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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:31 PM IST
Ocanash 5 Tablet is used to treat primary biliary cirrhosis (an autoimmune disease caused by damage of bile ducts in the liver). It contains Obeticholic acid, which helps improve liver function by reducing the production and build-up of bile in the liver. It increases the removal of bile from the liver and reduces inflammation.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Ocanash 5 Tablet

Ocanash 5 Tablet is used to treat primary biliary cirrhosis. Primary biliary cholangitis, also known as primary biliary cirrhosis, is an autoimmune disease caused by damage of bile ducts in the liver. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage.  
 
Ocanash 5 Tablet contains ‘Obeticholic acid’, which helps improve liver function by reducing the production and build-up of bile in the liver, increases the removal of bile from the liver, and reduces inflammation, thereby helping treat primary biliary cirrhosis.
 
Take Ocanash 5 Tablet as prescribed. In some cases, you may experience common side effects such as stomach pain, tiredness, dizziness, constipation, and palpitations. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. Ocanash 5 Tablet is not recommended for children and adolescents. Ocanash 5 Tablet may cause dizziness, so drive with caution. It is unknown if alcohol interacts with Ocanash 5 Tablet ; consult your doctor if you have any concerns. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Ocanash 5 Tablet

Treatment of Primary biliary cirrhosis.

Medicinal Benefits

Ocanash 5 Tablet belongs to a group of medicines called farnesoid X-receptor agonists used to treat primary biliary cirrhosis/primary biliary cholangitis. Ocanash 5 Tablet helps improve liver function by reducing the production and build-up of bile in the liver and reduces inflammation, thereby helping treat primary biliary cirrhosis.

Directions for Use

Swallow Ocanash 5 Tablet as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ocanash 5 Tablet

  • Stomach pain
  • Tiredness
  • Dizziness
  • Palpitations (irregular or fast heartbeat)
  • Constipation
  • Thyroid hormone irregularity

Drug Warnings

Do not take Ocanash 5 Tablet if you are allergic to any of its contents; if you have a complete blockage of the biliary tract (liver, bile ducts, and gall bladder). Inform your doctor if you experience itching that is difficult to tolerate. Consult your doctor if you are pregnant or breastfeeding. Ocanash 5 Tablet is not recommended for children or adolescents. Ocanash 5 Tablet may cause dizziness, so drive with caution. Consult a doctor immediately if you experience yellowing of the skin/eyes, black/tarry stools, dark urine, coughing up/vomiting blood, confusion, slurred speech, mood swings, anxiety, swelling in and around the stomach.

Drug Interactions

Drug-Drug Interactions: Ocanash 5 Tablet may interact with xanthines (theophylline), muscle relaxants (tizanidine), blood thinners (warfarin), bile acid sequestrants (cholestyramine, colestipol, colesevelam).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have biliary obstruction, liver impairment, or lipid disorder.

Drug-Drug Interactions Checker List

  • THEOPHYLLINE
  • TIZANIDINE
  • WARFARIN
  • CHOLESTYRAMINE
  • COLESTIPOL
  • COLESEVELAM

Habit Forming

No

Diet & Lifestyle Advise

  • Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu and tempeh.
  • Eat a healthy, well-balanced diet that includes fruits and vegetables.
  • Avoid high-fat, trans-fat, and processed foods.
  • White bread, white pasta and sugars should be avoided.
  • Avoid tobacco and alcohol consumption.

Special Advise

  • Regular blood tests for monitoring liver functioning are advised.

Disease/Condition Glossary

Primary biliary cholangitis: Primary biliary cholangitis, also known as primary biliary cirrhosis, is an autoimmune disease caused by damage to bile ducts in the liver. Bile ducts are the small channels that carry the bile (digestive fluid) from the liver to the small intestine, where it breaks down fats and aids in its absorption. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage. 

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Alcohol

Caution

It is not known if alcohol interacts with Ocanash 5 Tablet . Consult your doctor if you have any concerns.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, as limited information is available regarding the usage of Ocanash 5 Tablet during pregnancy.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Ocanash 5 Tablet can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Ocanash 5 Tablet does not affect your ability to drive. However, you are advised to omit driving if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this. Inform your doctor if you have/had liver cirrhosis.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Ocanash 5 Tablet is not recommended for children or adolescents.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - OCA0035

Author Details

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FAQs

Ocanash 5 Tablet is used to treat primary biliary cirrhosis. Primary biliary cholangitis, also known as primary biliary cirrhosis, is an autoimmune disease caused by damage of bile ducts in the liver. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage.
Ocanash 5 Tablet helps improve liver functioning by reducing the production and build-up of bile in the liver and reduces inflammation.
Do not discontinue Ocanash 5 Tablet without consulting your doctor. To treat your condition effectually, continue taking Ocanash 5 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Ocanash 5 Tablet .
Constipation might be a side-effect of Ocanash 5 Tablet . Drink lots of fluids and eat fibre-rich food if you experience constipation. Talk to your doctor if you have severe constipation.
Consult your doctor before taking Ocanash 5 Tablet along with bile acid-binding resins, as they might lower the effect of Ocanash 5 Tablet . If prescribed, maintain a gap of 4-6hours between Ocanash 5 Tablet and bile acid-binding resins. Bile acid-binding resins are used to lower blood cholesterol levels.
Ocanash 5 Tablet may cause palpitation, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.
Ocanash 5 Tablet is used to treat primary biliary cholangitis (PBC), an autoimmune liver disease. Adults with PBC and individuals who haven't responded to other treatments may need to take OCA, but only if advised by their doctor.
You can use Ocanash 5 Tablet combined with ursodeoxycholic acid to treat primary biliary cholangitis (PBC), but only if your doctor advises.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.
Common side effects of Ocanash 5 Tablet may include stomach pain, tiredness, dizziness, constipation, and palpitations. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.
Please consult your doctor if you are pregnant, as limited information is available regarding the usage of Ocanash 5 Tablet during pregnancy.
Ocanash 5 Tablet is not recommended for children or adolescents.

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