Olbet-Trio 40mg Tablet belongs to a class of medicines called antihypertensives used to treat hypertension (high blood pressure) and reduce the risk of heart attack or stroke in adults. Hypertension is a condition in which the force of blood against the walls of the artery is very high. It will be an addition to the workload of the heart and arteries.

Olbet-Trio 40mg Tablet is a combination of three drugs, namely: Amlodipine (calcium channel blocker), Chlorthalidone (diuretic), and Olmesartan medoxomil (angiotensin II receptor blocker). Amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. Chlorthalidone belongs to the class of diuretics (water tablets) that works by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Olmesartan medoxomil works by blocking the action of a hormone called angiotensin II in the body that causes the narrowing of blood vessels leading to high blood pressure. Thereby, Olbet-Trio 40mg Tablet widens and relaxes blood vessels. Thus, it lowers high blood pressure.

Take Olbet-Trio 40mg Tablet as prescribed by your doctor. You are advised to take Olbet-Trio 40mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, headache, swelling of ankles, feet, hands, arms, or legs, low or high blood pressure, stomach upset, or tiredness. Most of these side effects of Olbet-Trio 40mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Olbet-Trio 40mg Tablet or any other medicines, please tell your doctor. Olbet-Trio 40mg Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking Olbet-Trio 40mg Tablet and consult a doctor. Drive only if you are alert as Olbet-Trio 40mg Tablet may cause dizziness or drowsiness. You are recommended to avoid alcohol consumption with Olbet-Trio 40mg Tablet as it may increase the risk of low blood pressure.

Olbet-Trio 40mg Tablet contains Amlodipine, Chlorthalidone and Olmesartan medoxomil used to treat high blood pressure. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Amlodipine and Olmesartan medoxomil relax and widens blood vessels. Thus, Olbet-Trio 40mg Tablet lowers high blood pressure and reduces the risk of stroke, heart attack or other heart problems.

• Dizziness
• Headache
• Low or high blood pressure
• Swelling of ankles, feet, hands, arms or legs
• Stomach upset
• Tiredness

If you are allergic to Olbet-Trio 40mg Tablet or any other medicines, please tell your doctor. Olbet-Trio 40mg Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking Olbet-Trio 40mg Tablet and consult a doctor. Avoid taking Olbet-Trio 40mg Tablet if you have low levels of sodium or potassium in blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, severe liver or kidney problems. Drive only if you are alert as Olbet-Trio 40mg Tablet may cause dizziness or drowsiness. You are recommended to avoid alcohol consumption with Olbet-Trio 40mg Tablet as it may increase the risk of low blood pressure.

Drug-Drug Interaction: Olbet-Trio 40mg Tablet may interact with non-steroidal anti-inflammatory drugs (aspirin, indomethacin), antimanic drugs (lithium), blood thinner (heparin), cholesterol-lowering medicine (colesevelam hydrochloride, simvastatin), calcium channel blocker (verapamil, diltiazem), antibiotics (erythromycin, clarithromycin, rifampicin), immunosuppressants (tacrolimus, cyclosporine, everolimus, sirolimus, temsirolimus), water pills (amiloride, spironolactone), heart-related medicines (digoxin).

Drug-Food Interaction: Olbet-Trio 40mg Tablet may interact with St. John’s wort (herbal remedy to treat depression). Also, avoid taking potassium supplements, and salt substitutes containing potassium, or potassium-rich foods such as bananas, sweet potatoes, nuts and noni juice with Olbet-Trio 40mg Tablet as it may result in hyperkalemia (high levels of potassium in the blood) and cause severe adverse effects. Also, Olbet-Trio 40mg Tablet may interact with grapefruit juice and increase the levels of Olbet-Trio 40mg Tablet in blood.

Drug-Disease Interaction: Avoid taking Olbet-Trio 40mg Tablet if you have low levels of sodium or potassium in the blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, severe liver or kidney problems. If you have diabetes, eye pain or decrease in vision, high cholesterol, low blood pressure, heart, liver, or kidney problems, inform your doctor before taking Olbet-Trio 40mg Tablet .

• ASPIRIN
• INDOMETHACIN
• LITHIUM
• HEPARIN
• COLESEVELAM
• SIMVASTATIN
• VERAPAMIL
• DILTIAZEM
• ERYTHROMYCIN
• CLARITHROMYCIN
• RIFAMPICIN
• TACROLIMUS
• CYCLOSPORINE
• EVEROLIMUS
• SIROLIMUS
• TEMSIROLIMUS
• AMILORIDE
• SPIRONOLACTONE
• DIGOXIN

• Minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.

• Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.

• Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, and the way you react in certain situations and do activities that you enjoy by making time for yourself.

• Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.

• Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.

• Quit smoking and avoid the consumption of alcohol.

Monitor your blood pressure regularly and if you notice any fluctuations, please consult a doctor.

Blood pressure is the measurement of the force that the heart uses to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.