Nuligno Topical Solution belongs to the class of local anaesthetics used to reduce/relieve pain and discomfort associated with skin irritation, burns, scratches, insect bites, skin abrasions, or sunburn. It is also used to treat post-herpetic neuralgia (lasting pain after a shingles infection). Nuligno Topical Solution may also be used to treat premature ejaculation. It is also indicated for the prevention and control of pain in urethritis (inflammation of the urethra). Nuligno Topical Solution may also be used as an adjunct for endotracheal intubation.
 
Nuligno Topical Solution contains 'lidocaine' that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses. Nuligno Topical Solution produces local numbness by blocking the nerve signal in the affected area. Hence, Nuligno Topical Solution produces an anaesthetic effect and helps decrease the sensation of pain. 
 
Use Nuligno Topical Solution as advised by the doctor. In some cases, Nuligno Topical Solution may cause application site reactions such as burning sensation, itching, redness, and irritation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before using Nuligno Topical Solution if you are pregnant or breastfeeding. Nuligno Topical Solution is not recommended for children as safety and effectiveness have not been established. Avoid contact of Nuligno Topical Solution with eyes, nose, or mouth. If contact occurs, rinse with water immediately. Do not apply Nuligno Topical Solution on the swollen skin areas or deep puncture wounds. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Nuligno Topical Solution belongs to the class of local anaesthetics used to reduce/relieve pain and discomfort associated with skin irritation, burns, scratches, insect bites, skin abrasions, or sunburn. It is also used to treat post-herpetic neuralgia (pain due to shingles-a viral infection). Nuligno Topical Solution  is also indicated for the prevention and control of pain in urethritis (inflammation of the urethra). Nuligno Topical Solution may also be used as an adjunct for endotracheal intubation (a medical procedure involving the placement of a tube into the windpipe through the nose or mouth). Nuligno Topical Solution contains 'lidocaine' that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses. Nuligno Topical Solution produces local numbness by blocking the nerve signal in the affected area. Hence, Nuligno Topical Solution produces an anaesthetic effect and helps decrease the sensation of pain. Nuligno Topical Solution may also be used to treat premature ejaculation. It works by reducing the sensitivity of skin tissue and sensation when applied to the penis. Thereby prevents premature ejaculation.

• Burning sensation
• Itching
• Redness
• Irritation

Do not use Nuligno Topical Solution if you are allergic to any of its components. Avoid using Nuligno Topical Solution on larger skin areas or for a prolonged duration. Inform your doctor if you have methemoglobinemia (abnormal methemoglobin in the blood), heart, kidney or liver problems. Consult your doctor before using Nuligno Topical Solution if you are pregnant or breastfeeding. Nuligno Topical Solution is not recommended for children as safety and effectiveness have not been established.

Drug-Drug Interactions: Nuligno Topical Solution may have interaction with other local anaesthetic drugs and anti-arrhythmic drugs (tocainide, mexiletine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have methemoglobinemia (abnormal methemoglobin in the blood) or heart problems such as irregular heartbeat or heart block.

• TOCAINIDE
• MEXILETINE

• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
• Avoid smoking and alcohol consumption.

• Do not apply Nuligno Topical Solution on open wounds, injured skin, or unhealed shingles blisters.

• Wash your hands after use. However, do not wash your hands if you are using Nuligno Topical Solution on your hands.

• If Nuligno Topical Solution comes in contact with eyes, mouth or nose, wash with water immediately. Consult a doctor if irritation persists.

• Do not scratch or rub the skin when it is numb.

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, and cuts.

Local anaesthesia: It causes numbing/loss of sensation to a specific area of the body. It is used to treat pain, or to prevent pain during surgery or medical procedure.

Post-herpetic neuralgia: Post-herpetic neuralgia is a lasting pain in the area of shingles. Shingles is a viral infection that causes painful rashes occurring due to the reactivation of chicken pox virus infection. Symptoms include nerve pain and itchiness.

Premature ejaculation: Premature ejaculation is when a man ejaculates (orgasms) more quickly with less sexual stimulation before the man or his partner would like. This could lead to problems in a sexual relationship. Premature ejaculation is also known as rapid ejaculation, premature climax or early ejaculation. Symptoms include the inability to delay the orgasm or ejaculation for more than a minute after the start of intercourse.