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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:21 PM IST
Oleanz Plus Tablet is used to treat schizophrenia and bipolar disorder (manic depression). It contains Fluoxetine and Olanzapine which work by restoring the balance of certain natural substances in the brain. In some cases, this medicine may cause side effects such as drowsiness, lightheadedness, restlessness, irritability, tremors, dry mouth, constipation, and increased appetite. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Oleanz Plus Tablet

Oleanz Plus Tablet belongs to the class of antipsychotics used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Schizophrenia is characterized by symptoms of hallucinations (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. Oleanz Plus Tablet prevents the occurrence of these symptoms. 

Oleanz Plus Tablet consists of two medicines, namely: Fluoxetine and Olanzapine. Oleanz Plus Tablet works by helping to restore the balance of certain natural substances in the brain. The key action of Oleanz Plus Tablet is to block some of the dopamine receptors in the brain and to correct the overactivity of dopamine. On the other hand, it also affects other brain neurotransmitters, such as serotonin (5-HT), which may lead to its beneficial effects. Altogether Oleanz Plus Tablet may help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life.

You are suggested to take $ame for as long as your doctor has prescribed it. Common side-effects of Oleanz Plus Tablet are drowsiness, lightheadedness, restlessness, irritability, tremor, dry mouth, constipation, increased appetite, extreme fatigue, decreased libido, swelling of the hands or feet, or weight gain. Inform your doctor if any of these side effects persist or worsen.

Do not take Oleanz Plus Tablet if you are allergic (hypersensitive) to any of the ingredients present in this medicine. Inform your doctor if you have a medical history of dementia, glaucoma (increased pressure in the eye), stroke, heart diseases, diabetes, liver or kidney disease, Parkinson’s disease (brain disorder), epilepsy (seizures), prostate problems, a blocked intestine (Paralytic ileus), and blood disorders. Oleanz Plus Tablet may increase blood glucose levels, so inform your doctor immediately if you have symptoms such as increased thirst or urination. It may also cause weight gain and increase fat levels in the body.

Uses of Oleanz Plus Tablet

Treatment of Schizophrenia (mental illness), bipolar disorder (manic depression).

Medicinal Benefits

Oleanz Plus Tablet is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Oleanz Plus Tablet works by helping to restore the balance of certain natural substances in the brain. The key action of Oleanz Plus Tablet is to block some of the dopamine receptors in the brain and to correct the overactivity of dopamine. On the other hand, it also affects other brain neurotransmitters, such as serotonin (5-HT), which may lead to its beneficial effects. Altogether Oleanz Plus Tablet may help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life.

Directions for Use

Swallow the medicines as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oleanz Plus Tablet

  • Drowsiness
  • Dizziness
  • Restlessness
  • Tremor
  • Stomach upset
  • Dry mouth
  • Constipation

Drug Warnings

Do not take Oleanz Plus Tablet if you are allergic (hypersensitive) to any of the ingredients present in this medicine or have a medical history of eye problems such as glaucoma (increased pressure in the eye). Before taking Oleanz Plus Tablet , talk to your doctor if you or your family have a history of blood clots, stroke, or heart diseases and if you are above 65 years and have a history of dementia (memory loss). Oleanz Plus Tablet may cause weight gain and increase blood glucose and cholesterol levels. Inform your doctor if you are previously diagnosed with diabetes, liver or kidney disease, Parkinson’s disease (brain disorder), epilepsy, prostate problems, a blocked intestine (Paralytic ileus) or blood disorders.

Drug Interactions

Drug-Drug Interactions: Oleanz Plus Tablet may interact with other benzodiazepines or anti-anxiety drugs (lorazepam and diazepam) and opioid analgesics (tramadol and codeine).

Drug-Food Interactions: Oleanz Plus Tablet may interact with alcohol, increasing drowsiness.

Drug-Disease Interactions: Oleanz Plus Tablet should be used with caution in patients with dementia, CNS (central nervous system) depression, obesity, eye problems, acute alcohol intoxication (change in mental behaviour after alcohol consumption), brain stroke, heart diseases, hyperlipidemia (lipid alterations), hyperglycemia/diabetes, liver disease, kidney problems, epilepsy, and parkinsonism (brain disorder).

Drug-Drug Interactions Checker List

  • LORAZEPAM
  • TRAMADOL
  • DIAZEPAM
  • CODEINE

Habit Forming

No

Diet & Lifestyle Advise

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine, and activities that can impact your mood. 

  • Exercise daily. Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.

  • You may also practice calming techniques such as meditation and deep breathing exercises.

  • Sleep well. Having enough sleep will help to stabilize your mood.

  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.

  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.

Disease/Condition Glossary

Schizophrenia (psychosis): It is a mental illness in which the processing of brain information is affected. Patients with schizophrenia develop symptoms such as hallucinations (seeing or hearing unreal things), delusions (false beliefs), and become withdrawal from society. They lose the ability to differentiate reality from false beliefs. Patients with bipolar disorders have mood swings ranging from manic episodes of heightened excitement to severe depression. Schizophrenia and bipolar disorder may occur due to genetic factors, alcohol or drug abuse, or mental trauma. Schizophrenia may also occur due to brain injuries or diseases.

Bipolar disorder: It is a mental health condition that affects your moods, which can swing from one extreme to another. It is also known as manic depression.

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Alcohol

Unsafe

Patients taking Oleanz Plus Tablet should avoid taking alcohol as it may increase drowsiness.

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Pregnancy

Caution

Oleanz Plus Tablet should be used in pregnant women only when prescribed by a doctor.

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Breast Feeding

Unsafe

Oleanz Plus Tablet should not be given to breastfeeding mothers.

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Driving

Unsafe

Oleanz Plus Tablet causes drowsiness. So, avoid driving or operating heavy machinery after taking Oleanz Plus Tablet .

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Liver

Caution

Oleanz Plus Tablet should be used with caution in patients with liver diseases.

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Kidney

Caution

Oleanz Plus Tablet should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustments and regular monitoring of electrolytes may be required as it may alter electrolyte levels in the body.

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Children

Unsafe

Oleanz Plus Tablet should not be prescribed in children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - OLE0006

Author Details

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FAQs

Oleanz Plus Tablet is used to treat schizophrenia (mental illness) and bipolar disorder (manic depression). It works by restoring the balance of certain natural substances in the brain.
Oleanz Plus Tablet can decrease anxiety, irritability or agitation. However, you should consult a doctor before using Oleanz Plus Tablet for any condition.
Long-term use of Oleanz Plus Tablet may cause dyskinesia (a movement disorder) in some cases. However, your doctor will prescribe this medication if the benefits outweigh the risks.
Oleanz Plus Tablet can be used to treat mood disorders such as schizophrenia, bipolar disorder, anxiety, and depression. However, you should not take this medication without a doctor’s advice.
Oleanz Plus Tablet may cause decreased libido in men and women. It can cause erectile dysfunction in men as it can alter testosterone levels. Consult a doctor if you experience erectile dysfunction after taking Oleanz Plus Tablet .
Stopping Oleanz Plus Tablet abruptly can cause withdrawal symptoms, and stopping it too early could make your illness come back. Please consult your doctor if you want to stop taking Oleanz Plus Tablet .
Oleanz Plus Tablet may cause severe side effects, such as memory loss and loss of contact with reality. It is important to know that it may raise blood sugar levels in diabetics and in patients who have never had diabetes. It can also induce weight gain and high blood fat levels which are more common in adolescents.
No, Oleanz Plus Tablet is not a sleeping pill. It is an antipsychotic medication used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression).
Oleanz Plus Tablet should be used by pregnant women only when prescribed by a doctor. Please consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy.
Do not discontinue Oleanz Plus Tablet without consulting your doctor as stopping Oleanz Plus Tablet suddenly may cause withdrawal symptoms. To treat your condition effectively, keep taking Oleanz Plus Tablet for the prescribed duration.
Avoid smoking as it might interfere with the working of Oleanz Plus Tablet . Do not consume alcohol while on treatment with Oleanz Plus Tablet as it may cause increased drowsiness.
Common side-effects of Oleanz Plus Tablet are drowsiness, lightheadedness, restlessness, irritability, tremors, dry mouth, constipation, increased appetite, extreme fatigue, decreased libido, swelling of the hands or feet, or weight gain. Inform your doctor if any of these side effects persist or worsen.

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