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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Dec 7, 2024 | 2:26 PM IST
Nippo SP 100mg/500mg/10mg Tablet is used to treat mild to moderate pain. It can relieve pain, swelling, and inflammation associated with various chronic (long-term) conditions, such as rheumatoid arthritis (joint pain, especially in the hands and feet) and osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back). It can also relieve acute (short-term) pain such as toothache, ear pain, throat pain, muscle ache, and backache. It may cause side effects such as nausea, vomiting, indigestion, stomach pain, headache, heartburn, and diarrhoea.
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Nippo SP 100mg/500mg/10mg Tablet

Nippo SP 100mg/500mg/10mg Tablet belongs to the class of medications called ‘analgesics’ used to treat mild to moderate pain. It can relieve pain, swelling, and inflammation associated with various chronic (long-term) conditions, such as rheumatoid arthritis (joint pain, especially in the hands and feet) and osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back). It can also relieve acute (short-term) pain such as toothache, ear pain, throat pain, muscle ache, and backache.

Nippo SP 100mg/500mg/10mg Tablet is a combination medicine that contains Nimesulide, Paracetamol, and Serratiopeptidase. Nimesulide and Paracetamol are pain killers. They can also reduce fever and inflammation. They act by blocking the action of chemical messengers responsible for pain, fever, and inflammation. On the other hand, Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation and promotes healing.

Nippo SP 100mg/500mg/10mg Tablet is available in the form of a tablet. It would be best if you took this Nippo SP 100mg/500mg/10mg Tablet precisely as prescribed by your doctor. Nippo SP 100mg/500mg/10mg Tablet may cause side effects such as nausea, vomiting, indigestion, stomach pain, headache, heartburn, and diarrhoea. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult a doctor immediately.

Do not take Nippo SP 100mg/500mg/10mg Tablet if you are allergic to any of its contents. Nippo SP 100mg/500mg/10mg Tablet should not be used in patients with liver failure, severe kidney failure, heart failure, gastric ulcers, bleeding disorders, and alcohol or drug abuse. Before taking Nippo SP 100mg/500mg/10mg Tablet, inform your doctor if you are pregnant or breastfeeding. Nippo SP 100mg/500mg/10mg Tablet should not be given to children below 12 years of age. In elderly people, Nippo SP 100mg/500mg/10mg Tablet may be given with caution. Alcohol should not be taken while using Nippo SP 100mg/500mg/10mg Tablet as it further increases the risk of liver damage. Nippo SP 100mg/500mg/10mg Tablet may not affect your ability to drive. However, do not drive or operate heavy machinery if you feel dizzy.

Uses of Nippo SP 100mg/500mg/10mg Tablet

Treatment of Mild to moderate pain.

Medicinal Benefits

Nippo SP 100mg/500mg/10mg Tablet is a combination medicine that contains Nimesulide, Paracetamol, and Serratiopeptidase. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID). Paracetamol is an analgesic and antipyretic. Both medicines can reduce pain and fever. They act by blocking the action of chemical messengers responsible for pain, fever, and inflammation. Serratiopeptidase is an enzyme. It causes thinning of the fluids around the damaged tissue, thereby making fluid drainage easier in the swollen tissue. This effect reduces swelling and promotes faster healing. Together, Nippo SP 100mg/500mg/10mg Tablet can effectively reduce pain, swelling, and inflammation.

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not crush, chew, or break the tablet. You can take Nippo SP 100mg/500mg/10mg Tablet with food to avoid stomach upset. The dose and duration will be decided by your doctor based on your health condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nippo SP 100mg/500mg/10mg Tablet

  • Nausea
  • Vomiting
  • Indigestion
  • Stomach pain
  • Headache
  • Heartburn
  • Diarrhoea

Drug Warnings

Nippo SP 100mg/500mg/10mg Tablet may cause liver damage on higher doses or when used for prolonged periods. So, if you notice signs of liver damage such as loss of appetite, nausea, vomiting, unexplained weight loss, dark urine, and fatigue, or if you have abnormal liver function tests, discontinue the treatment immediately and consult your doctor. Do not use other analgesics while using Nippo SP 100mg/500mg/10mg Tablet. Nippo SP 100mg/500mg/10mg Tablet may have affected fertility, so it is not recommended for women trying to conceive. Nippo SP 100mg/500mg/10mg Tablet may interfere with blood clotting, so it is recommended to stop using this medicine at least 2 weeks before surgery.

Drug Interactions

Drug-Drug Interactions: Nippo SP 100mg/500mg/10mg Tablet may interact with other nonsteroidal anti-inflammatory drugs or pain killers (ibuprofen, diclofenac, and naproxen, etc.), blood thinners (warfarin and clopidogrel), medicines used to treat nausea and vomiting (metoclopramide and domperidone), an antidepressant (lithium), water pills, anticancer drug (methotrexate), and a medication used to suppress the immune system (cyclosporine), and medicine used to lower cholesterol levels (cholestyramine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Nippo SP 100mg/500mg/10mg Tablet should not be used in patients with liver failure, severe kidney failure, heart failure, gastric ulcers, bleeding disorders, and alcohol or drug abuse.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • DICLOFENAC
  • NAPROXEN
  • WARFARIN
  • CLOPIDOGREL
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • LITHIUM
  • METHOTREXATE
  • CYCLOSPORINE
  • CHOLESTYRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.

  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In the chronic conditions of arthritis or joint pain, fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids with a minimum level of chemicals called cytokines, which ramp up inflammation.

  • Your sitting posture is important, especially when have pain and inflammation condition. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. It can be temporary (acute) or lifelong (chronic). Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. At the same time, chronic pain lasts lifelong and can occur due to severe inflammation or tissue damage, such as in cases of osteoarthritis and rheumatoid arthritis. Extreme tissue pain and inflammation caused due to sprains, strains, trauma, or post-surgery may require a prolonged amount of time to heal.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.

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Alcohol

Caution

Consumption of alcohol may increase the risk of liver damage and serious side effects.

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Pregnancy

Unsafe

Nippo SP 100mg/500mg/10mg Tablet is not recommended for use in pregnancy. Please consult your doctor if you are pregnant before taking this medicine.

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Breast Feeding

Unsafe

Nippo SP 100mg/500mg/10mg Tablet should not be used in breastfeeding mothers as it may pass into breastmilk and cause unwanted effects to the nursing baby. However, if prescribed, the doctor may advise you to stop breastfeeding.

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Driving

Safe if prescribed

Nippo SP 100mg/500mg/10mg Tablet may not affect your ability to drive. However, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Unsafe

Nippo SP 100mg/500mg/10mg Tablet should not be used if you have severe liver disease, as this medicine may worsen your condition.

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Kidney

Caution

Nippo SP 100mg/500mg/10mg Tablet should be used with caution if you have kidney problems. your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Nippo SP 100mg/500mg/10mg Tablet is not recommended for use in children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

SCF 223, 1st & 2nd Floor, Motor Market, Manimajra Chandigarh - 160101 , India
Other Info - NI85620

FAQs

Nippo SP 100mg/500mg/10mg Tablet is used to treat mild to moderate pain. It can relieve pain, swelling, and inflammation associated with various chronic (long-term) conditions, such as rheumatoid arthritis (joint pain, especially in the hands and feet) and osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back). It can also relieve acute (short-term) pain such as toothache, ear pain, throat pain, muscle ache, and backache.
Nippo SP 100mg/500mg/10mg Tablet contains Nimesulide, Paracetamol, and Serratiopeptidase. Nimesulide and Paracetamol are painkillers and can also reduce fever and inflammation. They act by blocking the action of chemical messengers responsible for pain, fever, and inflammation. Serratiopeptidase is an enzyme that can reduce swelling and promote the healing of damaged tissue. Together, Nippo SP 100mg/500mg/10mg Tablet can effectively treat pain, swelling, and inflammation associated with various conditions.
Nippo SP 100mg/500mg/10mg Tablet contains Nimesulide and Paracetamol, which may cause liver damage when used in higher doses or longer durations. So, take this medicine for a dose and duration as intended by your doctor. Also, avoid alcohol intake while using this medicine, as alcohol may increase the risk of liver damage.
In general, Nippo SP 100mg/500mg/10mg Tablet is given for short-term pain relief. So, you can stop taking this medicine if your pain subsides. However, it is advised to consult your doctor before stopping this medication.
Nippo SP 100mg/500mg/10mg Tablet may cause side effects such as nausea, vomiting, indigestion, stomach pain, headache, heartburn, and diarrhoea. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult a doctor immediately.
You can use other painkillers if prescribed by your doctor. However, ensure other painkillers don't contain nimesulide, paracetamol, and serratiopeptidase to avoid an overdose.
Do not exceed the recommended dose or duration of Nippo SP 100mg/500mg/10mg Tablet, as this can lead to serious side effects such as liver damage or stomach problems. Taking more than the prescribed dose or using it for a prolonged period can be harmful. If you experience unexplained weight loss, dark urine, or fatigue, which may be signs of liver damage, seek medical attention immediately. Additionally, if your pain persists or is severe, do not adjust the dose on your own. Always consult your doctor first for proper guidance and care.
Nippo SP 100mg/500mg/10mg Tablet should be stored in a cool and dry place, away from direct sunlight. Keep it out of reach of children.

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