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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Ofacin 200mg Tablet is used to treat infections caused by bacteria including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland). It contains Ofloxacin, which works by killing bacteria that cause infections and preventing the further spread of the infection. In some cases, you may experience sleep problems, headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital itching in women, vaginal inflammation (vaginitis) and taste changes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions. Do not take this medicine with dairy products as it may lower its efficacy.
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Prescription drug

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Composition

OFLOXACIN-200MG

Manufacturer/Marketer

Indu Drugs Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Ofacin 200mg Tablet

Ofacin 200mg Tablet is used to treat infections caused by bacteria, including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland). A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. 

Ofacin 200mg Tablet contains antibacterial Ofloxacin, which helps in treating and preventing a wide range of bacterial infections. It is bactericidal and works by killing bacteria that cause infections.  It inhibits the repairing of bacterial cells and kills the bacteria, thereby preventing the further spread of the infection. Ofacin 200mg Tablet is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (which live without oxygen).

Ofacin 200mg Tablet should be taken in the dose and duration as advised by your doctor. It is advised to be taken with food and taken at a fixed time to achieve maximum effect. Do not take Ofacin 200mg Tablet with dairy products as it may lower its efficacy. You may experience sleep problems, headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital itching in women, vaginal inflammation (vaginitis) and taste changes in some cases. Most of these side effects of Ofacin 200mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath, immediately contact the doctor.

Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant, or are breastfeeding. Use of Ofacin 200mg Tablet is associated with an increased risk of tendinitis and tendon (tough tissue that connects muscle to bone) rupture in all ages. People taking Ofacin 200mg Tablet who are over 60 years old are at high risk, especially those who are taking any anti-allergic medicines like corticosteroid drugs. Ofacin 200mg Tablet is contraindicated in people with kidney/heart diseases, and for those who have had lung transplants, its use is not recommended.

Uses of Ofacin 200mg Tablet

Treatment of Bacterial Infections

Medicinal Benefits

Ofacin 200mg Tablet contains the antibiotic Ofloxacin, which helps in treating and preventing a wide range of bacterial infections caused by most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (that live without oxygen). It is bactericidal in nature and works by killing bacteria that cause infections by preventing the formation of the cell wall required for living. It also inhibits the repair of bacterial cells. Altogether it kills the bacteria. Ofacin 200mg Tablet has the advantage of good penetration in most deep tissues and body fluids. Hence, it is also suitable for the treatment of deep tissue and bone bacterial infections.

Directions for Use

Tablet: Take it with or without food (excluding dairy products). Swallow the tablet with a glass of water. Do not break, crush or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ofacin 200mg Tablet

  • Tendon rupture
  • Arthralgia (joint pain)
  • Sleep problems
  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Itching
  • External genital itching in women
  • Vaginal inflammation (vaginitis)
  • Taste changes

Drug Warnings

Do not take Ofacin 200mg Tablet if you are allergic or have had a severe reaction to ofloxacin or any other quinolone or fluoroquinolone antibiotics such as delafloxacin, gemifloxacin, levofloxacin, moxifloxacin, and ciprofloxacin. Taking Ofacin 200mg Tablet may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, a joint or tendon disorder such as rheumatoid arthritis (an autoimmune disorder of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking Ofacin 200mg Tablet may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Dairy products should be avoided along with Ofacin 200mg Tablet. And also, exposure to sunlight should be avoided while taking Ofacin 200mg Tablet as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (QT prolongation) should tell their doctor before taking Ofacin 200mg Tablet.

Drug Interactions

Drug-drug interaction: This medicine may have an interaction with blood thinners (aspirin, warfarin), antidepressants and antipsychotics (clozapine, olanzapine), caffeine-containing medications, insulin, or other anti-diabetic medications (chlorpropamide, glimepiride, glipizide, glyburide, metformin, tolazamide, and tolbutamide), medications for regulating irregular heartbeat (amiodarone, disopyramide, procainamide, quinidine), pain killers (ibuprofen, naproxen). Take Ofacin 200mg Tablet either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminum/iron/zinc, antiulcer agent (sucralfate), or anti-HIV drug (didanosine).

Drug-Food Interaction:  Ofacin 200mg Tablet interacts with dairy products (milk or yogurt) or calcium-fortified juices alone.

Drug-Disease Interaction: Inform your doctor if you have or have ever had tendon rupture, musculoskeletal problem (myopathy, rhabdomyolysis), kidney/heart/lung transplant,  low blood potassium (hypokalemia), kidney disease, rheumatoid arthritis, seizures (fits), epilepsy or any other neurological disorder if you participate in regular physical activity before starting Ofacin 200mg Tablet.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • WARFARIN
  • CLOZAPINE
  • OLANZAPINE
  • CHLORPROPAMIDE
  • GLIMEPIRIDE
  • GLIPIZIDE
  • GLYBURIDE
  • METFORMIN
  • TOLAZAMIDE
  • TOLBUTAMIDE
  • AMIODARONE
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • QUINIDINE
  • IBUPROFEN
  • NAPROXEN
  • SUCRALFATE
  • DIDANOSINE

Habit Forming

No

Diet & Lifestyle Advise

  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Ofacin 200mg Tablet may increase nervousness, sleeplessness, and anxiety caused by caffeine.

  • Probiotics should be taken after taking the full course of Ofacin 200mg Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 

  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Ofacin 200mg Tablet.

  • Avoid alcoholic beverages with Ofacin 200mg Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Ofacin 200mg Tablet in fighting off infections.

Special Advise

Tendon damage (especially to the Achilles tendon) can occur within 48 hours of starting Ofacin 200mg Tablet treatment. The onset of symptoms and signs of the side effects may be delayed several months after stopping treatment. At the first sign of tendinitis (like painful swelling, inflammation), immediately stop taking Ofacin 200mg Tablet. The affected limbs should be appropriately treated (e.g., immobilisation). Corticosteroids medicines (like anti-inflammatory drugs including cortisone, prednisone, prednisolone, methylprednisolone, dexamethasone, betamethasone, hydrocortisone should not be used if signs of tendon rupture occur.

Disease/Condition Glossary

A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our bodies. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. People with weak immune systems or taking immunosuppressive medicine can make them more prone to bacterial infection.

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Alcohol

Unsafe

Alcohol is not known to cause any unpleasant side effects if taken along with Ofacin 200mg Tablet. But intake of alcohol with Ofacin 200mg Tablet may damage your liver. So intake of Ofacin 200mg Tablet should be avoided with Ofacin 200mg Tablet.

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Pregnancy

Unsafe

Ofacin 200mg Tablet is a pregnancy Category C medicine. It is not known whether Ofacin 200mg Tablet will affect pregnant women or fetus or not. Hence, the intake of Ofacin 200mg Tablet should be avoided if you are pregnant or planning to become pregnant as it may harm the baby.

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Breast Feeding

Caution

Ofacin 200mg Tablet is excreted in human milk. But the amount of Ofacin 200mg Tablet absorbed by the nursing infant is unknown. So, it should not be taken while breastfeeding.

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Driving

Caution

Ofacin 200mg Tablet can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

Ofacin 200mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-colored urine, yellowing of or skin/eye.

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Kidney

Caution

Ofacin 200mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Ofacin 200mg Tablet can be given to children but under child specialist medical supervision. Ofacin 200mg Tablet is prescribed to the children to treat complicated urinary tract infections, anthrax infection, or plague infection.

Country of origin

India

Manufacturer/Marketer address

Opp. Naveen Anaj Mandi, Sarverkhera Kashipur, Udham Singh Nagar Uttarakhand
Other Info - OF80946

Author Details

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FAQs

Ofacin 200mg Tablet is used to treat bacterial infections, including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland).
If you miss a dose of Ofacin 200mg Tablet, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
No, Ofacin 200mg Tablet should not be taken along with dairy products as it might affect the absorption and efficacy of Ofacin 200mg Tablet. However, you can take it with a meal that includes these foods or drinks.
Ofacin 200mg Tablet makes your skin sensitive to sunlight known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.
Yes, after taking Ofacin 200mg Tablet, you may have diarrhea. Ofacin 200mg Tablet is an antibiotic that kills or prevents bacterial growth, so in case some good intestinal bacteria which aid in digestion might also get killed. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration).
No, Ofacin 200mg Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor
You are recommended to take Ofacin 200mg Tablet either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc, antiulcer agent (sucralfate) or anti-HIV drug (didanosine).

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