NITREST 5MG TABLET belongs to a class of drugs called 'sedative-hypnotics' primarily used in the short-term treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

NITREST 5MG TABLET contains Zolpidem which works by increasing the activity of GABA, which is a chemical messenger in the brain acting as a natural nerve-calming agent, thereby inducing sleep. Thus, NITREST 5MG TABLET relaxes muscles, reduces anxiety, and helps to fall asleep.

Take NITREST 5MG TABLET as prescribed. Your doctor will advise you how often you take NITREST 5MG TABLET based on your medical condition. Some people may experience dizziness, diarrhoea, drowsiness, headache, nausea, vomiting, nose or throat infections, tiredness, stomach pain, double vision, and back pain. Most of these side effects of NITREST 5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to NITREST 5MG TABLET or any other medicines, please tell your doctor. If you notice that the effect of tablets is not as well as at the beginning of the treatment, please consult a doctor as you might have developed tolerance to NITREST 5MG TABLET and dose adjustment may be required. If you are pregnant or breastfeeding, it is advised to consult a doctor before using NITREST 5MG TABLET. If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a serious condition where breathing stops and repeatedly starts in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking NITREST 5MG TABLET.

NITREST 5MG TABLET is a sleeping pill used in the short-term treatment of insomnia (difficulty in falling or staying asleep). NITREST 5MG TABLET increases the activity of GABA (a chemical messenger in brain that acts as natural nerve-calming agent) that is involved in inducing sleep. Thus, NITREST 5MG TABLET relaxes muscles, reduces anxiety and helps to fall asleep. Appropriate life style changes are recommended along with NITREST 5MG TABLET to improve the quality of sleep.

• Dizziness

• Diarrhoea

• Drowsiness

• Headache

• Nausea

• Vomiting

• Nose or throat infections

• Tiredness

• Stomach pain

• Double vision

• Back pain

If you notice that the tablets are not working as well as they did at the beginning of the treatment, please consult a doctor as you might have developed tolerance to NITREST 5MG TABLET and dose adjustment may be required. NITREST 5MG TABLET is a category C pregnancy drug and is not recommended for use during pregnancy as it may cause adverse effects on the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using NITREST 5MG TABLET. If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking NITREST 5MG TABLET. Maintain a time gap of a minimum of 8 hours between taking NITREST 5MG TABLET and driving to reduce the risk of increased adverse effects.

Drug-Drug Interaction: NITREST 5MG TABLET may have interaction with high blood pressure-lowering medicines (metoprolol), opioid pain killers (hydrocodone, oxycodone, naloxone, tramadol), antidepressants (sertraline, desipramine, fluoxetine, venlafaxine, bupropion, fluvoxamine, escitalopram, amitriptyline, citalopram, duloxetine, mirtazapine), antibiotics (ciprofloxacin, rifampicin), antifungal drugs (ketoconazole), anti-anxiety drugs (alprazolam, clonazepam, lorazepam), antiallergics/antihistamines (diphenhydramine, hydroxyzine), muscle relaxants (cyclobenzaprine), and antiepileptic drugs (gabapentin, pregabalin).

Drug-Food Interaction: NITREST 5MG TABLET may interact with caffeine, St John’s wort (herbal medicine for treating depression), and may reduce the effectiveness of NITREST 5MG TABLET. Also, avoid alcohol intake as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process and reduced physical movements), sleepwalking, or sleep-driving.

Drug-Disease Interaction: Do not take NITREST 5MG TABLET if you have severe liver disease, breathing problems, sleep apnoea (sudden stopping of breathing during sleep), severe muscle weakness, kidney problems, and any history of depression or mental illness.

• METOPROLOL
• OXYCODONE
• NALOXONE
• TRAMADOL
• SERTRALINE
• AMITRIPTYLINE
• DIPHENHYDRAMINE
• CITALOPRAM
• CLONAZEPAM
• DULOXETINE
• FLUOXETINE
• GABAPENTIN
• HYDROXYZINE
• ESCITALOPRAM
• LORAZEPAM
• PREGABALIN
• MIRTAZAPINE
• ALPRAZOLAM
• CYCLOBENZAPRINE
• HYDROCODONE

• Do regular exercise during day time.

• Do not take nap during day time. Set regular timings to go to bed and wake up.

• Relax yourself at least 1 hour before bedtime by taking a bath with warm water, listening to music or reading a book.

• Make the bedroom dark and quiet and ensure that your pillows and mattresses are comfortable.

• Avoid watching tv, using mobiles or laptops just before bedtime.

• Limit caffeine intake including tea, coffee, hot chocolate, cola and energy drinks as it may reduce the effectiveness of NITREST 5MG TABLET.

• Avoid consumption of alcohol as it may increase risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleep walking or sleep driving.

• You are advised to take NITREST 5MG TABLET on empty stomach as taking NITREST 5MG TABLET with food may reduce the effect of NITREST 5MG TABLET.

• If you are depressed or have had depression in the past, please inform your doctor before taking NITREST 5MG TABLET as it may increase self-harming or suicidal thoughts.

• If you notice any behavioral side effects such as delusions (false belief), nightmares, irritability, restlessness, aggressiveness, or hallucinations (hear, feel or see things that are actually not present), please contact your doctor.

• If you are allergic to any sugars, inform your doctor as NITREST 5MG TABLET contains lactose.

Insomnia: It is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to few weeks and occurs due to stress or changes in life. Chronic insomnia may last from more than 3 nights per week to more than 3 months. Insomnia is mostly caused due to depression, stress, anxiety, jet lag, shift work, uncomfortable beds, chronic illness, caffeine, nicotine or alcohol intake or due to certain medicines. It may be treated using sleeping pills, behaviour therapy, changes in sleep habits, identifying and treating chronic conditions.