. However, please consult a doctor before using Origlow-H Cream in children.
It is not recommended to use Origlow-H Cream with benzoyl peroxide, hydrogen peroxide, or any other peroxide products as it may cause skin staining, which can usually be removed with soap and water. However, please consult a doctor before using other medicines with Origlow-H Cream.
Use Origlow-H Cream for as long as your doctor has prescribed it. However, avoid using Origlow-H Cream for more than 6 to 8 weeks without a doctor's advice.
Hormonal contraceptives like oral/vaginal birth control pills, injections, implants, skin patches, and vaginal rings can cause melasma to get worse. So, it is advisable to ask your doctor about using non-hormonal birth control (condom, diaphragm with spermicide) instead.
Use Origlow-H Cream as directed by the physician. Clean and dry the effected area. Apply Origlow-H Cream onto the affected areas of the skin.
Avoid contact of Origlow-H Cream with nose, mouth, eyes, ears or vagina. In case Origlow-H Cream comes in contact with these areas accidentally, rinse with water thoroughly. Do not use it on ulcerated skin or wounds.
Melasma is a skin condition that causes brown patches on the face. The discoloured (grey-brown) patches occur mostly on the forehead, chin, nose, and cheeks.
Melasma may be caused by sun exposure, hormone therapy, pregnancy, birth control pills, thyroid, or even stress.
No, Origlow-H Cream should not be used for acne and pimples as it is used to treat melasma.
Yes, Origlow-H Cream is good for the face to treat melasma.
Store Origlow-H Cream at room temperature, in a dry place. Keep out of sight and reach of children.
No, using more than prescribed dose of Origlow-H Cream will not be more effective. Do not exceed the recommended dose as it does not give quick or better results but increases the risk of side effects.
Yes, Origlow-H Cream can be used during the day or as advised by the physician.
Consult the doctor before using other skincare products along with Origlow-H Cream. Let the doctor know if you are using photosensitizing agents, topical antibiotics, retinoids, vitiligo medicines, antiseptics, or keratolytic agents.
The possible side effects of Origlow-H Cream are acne, redness, irritation, burning, itching, or stinging sensation of the skin. Most of these side effects of Origlow-H Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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