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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:45 PM IST
Nicostariv 2mg Injection prevents or treats angina pectoris (heart-related chest pain). It contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels, relaxes these muscle cells, and widens blood vessels. Thus, it reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, it helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.
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Prescription drug

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Composition :

NICORANDIL-2MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Nicostariv 2mg Injection

Nicostariv 2mg Injection belongs to a class of medication called 'vasodilators' used to prevent or treat angina pectoris (heart-related chest pain) in adults who cannot take beta-blockers (blood pressure-lowering pills). Angina pectoris is a kind of chest pain due to decreased blood flow to the heart. It is a symptom of coronary artery disease.

Nicostariv 2mg Injection contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels. Thereby, Nicostariv 2mg Injection reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicostariv 2mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

Nicostariv 2mg Injection will be administered by a healthcare professional; do not self-administer. Some people may experience headache, nausea, vomiting, dizziness, weakness or flushing (reddening of the skin). Most of these side effects of Nicostariv 2mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Nicorandil or any other medicines, inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Nicostariv 2mg Injection. Drive only if you are alert as Nicostariv 2mg Injection may cause dizziness or weakness. Avoid alcohol consumption with Nicostariv 2mg Injection as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Nicostariv 2mg Injection as it may affect blood pressure.

Uses of Nicostariv 2mg Injection

Treatment of Angina pectoris (heart-related chest pain)

Medicinal Benefits

Nicostariv 2mg Injection contains Nicorandil, a potassium-channel activator used to prevent or treat angina pectoris (chest pain). Nicostariv 2mg Injection works by opening potassium channels present on the muscle cells within the blood vessels' walls and relaxing these muscle cells and widening blood vessels. Thereby, Nicostariv 2mg Injection reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicostariv 2mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart. Nicostariv 2mg Injection is given to adults who cannot tolerate other heart medicines such as calcium antagonists or beta-blockers. 

Side Effects of Nicostariv 2mg Injection

  • Headache
  • Nausea
  • Vomiting
  • Dizziness
  • Weakness
  • Flushing (reddening of the skin)

Directions for Use

Nicostariv 2mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Nicorandil or any other medicines, please tell your doctor. Avoid taking Nicostariv 2mg Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems. If you are pregnant or breastfeeding, please consult a doctor. Nicostariv 2mg Injection is not recommended for children as safety and effectiveness were not established. Drive only if you are alert as Nicostariv 2mg Injection may cause dizziness or weakness. Avoid alcohol consumption with Nicostariv 2mg Injection as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Nicostariv 2mg Injection as it may affect blood pressure. If you notice in blood in stools while taking Nicostariv 2mg Injection, inform your doctor immediately as it may be due to ulcers in the stomach, intestines or back passage. 

Therapeutic Class

VASODILATORS

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low-salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

How Nicostariv 2mg Injection Works

Nicostariv 2mg Injection contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels. Thereby, Nicostariv 2mg Injection reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicostariv 2mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

What if I have taken an overdose of Nicostariv 2mg Injection

As Nicostariv 2mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Nicostariv 2mg Injection as it may cause severely low blood pressure.

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Pregnancy

Consult your doctor

There is limited information on the use of Nicostariv 2mg Injection in pregnant women. Usually, it is not recommended for pregnant women. Therefore, if you are pregnant or planning pregnancy, please inform your doctor.

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Breast Feeding

Consult your doctor

There is limited information on the use of Nicostariv 2mg Injection in breastfeeding mothers. Therefore, please inform your doctor if you are a breastfeeding mother.

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Driving

Caution

Nicostariv 2mg Injection may cause dizziness or weakness in some people. Therefore, avoid driving if you feel dizzy or weak after taking Nicostariv 2mg Injection.

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Liver

Caution

Take Nicostariv 2mg Injection with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Nicostariv 2mg Injection with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Consult your doctor

Nicostariv 2mg Injection is not recommended for children as safety and effectiveness were not established. However, please consult a doctor if you have any concerns regarding this.

Country of origin

India
Other Info - NI97952

Author Details

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FAQs

Nicostariv 2mg Injection is used to treat Angina pectoris (heart-related chest pain).
Nicostariv 2mg Injection contains Nicorandil which works by relaxing and widening blood vessels. Thereby, Nicostariv 2mg Injection reduces the workload of the heart by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicostariv 2mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.
Nicostariv 2mg Injection may cause headache as a common side effect, especially in the first few days of treatment. However, if the condition persists or worsens, please consult a doctor so that the dose may be reduced initially.
Nicostariv 2mg Injection is not recommended for patients with severe hypotension (low blood pressure) as it may increase the risk of worsening the condition. Therefore, inform your doctor if you have low blood pressure before taking Nicostariv 2mg Injection.
You are not recommended to take aspirin (pain reliever) with Nicostariv 2mg Injection as co-administration of these two medicines may increase the risk of ulcers or other adverse effects. However, please consult a doctor before taking other medicines with Nicostariv 2mg Injection.
You are recommended to avoid taking Nicostariv 2mg Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems such as left ventricular failure with low filling pressure, cardiac decompensation or cardiogenic shock.
You are not recommended to take more than the prescribed dose of Nicostariv 2mg Injection as it may cause Nicostariv 2mg Injection overdose resulting in symptoms such as weakness, dizziness (signs of low blood pressure), and fast or irregular heartbeat. However, if you experience any of these symptoms while taking Nicostariv 2mg Injection, please consult a doctor immediately.

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