NUCLORYL LIQUID belongs to a class of drugs called 'sedative-hypnotics' primarily used in the short-term treatment of insomnia. Insomnia is a sleep disorder that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) due to various complications like stress, anxiety, and breathing problems.

NUCLORYL LIQUID works by increasing GABA activity, which is a chemical messenger in the brain acting as a natural nerve-calming agent, thereby inducing sleep. Thus, NUCLORYL LIQUID relaxes muscles, reduces anxiety, and helps falls asleep.

Take NUCLORYL LIQUID as prescribed by your doctor. You are suggested to take NUCLORYL LIQUID as long as your doctor has prescribed it after checking your medical condition. Some people may experience dizziness, diarrhea, drowsiness, headache, nausea, vomiting, nose or throat infections, tiredness, stomach pain, double vision, and back pain. Most of these side effects of NUCLORYL LIQUID do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to NUCLORYL LIQUID or any other medicines, please tell your doctor. If you notice that tablets' effect is not as well as at the beginning of the treatment, please consult a doctor as you might have developed tolerance to NUCLORYL LIQUID, and dose adjustment may be required. If you are pregnant or breastfeeding, it is advised to consult a doctor before using NUCLORYL LIQUID. If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a serious condition where breathing stops and repeatedly starts in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking NUCLORYL LIQUID.

NUCLORYL LIQUID is indicated for the treatment of insomnia. This medicine is also used to relieve nervousness before any medical procedure. After taking NUCLORYL LIQUID, it gets converted to 'Trichloroethanol' in the body that works on the brain and relaxes the body to produce good sleep. NUCLORYL LIQUID reduces the time taken to fall asleep and increases the length of deep sleep. This relaxing good night's sleep helps the body strengthen your immune system, restore energy, make new healthy cells, and promote the body's repair.

• Rash
• Vomiting
• Headache
• Dizziness
• Confusion
• Diarrhea
• Constipation
• Flatulence
• Abdominal pain
• Drug Dependence
• Nightmare

 Stop taking NUCLORYL LIQUID and contact your doctor right away if you notice a sudden change in sleep behavior or not being fully awake after waking up or having trouble doing activities you generally do. The effects of NUCLORYL LIQUID may even remain to the next day after you wake up, so it's better to take about 7 to 8 hours of sleep after taking NUCLORYL LIQUID. It would be best to wait for a minimum of 8 hours after taking medicine before you drive or operate machinery. Elderly people are more sensitive to undesirable effects of NUCLORYL LIQUID, especially dizziness or confusion. Don't stop taking NUCLORYL LIQUID without informing your doctor. It may cause withdrawal symptoms like vomiting or nausea.

Drug-Drug Interaction: NUCLORYL LIQUID may have interaction with high blood pressure-lowering medicines (metoprolol), opioid pain killers (hydrocodone, oxycodone, naloxone, tramadol), antidepressants (sertraline, desipramine, fluoxetine, venlafaxine, bupropion, fluvoxamine, escitalopram, amitriptyline, citalopram, duloxetine, mirtazapine), antibiotics (ciprofloxacin, rifampicin), antifungal drugs (ketoconazole), anti-anxiety drugs (alprazolam, clonazepam, lorazepam), antiallergics/antihistamines (diphenhydramine, hydroxyzine), muscle relaxants (cyclobenzaprine), and antiepileptic drugs (gabapentin, pregabalin).

Drug-Food Interaction: NUCLORYL LIQUID may interact with caffeine, St John’s wort (herbal medicine for treating depression) and may reduce the effectiveness of NUCLORYL LIQUID. Also, avoid alcohol intake as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process and reduced physical movements), sleepwalking, or sleep-driving.

Drug-Disease Interaction: Do not take NUCLORYL LIQUID if you have severe liver disease, breathing problems, sleep apnoea (sudden stopping of breathing during sleep), severe muscle weakness, kidney problems, and any history of depression or mental illness.

• DIPHENHYDRAMINE
• AMITRIPTYLINE
• METOPROLOL
• TRAMADOL
• OXYCODONE
• NALOXONE
• SERTRALINE
• FLUOXETINE
• HYDROXYZINE
• ESCITALOPRAM
• CYCLOBENZAPRINE
• ALPRAZOLAM
• GABAPENTIN
• HYDROCODONE
• DULOXETINE
• CLONAZEPAM
• CITALOPRAM
• MIRTAZAPINE
• PREGABALIN
• LORAZEPAM

• Do regular exercise during day time.
• Do not take a nap during day time. Set regular timings to go to bed and wake up.
• Relax at least 1 hour before bedtime by bathing with warm water, listening to music, or reading a book.
• Make the bedroom dark and quiet, and ensure that your pillows and mattresses are comfortable.
• Avoid watching tv, using mobiles or laptops just before bedtime.
• Limit caffeine intake, including tea, coffee, hot chocolate, cola, and energy drinks, as it may reduce the effectiveness of NUCLORYL LIQUID.
• Avoid alcohol consumption as it may increase the risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleepwalking, or sleep-driving.

• You are advised to take NUCLORYL LIQUID on an empty stomach as taking NUCLORYL LIQUID with food may reduce the effect of NUCLORYL LIQUID.
• If you are depressed or have depression in the past, please inform your doctor before taking NUCLORYL LIQUID as it may increase self-harming or suicidal thoughts.
• If you notice any behavioral side effects such as delusions (false belief), nightmares, irritability, restlessness, aggressiveness, or hallucinations (hear, feel or see things that are actually not present), please contact your doctor.

Insomnia: It is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to few weeks and occurs due to stress or life changes. Chronic insomnia may last from more than 3 nights per week to more than 3 months. Insomnia is mostly caused due to depression, stress, anxiety, jet lag, shift work, uncomfortable beds, chronic illness, caffeine, nicotine or alcohol intake, or certain medicines. It may be treated using sleeping pills, behavior therapy, sleep habits changes, and identifying and treating chronic conditions.